Dr Dylan Wyn Phillips

PhD

Dr Dylan Wyn Phillips

Lecturer

Contact Details

Teaching

Research

I completed my PhD at Aberystwyth and have since continued my research which focuses on understanding and manipulating the meiotic DNA repair pathways in a range of key crop species. These complex repair pathways are responsible for generating the genetically diverse populations that plant breeders select their elite lines from. The aim of the research is to enhance the transferred important traits from diverse germplasm into commercial varieties. Genome editing technology has already had a dramatic effect on how research is performed and will undoubtedly revolutionise the way plant breeding is performed. I am involved in the development and implementation of the CRISPR-Cas9 technology in IBERS, and have a keen interest in improving current plant transformation methods.

Publications

Colas, I, Macaulay, M, Higgins, JD, Phillips, D, Barakate, A, Posch, M, Armstrong, SJ, Franklin, FCH, Waugh, R & Ramsay, L 2016, 'A spontaneous mutation in MutL-Homolog 3 (HvMLH3) affects synapsis and crossover resolution in the barley desynaptic mutant des10' New Phytologist, vol 212, no. 3, pp. 693-707. DOI: 10.1111/nph.14061
Phillips, D, Jenkins, G, Macaulay, M, Nibau, C, Wnetrzak, J, Fallding, DS, Colas, I, Oakey, H, Waugh, R & Ramsay, L 2015, 'The effect of temperature on the male and female recombination landscape of barley' New Phytologist, vol 208, no. 2, pp. 421-429. DOI: 10.1111/nph.13548
Martin, AC, Shaw, P, Phillips, D, Reader, S & Moore, G 2014, 'Licensing MLH1 sites for crossover during meiosis' Nature Communications, vol 5, 4580 . DOI: 10.1038/ncomms5580
Zheng, T, Nibau, C, Phillips, DW, Jenkins, G, Armstrong, SJ & Doonan, JH 2014, 'CDKG1 protein kinase is essential for synapsis and male meiosis at high ambient temperature in Arabidopsis thaliana' Proceedings of the National Academy of Sciences of the United States of America, vol 111, no. 6, pp. 2182-2187. DOI: 10.1073/pnas.1318460111
Phillips, DW, Wnetrzak, J, Nibau, CS, Barakate, A, Ramsay, L, Wright, F, Higgins, JD, Perry, RM & Jenkins, G 2013, 'Quantitative high resolution mapping of HvMLH3 foci in barley pachytene nuclei reveals a strong distal bias and weak interference' Journal of Experimental Botany, vol 64, no. 8, pp. 2139-2154. DOI: 10.1093/jxb/ert079
Phillips, DW, Nibau, CS, Wnetrzak, J & Jenkins, G 2012, 'High Resolution Analysis of Meiotic Chromosome Structure and Behaviour in Barley (Hordeum vulgare L.)' PLoS One, vol 7, no. 6. DOI: 10.1371/journal.pone.0039539
Phillips, D, Nibau, C, Wnetrzak, J, Ramsay, L & Jenkins, G 2011, 'Assaying pairing and recombination in barley (Hordeum vulgare)' Paper presented at 3rd British Meiosis Meeting, Sheffield, United Kingdom of Great Britain and Northern Ireland, 2011, .
Wnetrzak, J, Phillips, D, Nibau, C, Fallding, D, Jones, N & Jenkins, G 2010, 'Manipulation of meiotic recombination in barley (Hordeum vulgare)' PlantMicro-Wales Meeting, Aberystwyth, United Kingdom of Great Britain and Northern Ireland, 2010 - 2010, .
Phillips, D, Nibau, C, Ramsey, L, Waugh, R & Jenkins, G 2010, 'Development of a molecular cytogenetic recombination assay for barley' Cytogenetic and Genome Research, vol 129, no. 1-3, pp. 154-161. DOI: 10.1159/000314335
Halpin, C, Barakate, A, Waugh, R, Ramsay, L, Jenkins, G, Phillips, D, Armstrong, S, Higgins, J & Franklin, C 2009, 'Manipulating meiosis: Crossovers from Arabidopsis to crops' International Conference on Arabidopsis Research, Edinburgh, United Kingdom of Great Britain and Northern Ireland, 2009, .
Phillips, D, Nibau, C, Fallding, D, Timofejeva, L, Jones, N & Jenkins, G 2009, 'Assaying recombination in barley (Hordeum vulgare)' Monogram Meeting, Bristol, United Kingdom of Great Britain and Northern Ireland, 2009, .
Phillips, DW, Mikhailova, E, Timofejeva, L, Mitchell, JL, Osina, O, Sosnikhina, SP, Jones, RN & Jenkins, G 2008, 'Dissecting meiosis of rye using translational proteomics' Annals of Botany, vol 101, no. 6, pp. 873-880. DOI: 10.1093/aob/mcm202
Jenkins, G, Phillips, DW, Mikhailova, E, Timofejeva, L & Jones, RN 2008, 'Meiotic genes and proteins in cereals' Cytogenetic and Genome Research, vol 120, no. 3-4, pp. 291-301. DOI: 10.1159/000121078
Mikhailova, EI, Phillips, D, Sosnikhina, SP, Lovtsyus, AV, Jones, RN & Jenkins, GM 2006, 'Molecular assembly of meiotic proteins Asy1 and Zyp1 and pairing promiscuity in rye (Secale cereale L.) and its synaptic mutant sy10' Genetics, vol 174, no. 3, pp. 1247-1258. DOI: 10.1534/genetics.106.064105
Jenkins, G, Mikhailova, E, Phillips, D, Hasterok, R, Draper, J & Jones, RN 2005, Models and meiosis in the ’omics era. in Z Zwierzykowski & A Kosmala (eds), Recent advances in genetics and breeding of the grasses. Polish Academy of Sciences, pp. 97-104.