Prof Luis Alejandro Jose Mur

PhD

Prof Luis Alejandro Jose Mur

Professor

Contact Details

Teaching

Research

In my Food Security Research I am interested in developing our understanding of the genetic & biochemical events associated with plant responses to stress & in identifying sources of tolerance/resistance. This work is based on the use of model plant species, Arabidopsis & Brachypodium distachyon & also crops, wheat (Triticum aestivum), oats (Avena sativa) tomato (Solanum esculentum) & barley (Hordeum vulgare).

My interests in clinical health focus on the respiratory tract & identifying drug leads from natural products. Lung cancer (LC) is the most prevalent cancer in the world with 1.3 million deaths recorded each year. Only 15% of patients live for five or more years after initial diagnosis, primarily due to late detection. Chronic obstructive pulmonary disease (COPD) is characterised by an increase in mucus production due to hyperplasia of goblet cells, & hypertrophy of mucus glands COPD is a leading cause of death, arising from acute exacerbations (sudden worsening of symptoms) which may be triggered by infection or environmental pollutants. My research in this area is focusing on the detection of metabolite biomarkers for LC & COPD & investigating possible links with the lung microbiome.

My research in bioactive natural products focus on identifying anti-microbial metabolites against such human pathogens as MSRA & Pseudomonas aeruginosa from invasive plant species & extremophile microbial strains.

I employ cutting edge genomic & post-genomic approaches but will use classical physiological, genetic, biochemical or microbiological approaches- as appropriate. I have numerous national & international collaborations which are supported by funding from the BBSRC, the EU, NSF (USA), DEFRA, Royal Society, Welsh Assembly, &

Publications

Fatty Acid Profile Changes During Gradual Soil Water Depletion in Oats Suggests a Role for Jasmonates in Coping With DroughtSánchez-Martín, J., Canales, F. J., Tweed, J., Lee, M. R. F., Rubiales, D., Gómez-Cadenas, A., Arbona, V., Mur, L. & Prats, E. 2018 In : Frontiers in Plant Science. 1077
Plant species and heavy metals affect biodiversity of microbial communities associated with metal-tolerant plants in metalliferous soilsBorymski, S., Cycoń, M., Beckmann, M., Mur, L. & Piotrowska-Seget, Z. 2018 In : Frontiers in Microbiology.9, 01425
An altered tocopherol composition in chloroplasts reduces plant resistance to Botrytis cinereaCela, J., Tweed, J., Sivakumaran, A., Lee, M. R., Mur, L. & Munné-Bosch, S. 2018 In : Plant Physiology and Biochemistry.127, p. 200-21011 p.
Quantum Cascade Lasers-Based Detection of Nitric OxideMontilla-Bascón, G., Mandon, J., Harren, F. J. M., Mur, L. A. J., Cristescu, S. M. & Prats, E. 2018 Nitric Oxide: Methods and Protocols. Mengel, A. & Lindermayr, C. (eds.). Springer Nature, Vol. 1747, p. 49-579 p. (Methods in Molecular Biology)
Identification and pathogenicity of Fusarium species associated with sesame (Sesamum indicum L.) seeds from the Punjab, PakistanNayyar, B. G., Woodward, S., Mur, L., Akram, A., Arshad, M., Saqlan Naqvi, S. M. & Akhund, S. 2018 In : Physiological and Molecular Plant Pathology.102, p. 128-1358 p.
More publications on the Research Portal