Prof Luis Alejandro Jose Mur


Prof Luis Alejandro Jose Mur


Contact Details



In my Food Security Research I am interested in developing our understanding of the genetic & biochemical events associated with plant responses to stress & in identifying sources of tolerance/resistance. This work is based on the use of model plant species, Arabidopsis & Brachypodium distachyon & also crops, wheat (Triticum aestivum), oats (Avena sativa) tomato (Solanum esculentum) & barley (Hordeum vulgare).

My interests in clinical health focus on the respiratory tract & identifying drug leads from natural products. Lung cancer (LC) is the most prevalent cancer in the world with 1.3 million deaths recorded each year. Only 15% of patients live for five or more years after initial diagnosis, primarily due to late detection. Chronic obstructive pulmonary disease (COPD) is characterised by an increase in mucus production due to hyperplasia of goblet cells, & hypertrophy of mucus glands COPD is a leading cause of death, arising from acute exacerbations (sudden worsening of symptoms) which may be triggered by infection or environmental pollutants. My research in this area is focusing on the detection of metabolite biomarkers for LC & COPD & investigating possible links with the lung microbiome.

My research in bioactive natural products focus on identifying anti-microbial metabolites against such human pathogens as MSRA & Pseudomonas aeruginosa from invasive plant species & extremophile microbial strains.

I employ cutting edge genomic & post-genomic approaches but will use classical physiological, genetic, biochemical or microbiological approaches- as appropriate. I have numerous national & international collaborations which are supported by funding from the BBSRC, the EU, NSF (USA), DEFRA, Royal Society, Welsh Assembly, &


Quantum Cascade Lasers-Based Detection of Nitric OxideMontilla-Bascón, G., Mandon, J., Harren, F. J. M., Mur, L. A. J., Cristescu, S. M. & Prats, E. 2018 Nitric Oxide: Methods and Protocols. Mengel, A. & Lindermayr, C. (eds.). Springer Nature, Vol. 1747, p. 49-579 p. (Methods in Molecular Biology)
Identification and pathogenicity of Fusarium species associated with sesame (Sesamum indicum L.) seeds from the Punjab, PakistanNayyar, B. G., Woodward, S., Mur, L., Akram, A., Arshad, M., Saqlan Naqvi, S. M. & Akhund, S. 2018 In : Physiological and Molecular Plant Pathology.102, p. 128-1358 p.
Target discovery focused approaches to overcome bottlenecks in the exploitation of antimycobacterial natural productsBaptista, R., Bhowmick, S., Nash, R. J., Baillie, L. & Mur, L. 2018 In : Future Medicinal Chemistry.10, 7
A discrete role for alternative oxidase under hypoxia to increase nitric oxide and drive energy productionVishwakarma, A., Kumari, A., Mur, L. & Gupta, K. J. 2018 In : Free Radical Biology and Medicine.
Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824)Baptista, R., Fazakerley, D. M., Beckmann, M., Baillie, L. & Mur, L. A. J. 2018 In : Scientific Reports.8, 1, p. 50841 p., 5084
Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structureGordon, S. P., Contreras-Moreira, B., Woods, D. P., Des Marais, D. L., Burges, D., Shu, S., Stritt, C., Roulin, A. C., Schackwitz, W., Tyler, L., Martin, J., Lipzen, A., Dochy, N., Phillips, J., Barry, K., Geuten, K., Budak, H., Jeunger, T. E., Amasino, R., Caicedo, A. L., Goodstein, D., Davidson, P., Mur, L., Figueroa, M., Freeling, M., Catalán, P. & Vogel, J. P. 2017 In : Nature Communications.8, 2184
The Incidence of Alternaria Species Associated with Infected Sesamum indicum L. Seeds from Fields of the Punjab, PakistanNayyar, B. G., Woodward, S., Mur, L. A. J., Akram, A., Arshad, M., Saqlan Naqvi, S. M. & Akhund, S. 2017 In : The Plant Pathology Journal.33, 6, p. 543-55311 p.
Reduced nitric oxide levels during drought stress promote drought tolerance in barley and is associated with elevated polyamine biosynthesisMontilla-Bascón, G., Rubiales, D., Hebelstrup, K. H., Mandon, J., Harren, F. M., Cristescu, S. M., Mur, L. A. J. & Prats, E. 2017 In : Scientific Reports.7, 1, 13311
Saprotrophic proteomes of biotypes of the witches’ broom pathogen Moniliophthora perniciosaPierre, S., Griffith, G., Morphew, R., Mur, L. & Scott, I. 2017 In : Fungal Biology.121, 9, p. 743-75311 p.
Marker-Assisted Selection for Durable Rust Resistance in a Widely Adopted Wheat Cultivar "Inqilab-91"Awan, S. I., Ahmad, S. D., Mur, L. & Ahmed, M. S. 2017 In : International Journal of Agriculture and Biology.
Favouring NO over H2O2 production will increase Pb tolerance in Prosopis farcta via altered primary metabolismZafari, S., Sharifi, M., Mur, L. & Chashmi, N. A. 2017 In : Ecotoxicology and Environmental Safety.142, p. 293-302
Corrigendum to Metabolomic-based biomarker discovery for non-invasive lung cancer screening: A case study [Biochimica et Biophysica Acta (BBA) – General subjects, vol. 1860 (2016), pp. 2682–2687]O'shea, K., Cameron, S. J., Lewis, K. E., Lewis, P. D., Lu, C. & Mur, L. A. 2017 In : Biochimica et Biophysica Acta (BBA) - General Subjects.
A pilot study using metagenomic sequencing of the sputum microbiome suggests potential bacterial biomarkers for lung cancerCameron, S., Lewis, K. E., Huws, S., Hegarty, M., Lewis, P. D., Pachebat, J. A. & Mur, L. 2017 In : PLoS One. 0177062
An All-Solid-State Phosphate Electrode with H3PO4 Doped Polyaniline as the Sensitive LayerHuang, Y., Ye, Y., Zhao, G., Wu, X., Kan, Y., Mur, L., Han, J. & Qin, H. 2017 In : International Journal of Electrochemical Science.12, 6, p. 4677-4691
Nitric Oxide Has a Concentration-Dependent Effect on the Cell Cycle Acting via EIN2 in Arabidopsis thaliana Cultured CellsNovikova, G. V., Mur, L., Nosov, A. V., Fomenkov, A. A., Mironov, K. S., Mamaeva, A. S., Shilov, E. S., Rakitin, V. Y. & Hall, M. 2017 In : Frontiers in Physiology.8, 142
Moving nitrogen to the centre of plant defence against pathogensMur, L., Simpson, C., Kumari, A., Gupta, A. K. & Gupta, K. J. 2017 In : Annals of Botany.p. 703-7097 p.
Expression of FlHMA3, a vacuolar P1B2-ATPase from Festulolium loliaceum, correlates with response to cadmium stressGuo, Q., Meng, L., Humphreys, M. W., Scullion, J. & Mur, L. A. J. 2017 In : Plant Physiology and Biochemistry.112, p. 270-2778 p.
Linking dynamic phenotyping with metabolite analysis to study natural variation in drought responses of Brachypodium distachyonFisher, L., Han, J., Corke, F., Akinyemi, A., Didion, T., Nielsen, K. K., Doonan, J., Mur, L. & Bosch, M. 2016 In : Frontiers in Plant Science.7, 1751
Compromised Photosynthetic Electron Flow and H2O2 Generation Correlate with Genotype-Specific Stomatal Dysfunctions during Resistance against Powdery Mildew in OatsSánchez-Martín, J., Montilla-Bascón, G., Mur, L. A. J., Rubiales, D. & Prats, E. 2016 In : Frontiers in Plant Science.7, 1660
Ectopic expression and functional characterization of type III polyketide synthase mutants from Emblica officinalis GaertnAiswarya, G., Mallika, V., Mur, L. & Soniya, E. V. 2016 In : Plant Cell Reports.35, 10, p. 2077-209014 p.
Metabolomic-based biomarker discovery for non-invasive lung cancer screening: A case studyO'Shea, K., Cameron, S. J. S., Lewis, K. E., Lewis, P. D., Lu, C. & Mur, L. A. J. 2016 In : Biochimica et Biophysica Acta (BBA) - General Subjects.1860, 11 (Part B), p. 2682-26876 p.
Taxon interactions control the distributions of cryoconite bacteria colonizing a High Arctic ice capGokul, J., Hodson, A. J., Saetnan, E., Irvine-Fynn, T., Westall, P. J., Detheridge, A., Takeuchi, N., Bussell, J., Mur, L. & Edwards, A. 2016 In : Molecular Ecology.25, 15, p. 3752-376716 p.
Metabolome-mediated biocryomorphic evolution promotes carbon fixation in Greenlandic cryoconite holesCook, J. M., Edwards, A., Bulling, M., Mur, L. A. J., Cook, S., Gokul, J. K., Cameron, K. A., Sweet, M. & Irvine-Fynn, T. D. L. 2016 In : Environmental Microbiology.18, Thematic Issue, p. 4674-4686
Terminator Operon Reporter: Combining a transcription termination switch with reporter technology for improved gene synthesis and synthetic biology applicationsZampini, M., Mur, L., Rees Stevens, P., Pachebat, J. A., Newbold, C., Hayes, F. & Kingston-Smith, A. 2016 In : Scientific Reports.6, 26572
ABA Suppresses Botrytis cinerea Elicited NO Production in Tomato to Influence H2O2 Generation and Increase Host SusceptibilitySivakumaran, A., Akinyemi, A., Mandon, J., Cristescu, S. M., Hall, M., Harren, F. J. M. & Mur, L. 2016 In : Frontiers in Plant Science.7, 709
The metabolomic detection of lung cancer biomarkers in sputumCameron, S., Lewis, K. E., Beckmann, M., Allison, G., Ghosal, R., Lewis, P. D. & Mur, L. 2016 In : Lung Cancer.94, p. 88-958 p.
Metagenomic Sequencing of the Chronic Obstructive Pulmonary Disease Upper Bronchial Tract Microbiome Reveals Functional Changes Associated with Disease SeverityCameron, S., E. Lewis, K., Huws, S., Lin, W., Hegarty, M., D. Lewis, P., Mur, L. & Pachebat, J. A. 2016 In : PLoS One.11, 2, 0149095
Project Report No. 557: Screening for 'costs of disease resistance'James, L., Smith, J., Paveley, N., Mur, L. & Brown, J. 2016 Agriculture and Horticulture Development Board. 92 p.
Laser-Based Methods for Detection of Nitric Oxide in PlantsMandon, J., Mur, L. A. J., Harren, F. J. M. & Cristescu, S. M. 2016 Plant Nitric Oxide: Methods and Protocols. Gupta, K. J. (ed.). Springer Nature, p. 113-12614 p. (Methods in Molecular Biology; vol. 1242)
Modulation of Pb-induced stress in Prosopis shoots through an interconnected network of signaling molecules, phenolic compounds and amino acidsZafari, S., Sharifi, M., Chashmi, N. A. & Mur, L. 2015 In : Plant Physiology and Biochemistry.99, p. 11-2010 p.
The development of tea blister caused by Exobasidium vexans in tea (Camellia sinensis) correlates with the reduced accumulation of some antimicrobial metabolites and the defence signals salicylic and jasmonic acidsMur, L., Hauck, B., Winters, A., Heald, J. K., Lloyd, A. J., Chakraborty, U. & Chakraborty, B. N. 2015 In : Plant Pathology.64, 6, p. 1471-1483
Senescence and programmed cell deathThomas, H., Ougham, H., Mur, L. & Jansson, S. 2015 Biochemistry and Molecular Biology of Plants. Buchanan, B. B., Gruissem, W. & Jones, R. L. (eds.). Wiley, p. 925-982
The human salivary microbiome exhibits temporal stability in bacterial diversityCameron, S. J. S., Huws, S., Hegarty, M. J., Smith, D. P. M. & Mur, L. A. J. 2015 In : FEMS Microbiology Ecology.91, 9, fiv091
Regulatory role of nitric oxide in plantsMamaeva, A. S., Fomenkov, A. A., Nosov, A. V., Moshkov, I. E., Mur, L. A. J., Hall, M. A. & Novikova, G. V. 2015 In : Russian Journal of Plant Physiology (Fiziologiya rastenii).62, 4, p. 427-44014 p.
RapGene: a fast and accurate strategy for synthetic gene assembly in Escherichia coliZampini, M., Rees Stevens, P., Pachebat, J., Kingston-Smith, A., Mur, L. & Hayes, F. 2015 In : Scientific Reports.5, 11302
Genome-wide association study for crown rust (Puccinia coronata f. sp. avenae) and powdery mildew (Blumeria graminis f. sp. avenae) resistance in an oat (Avena sativa) collection of commercial varieties and landracesMontilla-Bascón, G., Rispail, N., Sánchez-Martín, J., Rubiales, D., Mur, L. A. J., Langdon, T., Howarth, C. J. & Prats, E. 2015 In : Frontiers in Plant Science.6, 103
Ethylene, Nitric Oxide and Haemoglobins in Plant Tolerance to FloodingMur, L., Gupta, K. J., Chakraborty, U., Chakraborty, B. & Hebelstrup, K. H. 2015 Abiotic Stresses in Crop Plants. Chakraborty, U. & Chakraborty, B. (eds.). CABI Publishing, p. 43-5311 p.
The effect of resistance to mildew infection on ruminal fermentation of Lolium perenneClaes, J., Davies, T., Rees Stevens, P., Wilkinson, T., Mur, L. & Kingston-Smith, A. 2014 EGF at 50: The future of European grasslands. Proceedings of the 25th General Meeting of the European Grassland Federation, Aberystwyth, Wales, 7-11 September 2014. : Grassland Science in Europe. Hopkins, A. (ed.). Prifysgol Aberystwyth | Aberystwyth University, Vol. 19, p. 849851 p.
Coupled cryoconite ecosystem structure–function relationships are revealed by comparing bacterial communities in alpine and Arctic glaciersEdwards, A., Mur, L., Girdwood, S., Anesio, A. M., Stibal, M., Edwards Rassner, S., Hell, K., Pachebat, J., Post, B., Bussell, J. S., Cameron, S., Griffith, G., Hodson, A. J. & Sattler, B. 2014 In : FEMS Microbiology Ecology.89, 2, p. 222-23715 p.
Effects of bovine colostrum supplementation on upper respiratory illness in active malesJones, A. W., Cameron, S. J. S., Thatcher, R., Beecroft, M. S., Mur, L. A. J. & Davison, G. 2014 In : Brain, Behavior, and Immunity.39, p. 194-203
Guarding the guard cells?Gupta, K. J., Mur, L. A. J. & Ratcliffe, R. G. 2014 In : New Phytologist.203, 2, p. 349-3513 p.
Update on the genomics and basic biology of Brachypodium: International Brachypodium Initiative (IBI)Catalan, P., Chalhoub, B., Chochois, V., Garvin, D. F., Hasterok, R., Manzaneda, A. J., Mur, L. A. J., Pecchioni, N., Rasmussen, S. K., Vogel, J. P. & Voxeur, A. 2014 In : Trends in Plant Science.19, 7, p. 414-4185 p.
Revealing the Molecular and Physiological Responses to Water Deficit in the Bioenergy Crop Miscanthus x giganteusIngs, J., Mur, L. A. J., Clifton-Brown, J. C., Bosch, M. & Robson, P. R. 2014 p. 34
Trichoderma asperelloides suppresses nitric oxide generation elicited by Fusarium oxysporum in Arabidopsis roots.Gupta, K. J., Mur, L. A. J. & Brotman, Y. 2014 In : Molecular Plant-Microbe Interactions.27, 4, p. 307-3148 p.
A metabolomic study in oats (Avena sativa) highlights a drought tolerance mechanism based on salicylate signalling pathways and the modulation of carbon, antioxidant and photo-oxidative metabolismSanchez-Martin, J., Heald, J., Kingston-Smith, A., Winters, A., Rubiales, D., Sanz, M., Mur, L. & Prats, E. 2014 In : Plant, Cell and Environment.
Genetic Diversity and Population Structure Among Oat Cultivars and LandracesMontilla-Bascón, G., Sánchez-Martín, J., Rispail, N., Rubiales, D., Mur, L., Langdon, T., Griffiths, I., Howarth, C. & Prats, E. 2013 In : Plant Molecular Biology Reporter.31, 6, p. 1305-1314
Stomatal lock-up following pathogenic challenge: Source or symptom of costs of resistance in crops?Mur, L. A. J., Simpson, C., Gay, A., Paveley, N., Sanchez-Martin, J. & Prats, E. 2013 In : Plant Pathology.62, S1, p. 72-8211 p.
Comparative Metabolite Fingerprinting of the Rumen System during Colonisation of Three Forage Grass (Lolium perenne L.) VarietiesKingston-Smith, A. H., Davies, T., Rees Stevens, P. & Mur, L. A. J. 2013 In : PLoS One.8, 11, e82801
Physiological and growth responses to water deficit in the bioenergy crop Miscanthus x giganteusIngs, J., Mur, L. A. J., Robson, P. R. H. & Bosch, M. 2013 In : Frontiers in Plant Science.4, p. 468
An assessment of the biotechnological use of hemoglobin modulation in cerealsHebelstrup, K. H., Shah, J. K., Simpson, C., Schjoerring, J. K., Mandon, J., Cristescu, S. M., Harren, F. J. M., Christiansen, M. W., Mur, L. A. J. & Igamberdiev, A. U. 2013 In : Physiologia Plantarum.
Striking a balance:does nitrate uptake and metabolism regulate both NO generation and scavenging?Mur, L. A. J., Hebelstrup, K. H. & Gupta, K. J. 2013 In : Frontiers in Plant Science.4, 288
Comparison of cell wall composition across 15 ecotypes of Brachypodium distachyon originating from the eastern and western MediterraneanAllison, G. G., Johnson, J., Poncon, C. & Mur, L. A. J. 2013
Exploiting Brachypodium to Identify Cell Wall-Specific Responses to DroughtFisher, L., Mur, L. A. J., Didion, T., Nielsen, K. K. & Bosch, M. 2013 p. S4.4
Spectroscopic monitoring of NO traces in plants and human breath: applications and perspectivesCristescu, S. M., Marchenko, D., Mandon, J., Hebelstrup, K. H., Griffith, G. W., Mur, L. A. J. & Harren, F. J. M. 2013 In : Applied Physics B: Lasers and Optics.110, 2, p. 203-2119 p.
Nitric oxide in plants an assessment of the current state of knowledgeMur, L. A. J., Mandon, J., Persijn, S., Cristescu, S. M., Moshkov, I. E., Novikova, G. V., Hall, M., Harren, F. J. M., Hebelstrup, K. H. & Gupta, K. J. 2013 In : AoB PLANTS.5, pls052
The form of nitrogen nutrition affects resistance against Pseudomonas syringae pv. phaseolicola in tobaccoGupta, K. J., Brotman, Y., Segu, S., Zeier, T., Zeier, J., Persijn, S. T., Cristescu, S. M., Harren, F. J. M., Bauwe, H., Fernie, A. R., Kaiser, W. M. & Mur, L. A. J. 2013 In : Journal of Experimental Botany.64, 2, p. 553-56816 p.
Integrating nitric oxide into salicylic acid and jasmonic acid/ ethylene plant defense pathwaysMur, L. A. J., Prats, E., Pierre, S., Hall, M. & Hebelstrup, K. H. 2013 In : Frontiers in Plant Science.4, 215
Exploring the mechanisms behind the effects of chronic bovine colostrum supplementation on risk of upper respiratory tract infectionJones, A. W., Cameron, S. J., Thatcher, R., Beecroft, M. S., Mur, L. & Davison, G. 2013
Haemoglobin modulates salicylate and jasmonate/ethylene-mediated resistance mechanisms against pathogensMur, L. A. J., Sivakumaran, A., Mandon, J., Cristescu, S. M., Harren, F. J. M. & Hebelstrup, K. H. 2012 In : Journal of Experimental Botany.63, 12, p. 4375-438713 p.
Commentary - NO and ROS homeostasis in mitochondria: a central role for alternative oxidaseGupta, K. J., Kapuganti, J., Igamberdiev, A. U. & Mur, L. A. J. 2012 In : New Phytologist.195, 1, p. 1-33 p.
Nitric oxide counters ethylene effects on ripening fruitsManjunatha, G., Gupta, K. J., Lokesh, V., Mur, L. A. J. & Neelwarne, B. 2012 In : Plant Signaling and Behavior.7, 4, p. 476-4838 p.
Evidence of a role for foliar salicylic acid in regulating the rate of post-ingestive protein breakdown in ruminants and contributing to landscape pollutionKingston-Smith, A. H., Davies, T. E., Edwards, J. E., Gay, A. & Mur, L. A. J. 2012 In : Journal of Experimental Botany.63, 8, p. 3243-325513 p.
A novel function for a redox-related LEA protein (SAG21/AtLEA5) in root development and biotic stress responsesSalleh, F. M., Evans, K., Goodall, B., Machin, H., Mowla, S. B., Mur, L. A. J., Runions, J., Theodoulou, F. L., Foyer, C. H. & Rogers, H. J. 2012 In : Plant, Cell and Environment.35, 2, p. 418-42912 p.
Evolution and taxonomic split of the model grass Brachypodium distachyonCatalán, P., Müller, J., Hasterok, R., Jenkins, G., Mur, L. A. J., Langdon, T., Betekhtin, A., Siwinska, D., Pimentel, M. & López-Alvarez, D. 2012 In : Annals of Botany.109, 2, p. 385-40521 p.
Separating the inseparable: The metabolomic analysis of plant-pathogen interactionsAllwood, J. W., Heald, J., Lloyd, A. J., Goodacre, R. & Mur, L. A. J. 2012 Plant Metabolomics : Methods and Protocols. Hardy, N. W. & Hall, R. D. (eds.). (Methods in Molecular Biology)
Haemoglobin modulates NO emission and hyponasty under hypoxia-related stress in Arabidopsis thalianaHebelstrup, K. H., van Zanten, M., Mandon, J., Voesenek, L. A. C. J., Harren, F. J. M., Cristescu, S. M., Møller, I. M. & Mur, L. A. J. 2012 In : Journal of Experimental Botany.63, 15, p. 5581-559111 p.
Targeting sources of drought tolerance within an Avena spp. collection through multivariate approachesSánchez-Martín, J., Mur, L. A. J., Rubiales, D. & Prats, E. 2012 In : Planta.236, 5, p. 1529-154517 p.
Latent soil effects of grazing and ammonium deposition on Deschampsia flexuosa tillers inserted and grown in heather moorland soilJones, R. J., Causton, D. R., Emmett, B., Mur, L. A. J. & Gwynn-Jones, D. 2012 In : Environmental and Experimental Botany.81, p. 72-787 p.
Plant hemoglobins: important playersat the crossroads between oxygen and nitric oxideGupta, K. J., Hebelstrup, K. H., Mur, L. A. J. & Igamberdiev, A. U. 2011 In : FEBS Letters.585, 24, p. 3843-38497 p.
Evaluation of FTIR Spectroscopy as a diagnostic tool for lung cancer using sputumLewis, P. D., Lewis, K. E., Ghosal, R., Bayliss, S., Lloyd, A. J., Wills, J., Godfrey, R., Kloer, P. & Mur, L. A. J. 2011 In : BMC Cancer.10, 640, 640
Brachypodium as a model for the grasses: Today and the futureBrkljacic, J., Grotewold, E., Scholl, R., Mockler, T. C., Garvin, D. F., Vain, P., Brutnell, T., Sibout, R., Bevan, M., Budak, H., Caicedo, A. L., Gao, C., Gu, Y-Q. Q., Hazen, S. P., Holt III, B. F., Hong, S-Y., Jordan, M., Manzaneda, A. J., Mitchell-Olds, T., Mochida, K., Mur, L. A. J., Park, C-M., Sedbrook, J., Watt, M., Zheng, S. J. & Vogel, J. P. 2011 In : Plant Physiology.157, 1, p. 3-1311 p.
Metabolomic approaches indicate that cell wall modifications play a major role in ethylene-mediated resistance against Botrytis cinereaLloyd, A. J., Allwood, J. W., Winder, C. L., Dunn, W. B., Heald, J. K., Cristescu, S. M., Sivakumaran, A., Harren, F. J. M., Mulema, J., Denby, K., Goodacre, R., Smith, A. R. & Mur, L. A. J. 2011 In : Plant Journal.67, 5, p. 852-86817 p.
Nitric oxide, nitrate reductase and UV-B toleranceGupta, K. J., Bauve, H. & Mur, L. A. J. 2011 In : Tree Physiology.31, 8, p. 795-7973 p.
Exploiting the Brachypodium Tool Box in cereal and grass researchMur, L. A. J., Allainguillaume, J., Catalán, P., Hasterok, R., Jenkins, G., Lesniewska, K., Thomas, I. & Vogel, J. P. 2011 In : New Phytologist.191, 2, p. 334-34714 p.
Are stomatal responses the key to understanding the cost of fungal disease resistance in plants?Gay, A. P., Mur, L. A. J. & Withers, C. M. 2011 In : Journal of the Science of Food and Agriculture.91, 9, p. 1538-15403 p.
Morphological classification of plant cell deathsvan Doorn, W. G., Beers, E. P., Dangl, J. L., Franklin-Tong, V. E., Gallois, P., Hara-Nishimura, I., Jones, A. M., Kawai-Yamada, M., Lam, E., Mundy, J., Mur, L. A. J., Petersen, M., Smertenko, A., Taliansky, M., Van Breusegem, F., Wolpert, T., Woltering, E., Zhivotovsky, B. & Bozhkov, P. V. 2011 In : Cell Death and Differentiation.18, 8, p. 1241-12466 p.
Methods of nitric oxide detection in plants: A commentaryMur, L. A. J., Mandon, J., Cristescu, S. M., Harren, F. J. M. & Prats, E. 2011 In : Plant Science.181, 5, p. 509-51911 p.
Brachypodium as a model for studying traits relevant for the development of bioenergy grassesBosch, M., Roberts, L. A., Dalton, S. J., Robson, P. R., Donnison, I. S., Nielsen, K. & Mur, L. A. J. 2011 p. Abstract No: P2.9
Using Fourier Transform Infra-Red (FTIR) on sputum to develop a predictive model to differentiate lung cancer from healthy controlsLewis, K. E., Ghosal, R., Mur, L. A. J., Bayliss, S., Kloer, P. & Lewis, P. 2011 In : American Journal of Respiratory and Critical Care Medicine.183, p. Paper A6098
Accumulation of chlorophyll catabolites photosensitizes the hypersensitive response elicited by Pseudomonas syringae in ArabidopsisMur, L. A. J., Aubry, S., Mondhe, M., Kingston-smith, A., Gallagher, J., Timms-taravella, E., James, C., Papp, I., Hörtensteiner, S., Thomas, H. & Ougham, H. 2010 In : New Phytologist.188, 1, p. 161-17414 p.
Dual metabolomics: A novel approach to understanding plant-pathogen interactionsAllwood, J. W., Clarke, A., Goodacre, R. & Mur, L. A. J. 2010 In : Phytochemistry.71, 5-6, p. 590-5978 p.
Blumeria graminis interactions with barley conditioned by different single R genes demonstrate a temporal and spatial relationship between stomatal dysfunction and cell deathPrats, E., Gay, A. P., Roberts, P. C., Thomas, B. J., Sanderson, R., Paveley, N., Lyngkjaer, M. F., Carver, T. L. W. & Mur, L. A. J. 2010 In : Phytopathology.100, 1, p. 21-3212 p.
Fourier transform infra-red (FTIR) spectroscopy on sputum from lung cancer patients, healthy controls and a high-risk cohortGhosal, R., Lewis, K. E., Kloer, P., Bayliss, S., Mur, L. A. J. & Lewis, P. D. 2010 British Thoracic Society Winter Meeting 2010.p. A19-A20
NO way to treat a coldHinch, D. K., Gupta, K. J. & Mur, L. A. J. 2010 In : New Phytologist.189, 2, p. 360-3634 p.
Proteomic analysis of the cacao pathogen Moniliophthora perniciosaPierre, S., Mur, L. A. J., Morphew, R., Hamilton, J., Scott, I. M. & Griffith, G. W. 2009
Identification of genes involved in the floral transition at the shoot apical meristem of Lolium perenne L. by use of suppression subtractive hybridisationMur, L. A. J., Donnison, I. S., Milbourne, D., Guiney, E., Byrne, S. & Barth, S. 2009 In : Plant Growth Regulation.59, 3, p. 215-22511 p.
Biphasic ethylene production during the hypersensitive response in Arabidopsis: A window into defence priming mechanisms?Mur, L. A. J., Lloyd, A. J., Cristescu, S. M., Harren, F. J. M., Hall, M. & Smith, A. 2009 In : Plant Signaling and Behavior.4, 7, p. 610-6134 p.
The phytohormone salicylic acid influences autolysis in ruminantingested plant cellsKingston-Smith, A., Davies, T., Kyme, E. & Mur, L. 2009 In : Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology.153, 2 (Supplement), S160
Aspirin, salicylates and cancerElwood, P. C., Gallagher, A. M., Duthie, G. G., Mur, L. A. J. & Morgan, G. 2009 In : The Lancet.373, 9671, p. 1301-13099 p.
Jasmonates interact with salicylic acid to confer basal thermotolerance in Arabidopsis thalianaClarke, S. M., Cristescu, S. M., Miersch, O., Harren, F. J. M., Wasternack, C. & Mur, L. A. J. 2009 In : New Phytologist.182, 1, p. 175-18713 p.
Identification of coincident QTL for days to heading, spike length and spikelets per spike in Lolium perenne L.Byrne, S., Guiney, E., Barth, S., Donnison, I. S., Mur, L. A. J. & Milbourne, D. 2009 In : Euphytica.166, 1, p. 61-7010 p.
Proteomic approaches to characterise the role of ethylene in tomato plants attached by Botrytis cinereaSivakumaran, A., Mur, L. A. J. & Smith, A. R. 2009 p. p24
Fourier transform infrared spectroscopy and metabolic profiling in lung cancerKloer, P., Ghosal, R., Mur, L. A. J., Lewis, K. E. & Lewis, P. D. 2008 Winter Meeting of the British-Thoracic-Society.p. A60-A61
Nitric oxide interacts with salicylate to regulate biphasic ethylene production during the hypersensitive responseMur, L. A. J., Laarhoven, L. J. J., Harren, F. J. M., Hall, M. & Smith, A. R. 2008 In : Plant Physiology.148, 3, p. 1537-154610 p.
The control of chlorophyll catabolism and the status of yellowing as a biomarker of leaf senescenceOugham, H. J., Hortensteiner, S., Armstead, I. P., Donnison, I. S., King, I. P., Thomas, H. & Mur, L. A. J. 2008 In : Plant Biology.10, S1, p. 4-1411 p.
Nitric oxide generation in Vicia faba phloem cells reveals them to be sensitive detectors as well as possible systemic transducers of stressGaupels, F., Furch, A. C. U., Will, T., Mur, L. A. J., Kogel, K-H. & Van Bel, A. J. E. 2008 In : New Phytologist.178, 3, p. 634-64613 p.
Pathogen-derived nitric oxide influences formation of the appressorium infection structure in the phytopathogenic fungus Blumeria graminisPrats, E., Carver, T. L. W. & Mur, L. A. J. 2008 In : Research in Microbiology.159, 6, p. 476-4805 p.
Using Fourier transform infrared (FTIR) spectroscopy to evaluate metabolic markers in sputum in patients with and without lung cancerMur, L. A. J. 2008 p. S11-S11
Development of genetic and genomic research resources for Brachypodium distachyon, a new model system for grass crop researchGarvin, D. F., Mur, L. A. J., Hasterok, R., Jenkins, G. M., Gu, Y-Q. Q., Hazen, S. P., Mockler, T. C. & Vogel, J. P. 2008 In : Crop Science.48, Supplement 1, p. S69-S84
The hypersensitive response; the centenary is upon us but how much do we know?Mur, L. A. J., Kenton, P., Lloyd, A. J., Ougham, H. J. & Prats, E. 2007 In : Journal of Experimental Botany.59, 3, p. 501-52020 p.
Enemy at the Gates: Interaction-Specific Stomatal Responses to Pathogenic ChallengePrats, E., Carver, T. L. W., Gay, A. & Mur, L. 2007 In : Plant Signaling and Behavior.2, 4, p. 275-277
The application of MANOVA to analyse Arabidopsis thaliana metabolomic data from factorially designed experimentsJohnson, H. E., Smith, A. R., Mur, L. A. J., Causton, D. R. & Lloyd, A. J. 2007 In : Metabolomics.p. 517-53014 p.
Post-ingestion induction of plant cell death: Regulation and implicationsKingston-Smith, A. H., Davies, T. & Mur, L. A. J. 2007 p. 200-
NO provides mainly avr-dependent inputs into cell death mechanisms associated with the hypersensitive response in tobaccoHarren, F. J. M., Mur, L. A. J., Kenton, P., Smith, A. & Laarhoven, L. 2007 In : Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology.146, 4, p. S256
Throwing new light on the hypersensitive responseMur, L., Mondhe, M., Papp, I., Holton, N., Hoertensteiner, S., Kingston-Smith, A., Thomas, H. & Ougham, H. 2007 In : Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology.146, 4, C2.9
Metabolomic approaches to understand ethylene mediated defenses in Arabidopsis thaliana against Botrytis cinereaLloyd, A. J., Smith, A. R. & Mur, L. A. J. 2007 Advances in Plant Ethylene Research. Ramina, A., Chang, C., Giovannoni, J., Klee, H., Perata, P. & Woltering, E. (eds.). Dordrecht: Springer Nature, p. 359-368 77
NO way to live: the various roles of nitric oxide in plant-pathogen interactionsMur, L. A. J., Carver, T. L. W. & Prats, E. 2006 In : Journal of Experimental Botany.57, 3, p. 489-50517 p.
Stomatal lock-open, a consequence of epidermal cell death, follows transient suppression of stomatal opening in barley attacked by Blumeria graminisPrats, E., Gay, A. P., Thomas, B. J., Mur, L. A. J. & Carver, T. L. W. 2006 In : Journal of Experimental Botany.p. 2211-222616 p.
Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory non-polar metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea.Mur, L. A. J., Heald, J. K., Allwood, J. W., Goodacre, R. & Ellis, D. I. 2006 In : Plant Journal.p. 351-36818 p.
The outcomes of concentration-specific interactions between salicylate and jasmonate signaling include synergy, antagonism, and oxidative stress leading to cell deathAtzorn, R., Mur, L. A. J., Wasternack, C., Kenton, P. & Miersch, O. 2005 In : Plant Physiology.140, 1, p. 249-26214 p.
Harpin modulates the accumulation of salicylic acid by Arabidopsis cells via apoplastic alkalizationMur, L. A. J., Clarke, A., Kenton, P. & Darby, R. M. 2005 In : Journal of Experimental Botany.p. 3129-31368 p.
Laser photoacoustic detection allows in planta detection of nitric oxide in tobacco following challenge with avirulent and virulent pseudomonas syringae pathovarsHarren, F. J. M., Smith, A. R., Laarhoven, L. J. J., Holton, N. J., Mur, L. A. J. & Santosa, I. E. 2005 In : Plant Physiology.138, 3, p. 1247-125812 p.
In planta measurements of oxidative bursts elicited by avirulent and virulent bacterial pathogens suggests that H2O2 is insufficient to elicit cell death in tobaccoDraper, J. H., Kenton, P. & Mur, L. A. J. 2005 In : Plant, Cell and Environment.p. 548-56114 p.
Nitric oxide contributes both to papilla-based resistance and the hypersensitive response in barley attacked by Blumeria graminis f. sp.hordeiPrats, E., Mur, L. A. J., Sanderson, R. & Carver, T. L. W. 2005 In : Molecular Plant Pathology.6, 1, p. 65-7814 p.
The investigation of flowering control in late/rare flowering Lolium perenneGuiney, E., Byrne, S., Donnison, I. S., Mur, L. A. J. & Humphreys, M. O. (ed.) 2005
Magnaporthe grisea interactions with the model grass Brachypodium distachyon closely resemble those with rice (Oryza sativa)Routledge, A. P. M., Draper, J. H., Talbot, N. J., Smith, J. V., Mur, L. A. J. & Shelley, G. 2004 Molecular Plant Pathology.Wiley, p. 253-26513 p.
The AoPR10 promoter and certain endogenous PR10 genes respond to oxidative signals in ArabidopsisFarrell, G. G., Sturgess, F. J., Mur, L. A. J. & Draper, J. H. 2004 In : Molecular Plant Pathology.p. 267-28014 p.
Powdery mildew, cereal cells and sustainable crop productionCarver, T. L. W., Prats, E., Gay, A., Mur, L., Thomas, B. J. & Kunoh, H. 2004
Prospects for functional genomics in a new model grassJenkins, G., Mur, L., Bablak, P., Hasterok, R. & Draper, J. 2004 Plant Functional Genomics. Leister, D. (ed.). Taylor & Francis
A mutation in the Cap Binding Protein 20 gene confers drought tolerance to ArabidopsisDalmadi, A., Koncz, C., Mur, L. A. J., Papp, I. & Dulai, S. 2004 In : Plant Molecular Biology.p. 679-6868 p.
Characterization of a proteinase inhibitor from Brachypodium distachyon suggests the conservation of defence signalling pathways between dicotyledonous plants and grassesStoddart, W. M., Xu, R. L., Routledge, A. P. M., Draper, J. H., Casson, S. A. & Mur, L. A. J. 2004 In : Molecular Plant Pathology.5, 4, p. 267-28014 p.
Salicylate accumulation inhibits growth at chilling temperature in ArabidopsisScott, I. M., Clarke, S. M., Wood, J. E. & Mur, L. A. J. 2004 In : Plant Physiology.135, 2, p. 1040-104910 p.
Salicylic acid dependent signaling promotes basal thermotolerance but is not essential for acquired thermotolerance in Arabidopsis thalianaClarke, S. M., Mur, L. A. J., Wood, J. E. & Scott, I. M. 2004 In : Plant Journal.38, 3, p. 432-44716 p.
Ethylene regulates monomeric GTP-binding protein gene expression and activity in ArabidopsisHall, M., Moshkov, I. E., Mur, L. A. J., Novikova, G. V. & Smith, A. R. 2003 In : Plant Physiology.131, 4, p. 1705-171713 p.
Ethylene rapidly up-regulates the activities of both monomeric GTP-binding proteins and protein kinase(s) in epicotyls of peaMoshkov, I. E., Hall, M., Novikova, G. V., Smith, A. R. & Mur, L. A. J. 2003 In : Plant Physiology.p. 1718-17269 p.
Protein kinases in plants in the transduction of abiotic and biotic signalsHall, M., Novikova, G. V., Moshkov, I. E., Mur, L. A. J. & Smith, A. R. 2002 In : Russian Journal of Plant Physiology (Fiziologiya rastenii).49, 1, p. 107-11913 p.
Brachypodium distachyon. A new model system for functional genomics in grassesBablak, P., Jenkins, G. M., Ghosh-Biswas, G. C., Routledge, A. P. M., Mur, L. A. J., Draper, J. H. & Hasterok, R. 2001 In : Plant Physiology.p. 1539-155517 p.
Ethylene signal perception and transduction: multiple paradigms?Moshkov, I. E., Smith, A. R., Novikova, G. V., Mur, L. A. J. & Hall, M. 2001 In : Biological Reviews.76, 1, p. 103-1086 p.
A loss of resistance to avirulent bacterial pathogens in tobacco is associated with the attenuation of a salicylic acid-potentiated oxidative burstMur, L., Brown, I. R., Darby, R., Bestwick, C. S., Bi, Y-M., Mansfield, J. W. & Draper, J. 2000 In : Plant Journal.23, 5, p. 309-621