1/0/0/0 METABOLISM 1/1/0/0 amino-acid metabolism 1/1/1/0 amino-acid biosynthesis 1/1/10/0 amino-acid degradation (catabolism) 1/1/4/0 regulation of amino-acid metabolism 1/1/7/0 amino-acid transport 1/1/99/0 other amino-acid metabolism activities 1/2/0/0 nitrogen and sulphur metabolism 1/2/1/0 nitrogen and sulphur utilization 1/2/4/0 regulation of nitrogen and sulphur utilization 1/2/7/0 nitrogen and sulphur transport 1/20/0/0 secondary metabolism 1/20/17/0 biosynthesis of secondary products derived from primary amino acids 1/20/17/3 biosynthesis of amines 1/3/0/0 nucleotide metabolism 1/3/1/0 purine-ribonucleotide metabolism 1/3/10/0 metabolism of cyclic and unusual nucleotides 1/3/13/0 regulation of nucleotide metabolism 1/3/16/0 polynucleotide degradation 1/3/19/0 nucleotide transport 1/3/4/0 pyrimidine-ribonucleotide metabolism 1/3/7/0 deoxyribonucleotide metabolism 1/3/99/0 other nucleotide-metabolism activities 1/4/0/0 phosphate metabolism 1/4/1/0 phosphate utilization 1/4/4/0 regulation of phosphate utilization 1/4/7/0 phosphate transport 1/4/99/0 other phosphate metabolism activities 1/5/0/0 C-compound and carbohydrate metabolism 1/5/1/0 C-compound and carbohydrate utilization 1/5/4/0 regulation of C-compound and carbohydrate utilization 1/5/7/0 C-compound, carbohydrate transport 1/5/99/0 other carbohydrate metabolism activities 1/6/0/0 lipid, fatty-acid and isoprenoid metabolism 1/6/1/0 lipid, fatty-acid and isoprenoid biosynthesis 1/6/10/0 regulation of lipid, fatty-acid and isoprenoid biosynthesis 1/6/13/0 lipid and fatty-acid transport 1/6/16/0 lipid and fatty-acid binding 1/6/4/0 breakdown of lipids, fatty acids and isoprenoids 1/6/7/0 lipid, fatty-acid and isoprenoid utilization 1/6/99/0 other lipid, fatty-acid and isoprenoid metabolism activities 1/7/0/0 metabolism of vitamins, cofactors, and prosthetic groups 1/7/1/0 biosynthesis of vitamins, cofactors, and prosthetic groups 1/7/10/0 transport of vitamins, cofactors, and prosthetic groups 1/7/4/0 utilization of vitamins, cofactors, and prosthetic groups 1/7/7/0 regulation of vitamins, cofactors, and prosthetic groups 1/7/99/0 other vitamin, cofactor, and prosthetic group activities 10/0/0/0 CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION 10/1/0/0 intracellular communication 10/1/1/0 unspecified signal transduction 10/1/1/3 second messenger formation 10/1/1/99 other unspecified signal transduction activities 10/1/10/0 osmosensing 10/1/10/11 key kinases 10/1/10/13 key phosphatases 10/1/10/1 receptor proteins 10/1/10/5 mediator proteins 10/1/10/99 other osmosensing activities 10/1/15/0 nutritional response pathway 10/1/15/11 key kinases 10/1/15/13 key phosphatases 10/1/15/1 receptor proteins 10/1/15/3 second messenger formation 10/1/15/7 G-proteins 10/1/15/99 other nutritional-response activities 10/1/15/9 regulation of G-protein activity 10/1/20/0 pheromone response generation 10/1/20/11 key kinases 10/1/20/13 key phosphatases 10/1/20/1 receptor proteins 10/1/20/7 G-proteins 10/1/20/99 other pheromone response activities 10/1/20/9 regulation of G-protein activity 10/1/5/0 morphogenesis 10/1/5/11 key kinases 10/1/5/7 G-proteins 10/1/5/99 other morphogenetic activities 10/1/5/9 regulation of G-protein activity 10/1/99/0 other signal-transduction activities 11/0/0/0 CELL RESCUE, DEFENSE, CELL DEATH AND AGEING 11/1/0/0 stress response 11/10/0/0 cell death 11/11/0/0 ageing 11/13/0/0 degradation of exogenous polynucleotides 11/4/0/0 DNA repair (direct repair, base excision repair and nucleotide excision repair) 11/7/0/0 detoxificaton 11/7/1/0 detoxification involving cytochrome P450 11/99/0/0 other cell rescue activities 13/0/0/0 IONIC HOMEOSTASIS 13/1/0/0 homeostasis of metal ions 13/4/0/0 homeostasis of other ions 2/0/0/0 ENERGY 2/1/0/0 glycolysis and gluconeogenesis 2/10/0/0 tricarboxylic-acid pathway 2/13/0/0 respiration 2/16/0/0 fermentation 2/19/0/0 metabolism of energy reserves (glycogen, trehalose) 2/22/0/0 glyoxylate cycle 2/25/0/0 oxidation of fatty acids 2/7/0/0 pentose-phosphate pathway 2/99/0/0 other energy generation activities 3/0/0/0 CELL GROWTH, CELL DIVISION AND DNA SYNTHESIS 3/1/0/0 cell growth 3/10/0/0 sporulation and germination 3/13/0/0 meiosis 3/16/0/0 DNA synthesis and replication 3/19/0/0 recombination and DNA repair 3/22/0/0 cell cycle control and mitosis 3/22/1/0 cell cycle check point proteins 3/25/0/0 cytokinesis 3/4/0/0 budding, cell polarity and filament formation 3/7/0/0 pheromone response, mating-type determination, sex-specific proteins 3/99/0/0 other cell growth, cell division and DNA synthesis activities 30/0/0/0 CELLULAR ORGANIZATION (proteins are localized to the corresponding organelle) 30/1/0/0 organization of cell wall 30/10/0/0 nuclear organization 30/13/0/0 organization of chromosome structure 30/16/0/0 mitochondrial organization 30/19/0/0 peroxisomal organization 30/2/0/0 organization of plasma membrane 30/22/0/0 endosomal organization 30/25/0/0 vacuolar and lysosomal organization 30/3/0/0 organization of cytoplasm 30/4/0/0 organization of cytoskeleton 30/5/0/0 organization of centrosome 30/7/0/0 organization of endoplasmatic reticulum 30/8/0/0 organization of Golgi 30/9/0/0 organization of intracellular transport vesicles 30/90/0/0 extracellular/secretion proteins 30/99/0/0 other cellular organization 4/0/0/0 TRANSCRIPTION 4/1/0/0 rRNA transcription 4/1/1/0 rRNA synthesis 4/1/4/0 rRNA processing 4/1/99/0 other rRNA-transcription activities 4/3/0/0 tRNA transcription 4/3/1/0 tRNA synthesis 4/3/3/0 tRNA processing 4/3/6/0 tRNA modification 4/3/99/0 other tRNA-transcription activities 4/5/0/0 mRNA transcrition 4/5/1/0 mRNA synthesis 4/5/1/1 general transcription activities 4/5/1/4 transcriptional control 4/5/1/7 chromatin modification 4/5/3/0 mRNA processing (splicing) 4/5/5/0 mRNA processing (5'-, 3'-end processing, mRNA degradation) 4/5/99/0 other mRNA-transcription activities 4/7/0/0 RNA transport 4/99/0/0 other transcription activities 5/0/0/0 PROTEIN SYNTHESIS 5/1/0/0 ribosomal proteins 5/10/0/0 tRNA-synthetases 5/4/0/0 translation (initiation, elongation and termination) 5/7/0/0 translational control 5/99/0/0 other protein-synthesis activities 6/0/0/0 PROTEIN DESTINATION 6/1/0/0 protein folding and stabilization 6/10/0/0 assembly of protein complexes 6/13/0/0 proteolysis 6/13/1/0 cytoplasmic degradation 6/13/4/0 lysosomal and vacuolar degradation 6/13/7/0 other proteolytic degradation 6/4/0/0 protein targeting, sorting and translocation 6/7/0/0 protein modification (glycolsylation, acylation, myristylation, palmitylation, farnesylation and processing) 6/99/0/0 other protein-destination activities 7/0/0/0 TRANSPORT FACILITATION 7/1/0/0 ion channels 7/10/0/0 amino-acid transporters 7/13/0/0 lipid transporters 7/16/0/0 purine and pyrimidine transporters 7/19/0/0 allantoin and allantoate transporters 7/22/0/0 transport ATPases 7/25/0/0 ABC transporters 7/28/0/0 drug transporters 7/4/0/0 ion transporters 7/4/1/0 metal ion transporters (Cu, Fe, etc.) 7/4/4/0 other cation transporters (Na ,K ,Ca ,NH4 ,etc.) 7/4/7/0 anion transporters (Cl, SO4, PO4, etc.) 7/7/0/0 sugar and carbohydrate transporters 7/99/0/0 other transport facilitators 8/0/0/0 INTRACELLULAR TRANSPORT 8/1/0/0 nuclear transport 8/10/0/0 peroxisomal transport 8/13/0/0 vacuolar transport 8/16/0/0 extracellular transport (secretion) 8/19/0/0 cellular import 8/22/0/0 cytoskeleton-dependenttransport 8/4/0/0 mitochondrial transport 8/7/0/0 vesicular transport (Golgi network, etc.) 8/99/0/0 other intracellular-transport activities 9/0/0/0 CELLULAR BIOGENESIS (proteins are not localized to the corresponding organelle) 9/1/0/0 biogenesis of cell wall (cell envelope) 9/10/0/0 nuclear biogenesis 9/13/0/0 biogenesis of chromosome structure 9/16/0/0 mitochondrial biogenesis 9/19/0/0 peroxisomal biogenesis 9/2/0/0 biogenesis of plasma membrane 9/22/0/0 endosomal biogenesis 9/25/0/0 vacuolar and lysosomal biogenesis 9/4/0/0 biogenesis of cytoskeleton 9/7/0/0 biogenesis of endoplasmatic reticulum 9/8/0/0 biogenesis of Golgi 9/9/0/0 biogenesis of intracellular transport vesicles 9/99/0/0 other cellular biogenesis activities 90/0/0/0 RETROTRANSPOSONS AND PLASMID PROTEINS 98/0/0/0 CLASSIFICATION NOT YET CLEAR-CUT 99/0/0/0 UNCLASSIFIED PROTEINS