Dr Chris Creevey
Dr Creevey completed a double honours degree in Computer Science and Biology in 1997 and a research masters in Ecology in 1999. In 2002 he received his PhD from the National University of Ireland for his work in the area of phylogenetics and comparative microbial genomics. Following this he worked as a postdoctoral researcher for the McInerney Lab in NUI Maynooth developing methods of resconstructing phylogenetic supertrees and detecting horizontal gene transfer (HGT) in genomic data. In 2005 he took up a postdoctoral position in the Euorpean Molecular Biology Laboratory (EMBL) in Heidelberg, Germany where the focus of his research involved the reconstruction of the tree of life, and the use of metagenomic and expressed sequence tag (EST) data for the phylogenetic analysis of unculturable organisms or for those we have no genomic information. In 2009 Dr. Creevey was awarded a Science Foundation Ireland Stokes Lecturership, at Teagasc, (The Irish agriculture and food development authority) in Ireland where his group worked on identifying the genomic factors influencing phenotypic changes in organisms from Bacteria to Eukaryotes, and the development of novel approaches to investigating metagenomic data from rumen microbial communities. He started his current position in IBERs in 2013.
- BRM5820 - Animal Breeding and Genetics
- BR14310 - Evolution and the Diversity of Life
- BR23820 - Tropical Zoology Field Course
Dr. Creevey is currently the Theme Director of Research for Animal and Aquatic Sciences in IBERS. He is also part of the Herbivore Gut Ecosystems group where he lab specialises in using computational approaches to understanding the ecology and evolution of microbial ecosystemsMy research interests include:
- Developing novel computational approaches to understanding the complex interaction of the host-associated microbiomes.
- Understanding the effect of host-associated microbial community structure on the efficiency and health of the host
- Metagenomic and metatranscriptomic analysis of microbial communities.
- Application of graph (phylogenetic and network) techniques to metagenomic and metatranscriptomic samples.
- Analysis of whole genomes of microbial organisms.
- Development of novel approaches for phylogenomic and evolutionary analyses.
For more information see the Creevey lab website.
The rumen microbiome: an underexplored resource for novel antimicrobial discovery. npj Biofilms and Microbiomes 3 (1) 33 10.1038/s41522-017-0042-12017.
Changes in the total fecal bacterial population in individual horses maintained on a restricted diet over 6 weeks. Frontiers in Microbiology 1502 10.3389/fmicb.2017.015022017.
Transcriptomics of liver and muscle in Holstein cows genetically divergent for fertility highlight differences in nutrient partitioning and inflammation processes. BMC Genomics 17 603 10.1186/s12864-016-2938-1 Cadair2016.
An ultra-high density genetic linkage map of perennial ryegrass (Lolium perenne) using genotyping by sequencing (GBS) based on a reference shotgun genome assembly. Annals of Botany 118 (1) pp. 71-87. 10.1093/aob/mcw081 Cadair2016.
De novo Genome Sequencing and Gene Prediction in Lolium perenne, Perennial Ryegrass. In (eds) Breeding in a World of Scarcity: Proceedings of the 2015 Meeting of the Section “Forage Crops and Amenity Grasses” of Eucarpia. Springer Nature pp. 127-131. 10.1007/978-3-319-28932-8_19 Cadair2016.
Interaction of preimplantation factor with the bovine global endometrial transcriptome. British Society of Animal Science Annual conference. Cadair2016.
Horizontal gene flow from Eubacteria to Archaebacteria and what it means for our understanding of Eukaryogenesis. Philosophical Transactions of the Royal Society B: Biological Sciences 370 (1678) 20140337 10.1098/rstb.2014.0337 Cadair2015.
Differential gene expression in the endometrium reveals cytoskeletal and immunological genes in lactating dairy cows genetically divergent for fertility traits. Reproduction, Fertility and Development 29 (2) pp. 274-282. 10.1071/RD15128 Cadair2015.
Whole genome association study identifies regions of the bovine genome and biological pathways involved in carcass trait performance in Holstein-Friesian cattle. BMC Genomics 15 (1) 837 10.1186/1471-2164-15-837 Cadair2014.
Assessment of methods for amino acid matrix selection and their use on empirical data shows that ad hoc assumptions for choice of matrix are not justified. BMC Evolutionary Biology 6 29 10.1186/1471-2148-6-292006.
Genome phylogenies indicate a meaningful alpha-proteobacterial phylogeny and support a grouping of the mitochondria with the Rickettsiales. Molecular Biology and Evolution 23 (1) pp. 74-85. 10.1093/molbev/msj009 Cadair2006.
The Opisthokonta and the Ecdysozoa may not be clades: stronger support for the grouping of plant and animal than for animal and fungi and stronger support for the Coelomata than Ecdysozoa. Molecular Biology and Evolution 22 (5) pp. 1175-1184. 10.1093/molbev/msi102 Cadair2005.
Fatty acid biosynthesis in Mycobacterium tuberculosis: lateral gene transfer, adaptive evolution, and gene duplication. Proceedings of the National Academy of Sciences of the United States of America 100 (18) pp. 10320-10325. 10.1073/pnas.1737230100 Cadair2003.