Prof William Haresign BSc, PhD Nottingham

Prof William Haresign

Emeritus Professor

Contact Details

Profile

Will obtained a BSc in Animal Science from the University of Nottingham in 1971. He then studied for a PhD in Animal Physiology at Nottingham, undertaking research on the induction of out-of-season breeding in sheep, before being appointed to a Lectureship in Animal Production in 1974. He was subsequently promoted to Senior Lecturer in Animal Production in 1988 and to Reader in Animal Production in 1994, before transferring to the Institute of Rural Sciences (now IBERS), Aberystwyth University in 1996 as Professor of Agriculture.

Research

Will has undertaken a considerable volume of research work on sheep reproduction, sheep breeding, the development of AI and embryo transfer in sheep. Since moving to Aberystwyth, he has established a Wales Spin-Out company, CBS Technologies (now trading as Innovis), which now provides AI, embryo transfer, scrapie genotyping, ultrasound scanning of carcass composition and general breeding advice to the UK sheep industry.

Publications

2015

Beynon, S.E., Slavov, G.T., Farré-Belmonte, M., Sunduimijid, B., Waddams, K., Davies, B., Haresign, W., Kijas, J., Macleod, I.M., Newbold, C.J., Davies, L., Larkin, D.M. 2015. Population structure and history of the Welsh sheep breeds determined by whole genome genotyping. BMC Genetics 16 (1) 65 10.1186/s12863-015-0216-x Other Cadair

Huson, K.M., Haresign, W., Hegarty, M., Blackmore, T., Potter, C., McEwan, N. 2015. Assessment of Genetic Relationship between Six Populations of Welsh Mountain Sheep using Microsatellite Markers. Czech Journal of Animal Science 60 (5) pp. 216-223. 10.17221/8171-CJAS Cadair

2014

Foulds, S.A., Brewer, P.A., Macklin, M.G., Haresign, W., Betson, R.E., Edwards Rassner, S.M. 2014. Flood-related contamination in catchments affected by historical metal mining: an unexpected and emerging hazard of climate change. Science of the Total Environment 476-477 pp. 165-180. 10.1016/j.scitotenv.2013.12.079 Cadair

Christensen, A.C.M., Haresign, W., Khalid, M. 2014. Progesterone exposure of seasonally anoestrous ewes alters the expression of angiogenic growth factors in preovulatory follicles. Theriogenology 81 (2) pp. 358-367. 10.1016/j.theriogenology.2013.10.005 Cadair

Macfarlane, J.M., Lamb, N.R., Matika, O., Johnson, P.L., Wolf, B.T., Haresign, W., Bishop, S.C., Bunger, L. 2014. Effect of mode of action of the Texel Muscling QTL (TM-QTL) on carcass traits in purebred Texel lambs. Animal 8 (7) pp. 1053-1061. 10.1017/S1751731114001104 Cadair

2013

Marquez, G.C., Haresign, W., Davies, M.H., Notter, D.R., Rhoehe, R., Bunger, L., Simm, G., Lewis, R.M. 2013. Genetic evaluation of days to harvest in crossbred lambs. Journal of Animal Science 91 (11) pp. 5153-5160. 10.2527/jas.2012-6093

Marquez, G.C., Haresign, W., Davies, M.H., Roehe, R., Bunger, L., Simm, G., Lewis, R.M. 2013. Index selection in terminal sires improves lamb performance at finishing. Journal of Animal Science 91 (1) pp. 38-43. 10.2527/jas.2012-5383 Cadair

2012

Macfarlane, J.M., Lambe, N.R., Haresign, W., Bunger, L. 2012. The effect of the Texel Muscling QTL on live and carcass weight in Texel lambs. Small Ruminant Research 105 (1-3) pp. 117-121. 10.1016/j.smallrumres.2012.02.011i Cadair

Christensen, A.C.M., Haresign, W., Khalid, M. 2012. Progesterone exposure of the preovulatory follicle in the seasonally anestrous ewe alters the expression of angiogenic growth factors in the early corpus luteum. Theriogenology 77 (8) pp. 1648-1660. 10.1016/j.theriogenology.2011.12.010 Cadair

Perry, K., Haresign, W., Wathes, D.C., Pitsillides, A.A., Khalid, M. 2012. Cervical expression of hyaluronan synthases varies with the stage of the estrous cycle in the ewe. Theriogenology 77 (6) pp. 1100-1110. 10.1016/j.theriogenology.2011.10.012 Cadair

Marquez, G.C., Haresign, W., Davies, M.H., Emmans, G.C., Roehe, R., Bunger, L., Simm, G., Lewis, R.M. 2012. Index selection in terminal sires improves early lamb growth. Journal of Animal Science 90 (1) pp. 142-151. 10.2527/jas.2011-4294 Cadair

Craigie, C.R., Lambe, N.R., Richardson, R.I., Haresign, W., Maltin, C.A., Rehfeldt, C., Roehe, R., Morris, S.T., Bunger, L. 2012. The effect of sex on some carcass and meat quality traits in Texel ewe and ram lambs. Animal Production Science 52 (6-7) pp. 601-607. 10.1071/AN11282 Cadair

2011

Lambe, N.R., Richardson, R.I., Macfarlane, J.M., Nevison, I., Haresign, W., Matika, O., Bunger, L. 2011. Genotypic effects of the Texel Muscling QTL (TM-QTL) on meat quality in purebred Texel lambs. Meat Science 89 (2) pp. 125-132. 10.1016/j.meatsci.2011.03.014 Cadair

Masri, A.Y., Lambe, N.R., Macfarlane, J.M., Brotherstone, S., Haresign, W., Bunger, L. 2011. Evaluating the effects of the c.*1232G > A mutation and TM-QTL in Texel x Welsh Mountain lambs using ultrasound and video image analysis. Small Ruminant Research 99 (2-3) pp. 99-109. 10.1016/j.smallrumres.2011.03.047 Cadair

Matheson, S.M., Roden, J., Haresign, W., Bunger, L., Dwyer, C.M. 2011. Selection of sires with good lambing and lamb vigour characteristics within three Suffolk strains. Cadair Other

Masri, A., Lambe, N.R., Macfarlane, J.M., Brotherstone, S., Haresign, W., Rius-Vilarrasa, E., Bunger, L. 2011. The effect of a loin muscling quantitative trait locus (LoinMAX TM) on carcass and VIA-based traits in crossbred lambs. 10.1017/S175173110999125X Cadair

Masri, A.Y., Lambe, N.R., Macfarlane, J.M., Brotherstone, S., Haresign, W., Bunger, L. 2011. Evaluating the effects of single copy of a mutation in the myostatin gene (c.*1232G > A) on carcass traits in crossbred lambs. Meat Science 87 (4) pp. 412-418. 10.1016/j.meatsci.2010.11.019 Cadair

Masri, A.Y., Lambe, N.R., Macfarlane, J.M., Brotherstone, S., Haresign, W., Bunger, L. 2011. Evaluating the effects of a single copy of a mutation in the myostatin gene (c.*1232G > A) on carcass traits in crossbred lambs. Meat Science 87 (4) pp. 412-418. Cadair

2010

Lambe, N.R., Haresign, W., Macfarlane, J.M., Richardson, R.I., Matika, O., Bunger, L. 2010. The effect of conditioning period on loin muscle tenderness in crossbred lambs with or without the Texel Muscling QTL (TM-QTL). Meat Science 85 (4) pp. 715-720. 10.1016/j.meatsci.2010.03.029 Cadair

Mekkawy, W., Roehe, R., Lewis, R.M., Davies, M.H., Bunger, L., Simm, G., Haresign, W. 2010. Comparison of repeatability and multiple trait threshold models for litter size in sheep using observed and simulated data in Bayesian analyses. Journal of Animal Breeding and Genetics 127 (4) pp. 261-271. 10.1111/j.1439-0388.2010.00852.x Cadair

Perry, K., Haresign, W., Wathes, D.C., Khalid, M. 2010. Hyaluronan (HA) content, the ratio of HA fragments and the expression of CD44 in the ovine cervix vary with stage of the oestrous cycle. Reproduction 140 (1) pp. 133-141. 10.1530/REP-09-0424 Cadair

Hastie, P.M., Haresign, W. 2010. Modulating peripheral gonadotrophin levels affects follicular expression of mRNAs encoding insulin-like growth factor binding proteins in sheep. Animal Reproduction Science 119 (3-4) pp. 198-204. 10.1016/j.anireprosci.2010.01.007 Cadair

Masri, A.Y., Lamb, N.R., Macfarlane, J.M., Brotherstone, S., Haresign, W., Rius-Vilarrasa, E., Bunger, L. 2010. The effects of a loin muscling quantitative trait locus (LoinMAX (TM)) on carcass and VIA-based traits in crossbred lambs. Animal 4 (3) pp. 407-416. Cadair

Rius-Vilarassa, E., Bunger, L., Brotherstone, S., Macfarlane, J.M., Lambe, N.R., Matthews, K.R., Haresign, W., Roehe, R. 2010. Genetic parameters for carcass dimensional measurements from Video Image Analysis and their association with conformation and fat class scores. Livestock Science 128 (1-3) pp. 92-100. 10.1016/j.livsci.2009.11.004 Cadair

Marquez, G.C., Haresign, W., Davies, M.H., Roehe, R., Bunger, L., Simm, G., Lewis, R.M. 2010. Effects of index selection and sire breed on crossbred lamb growth and finishing. Journal of Dairy Science 93 (Supplement 1) pp. 469-470. Cadair

Perry, K., Haresign, W., Wathes, D.C., Khalid, M. 2010. Intracervical application of hyaluronan improves cervical relaxation in the ewe. Theriogenology 74 (9) pp. 1685-1690. 10.1016/j.theriogenology.2010.07.008 Cadair

Lambe, N.R., Macfarlane, J.M., RIchardson, R..., Matika, O., Haresign, W., Bünger, L. 2010. The effect of Texel Muscling QTL (TM-QTL) on meat quality traits in crossbred lambs. Meat Science 85 (4) pp. 684-690. 10.1016/j.meatsci.2010.03.025 Cadair

2009

Rius-Vilarrasa, E., Roehe, R., Macfarlane, J.M., Lambe, N.R., Matthews, K.R., Haresign, W., Matika, O., Bunger, L. 2009. Effects of a quantitative trait locus for increased muscularity on carcass traits measured by subjective conformation and fat class scores and video image analysis in crossbred lambs. Animal 3 (11) pp. 1532-1543. 10.1017/S1751731109990413 Cadair

Mekkawy, W., Roehe, R., Lewis, R.M., Davies, M.H., Bunger, L., Simm, G., Haresign, W. 2009. Genetic relationship between longevity and objectively or subjectively assessed performance traits in sheep using linear censored models. Journal of Animal Science 87 (11) pp. 3482-3489. 10.2527/jas.2008-1398 Cadair

Rius-Vilarrasa, E., Bunger, L., Brotherstone, S., Matthews, K.M., Haresign, W., Macfarlane, J.M., Davies, M., Roehe, R. 2009. Genetic parameters for carcass composition and performance data in crossbred lambs measured by Video Image Analysis. Meat Science 81 (4) pp. 619-625. 10.1016/j.meatsci.2008.10.020 Cadair

Macfarlane, J.M., Lambe, N.R., Bishop, S.C., Matika, O., Rius-Vilarrasa, E., McLean, K.A., Haresign, W., Wolf, B.T., McLaren, R.J., Bunger, L. 2009. Effects of a Texel sheep muscling quantitative trait locus on carcass traits in crossbred lambs. Animal 3 (2) pp. 189-199. 10.1017/S175173110800356X Cadair

Gubbins, S., Cook, C.J., Hyder, K., Boulton, K., Davis, C., Thomas, E., Haresign, W., Bishop, S.C., Villaneuva, B., Eglin, R. 2009. Associations between lamb survival and prion protein genotype: analysis of data for ten sheep breeds in Great Britain. BMC Veterinary Research 5 3 10.1186/1746-6148-5-3 Cadair

Lambe, N.R., Macfarlane, J.M., Masri, A., Matika, O., Haresign, W., Bunger, L. 2009. The effect of three muscling Quantitative Trait Loci on growth patterns of cross-bred lambs. Other Cadair

Macfarlane, J.M., Lambe, N.R., Rius-Vilarrasa, E., McLean, K.A., Masri, A., Haresign, W., Matika, O., Bishop, S.C., Bunger, L. 2009. Evaluation of two muscling QTL in sheep using ultrasound (US), computer tomography (CT) and video image analysis (VIA). Book of Abstracts of the 60th Annual Meeting of the European Association for Animal Production (EAAP), Barcelona, Spain. Other Cadair

Masri, A., Macfarlane, J.M., Lambe, N.R., Haresign, W., Rius-Vilarrasa, E., Bunger, L. 2009. Comprehensive evaluation of the direct effects of LM-QTL on carcass traits in crossbred lambs. Other Cadair

Masri, A., Macfarlane, J.M., Lambe, N.R., Brotherstone, S., Haresign, W., Rius-Vilarrasa, E., Bunger, L. 2009. The effect of a loin muscling QTL (LoinMAX) in UK crossbred lambs. QMS R& D Conference, Scone, UK. Cadair

Masri, A., Macfarlane, J.M., Lambe, N., Haresign, W., Rius-Vilarrasa, E., Bunger, L. 2009. Evaluation of the direct effects of MyoMAX on carcass traits in crossbred lambs. Other Cadair

Rius-Vilarrasa, E., Bunger, L., Brotherstone, S., Matthews, K., Haresign, W., Davies, M., Roehe, R. 2009. Genetic parameters for carcass dimensional measurements from Video Image Analysis and their associations with conformation and fat class scores. Other Cadair

2008

Nieuwhof, G.J., Conington, J., Bunger, L., Haresign, W., Bishop, S.C. 2008. Genetic and phenotypic aspects of foot lesions scores in sheep of different breeds and ages. Animal 2 (9) pp. 1289-1296. Cadair

Wolf, B.T., McBride, S., Lewis, R.M., Davies, M.H., Haresign, W. 2008. Estimates of the genetic parameters and repeatability of behavioural traits of sheep in an arena test. Applied Animal Behaviour Science 112 (1-2) pp. 68-80. 10.1016/j.applanim.2007.07.011 Cadair

Wolf, B., Howells, K., Nakielny, C., Lewis, R., Davies, O., Davies, M., Haresign, W. 2008. Genetic parameters for strongyle and Nematodirus faecal egg counts in lambs and their relationships with performance traits. Livestock Science 113 (2-3) pp. 209-217. 10.1016/j.livsci.2007.03.011 Other Cadair

Hastie, P.M., Haresign, W. 2008. Modulating peripheral gonadotrophin levels affects follicular expression of mRNAs encoding insulin-like growth factors and receptors in sheep. Animal Reproduction Science 109 (1-4) pp. 110-123. 10.1016/j.anireprosci.2007.10.006 Cadair

Nieuwhof, G.J., Conington, J., Bunger, L., Haresign, W., Bishop, S.C. 2008. Genetic and phenotypic aspects of foot lesion scores in sheep of different breeds and ages. Animal 2 (9) pp. 1289-1296. 10.1017/S1751731108002577 Cadair

2007

Husain, S., Wolf, B.T., Haresign, W. 2007. Genetic parameters of lamb weights and ultrasonic muscle and fat depths in Beulah Specklefaced sheep. Small Ruminant Research 70 (2-3) pp. 116-123. 10.1016/j.smallrumres.2006.01.011 Cadair

Rose, M.T., Wolf, B.T., Haresign, W. 2007. Effect of the level of iodine in the diet of pregnant ewes on the concentration of immunoglobulin G in the plasma of neonatal lambs following the consumption of colostrum. British Journal of Nutrition 97 (2) pp. 315-320. 10.1017/S0007114507337306 Cadair

2006

Hastie, P.M., Haresign, W. 2006. A role for LH in the regulation of expression of mRNAs encoding components of the insulin-like growth factor (IGF) system in the ovine corpus luteum. Animal Reproduction Science 96 (1-2) pp. 196-209. 10.1016/j.anireprosci.2005.12.009 Cadair

van Heelsum, A.M., Lewis, R.M., Davies, M.H., Haresign, W. 2006. Genetic relationships among objectively and subjectively assessed traits measured on crossbred (Mule) lambs. Animal Science 82 (2) pp. 141-149. 10.1079/ASC200523 Cadair

Hastie, P.M., Haresign, W. 2006. Expression of mRNAs encoding insulin-like growth factor (IGF) ligands, IGF receptors and IGF binding proteins during follicular growth and atresia in the ovine ovary throughout the oestrous cycle. Animal Reproduction Science 92 (3-4) pp. 284-299. 10.1016/j.anireprosci.2005.05.022 Cadair

Roden, J.A., Nieuwhof, G.J., Bishop, S.C., Jones, D.A., Haresign, W., Gubbins, S. 2006. Breeding programmes for TSE resistance in British sheep - I. Assessing the impact on prion protein (PrP) genotype frequencies. Preventive Veterinary Medicine 73 (1) pp. 1-16. 10.1016/j.prevetmed.2005.08.002 Cadair

Lewis, R.M., van Heelsum, A.M., Haresign, W., Davies, M.H., Roehe, R., Bunger, L., Simm, G. 2006. Role of sire referencing schemes in terminal sire sheep to improve carcass quality in crossbred lambs. Journal of Animal Science 84 (2) pp. 445-445. Cadair

2005

Speijers, M.H.M., Fraser, M.D., Haresign, W., Theobald, V.J., Moorby, J.M. 2005. Effects of ensiled forage legumes on performance of twin-bearing ewes and their progeny. Animal Science 81 (2) pp. 271-282. 10.1079/ASC50510271 Cadair Other

Speijers, M.H.M., Fraser, M.D., Theobald, V.J., Haresign, W. 2005. Effects of ensiled forage legumes on performance of store finishing lambs. Animal Feed Science and Technology 120 (3-4) pp. 203-216. 10.1016/j.anifeedsci.2005.02.027 Cadair

2004

Moorby, J.M., Fraser, M.D., Theobald, V.J., Wood, J.D., Haresign, W. 2004. The effect of red clover formononetin content on live weight gain, carcass characteristics and muscle equol content of finishing lambs. Animal Science 79 (2) pp. 303-313. Cadair Other

Hastie, P.M., Onagbesan, O.M., Haresign, W. 2004. Co-expression of messenger ribonucleic acids encoding IGF-I, IGF-II, type I and II IGF receptors and IGF-binding proteins (IGFBP-1 to-6) during follicular development in the ovary of seasonally anoestrous ewes. Animal Reproduction Science 84 (1-2) pp. 93-105. 10.1016/j.anireprosci.2003.10.012 Cadair

Speijers, M.H.M., Fraser, M.D., Theobald, V.J., Haresign, W. 2004. The effects of grazing forage legumes on the performance of finishing lambs. Journal of Agricultural Science 142 (4) pp. 483-493. 10.1017/S0021859604004496 Cadair

McConochie, H., Rose, M., Haresign, W., Davies, B. 2004. Mammary specific function of a bovine mammary epithelial cell clone cultured on collagen I coated inserts. Journal of Animal and Feed Sciences 13 (Supplement 1) 10th International Symposium on Ruminant Pysiology. pp. 523-526. Cadair

2003

Roden, J.A., Merrell, B.G., Murray, W.A., Haresign, W. 2003. Genetic analysis of live weight and ultrasonic fat and muscle traits in a hill sheep flock undergoing breed improvement utilizing an embryo transfer programme. Animal Science 76 (3) pp. 367-373. Cadair Other

Bari, F., Khalid, M., Haresign, W., Murray, A., Merrell, B. 2003. Factors affecting the survival of sheep embryos after transfer within a MOET program. Theriogenology 59 (5-6) pp. 1265-1275. 10.1016/S0093-691X(02)01162-7 Other Cadair

van Heelsum, A.M., Lewis, R.M., Davies, M.H., Haresign, W. 2003. Growth and carcass characteristics in wether lambs of a crossbred dam line. Animal Science 76 (1) pp. 43-53. Cadair

Fraser, M.D., Haresign, W., Speijers, M.H.M., Theobald, V.J., Roberts, J.E., Fychan, A.R. 2003. Ensiled legumes as a feed for store lambs. Cadair Other

2002

Willlams, R.J., Marlin, D.J., Smith, N., Harris, R.C., Haresign, W., Davies-Morel, M.C.G. 2002. Effects of cool and hot humid environmental conditions on neuroendocrine responses of horses to treadmill exercise. Veterinary Journal 164 (1) pp. 54-63. 10.1053/tvjl.2002.0721 Cadair

Petit, H.V., Dewhurst, R.J., Scollan, N.D., Proulx, J.G., Khalid, M., Haresign, W., Twagiramungu, H., Mann, G.E. 2002. Milk production and composition, ovarian function, and prostaglandin secretion of dairy cows fed omega-3 fats. Journal of Dairy Science 85 (4) pp. 889-899. Cadair Other

2001

Mann, G.E., Haresign, W. 2001. Effect of oestradiol treatment during GnRH-induced ovulation on subsequent PGF(2 alpha) release and luteal life span in anoestrous ewes. Animal Reproduction Science 67 (3-4) pp. 245-252. 10.1016/S0378-4320(01)00123-3 Cadair

Bari, F., Khalid, M., Wolf, B.T., Haresign, W., Murray, A., Merrell, B. 2001. The repeatability of superovulatory response and embryo recovery in sheep. Theriogenology 56 (1) pp. 147-155. 10.1016/S0093-691X(01)00550-7 Cadair

Petit, H.V., Dewhurst, R.J., Proulx, J.G., Khalid, M., Haresign, W., Twagiramungu, H. 2001. Milk production, milk composition and reproductive function of dairy cows fed different fats. Canadian Journal of Animal Science 81 (2) pp. 263-271. 10.4141/A00-096 Cadair Other

van Heelsum, A.M., Lewis, R.M., Haresign, W., Williams, S.P., Davies, M.H. 2001. Non-normality in carcass quality measurements and effects on the genetic evaluation of sheep. Livestock Production Science 69 (2) pp. 113-127. 10.1016/S0301-6226(00)00261-X Cadair

2000

Joyce, I.M., Khalid, M., Haresign, W. 2000. The effect of recombinant GH treatment on ovarian follicle growth and atresia in sheep. Theriogenology 54 (2) pp. 327-338. 10.1016/S0093-691X(00)00352-6 Cadair