Photograph of Dr Sharon Huws.Dr Sharon Huws

Coleg Cymraeg Cenedlaethol Lecturer in Animal Science
PhD

Contact

Email: hnh@aber.ac.uk
Office: Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Edward Llwyd Building, Penglais Campus, Aberystwyth, Ceredigion, UK, SY23 3DA.
Phone: +44 1970 823202

Responsibilities

Sharon is a Lecturer in Animal Science with the remit of teaching undergraduates and postgraduates (75% in Welsh and 25% in English; funded by the Coleg Cymraeg Cenedlaethol).  As well as a teaching role she leads a research group focussed on understanding the functionality of the rumen gut microbiome with the ultimate goal being to increase ruminant nutrient use efficiency and product quality. Alongside the rumen-focussed research her group are involved in investigating the lung microbiome in disease status, and prospecting metagenomic libraries (rumen libraries and those made from other bacterial ecosystems) for enzymes important to the biotechnology industry. Genomics, metagenomics and metatranscriptomics alongside bioinformatics are central techniques used by her group in order to deliver a fundamental understanding of these ecosystems. Sharon also works with many industrial partners to ensure application of some of the research outcomes. She also represents IBERS as part of the rumen microbial networks consortia led by AgResearch, New Zealand.

Teaching Areas

Research

Research Team and their Activities

  • Dr Ana Schogor (Post-doctoral researcher funded by Brazilian Science without borders) – Investigations into the metabolism of secoisolariciresinol diglucosidase by the rumen microbiota.
  • Ms Hannah Vallin (Research Assistant funded by a Welsh government large application development project funding linked to many industrial partners) – Project title ‘Improving Milk Quality using green odour volatile compounds’..
  • Mr Rodolpho Prado (PhD student funded by Brazilian Science without borders; main supervisor Dr Sharon Huws and second supervisor Dr David Whitworth) –  Project Title ‘Membrane vesicles: An overlooked critical component of rumen plant-microbe biofilms’.
  • Ms Sarah Morgan (KESS funded PhD student; main supervisor Prof Nigel Scollan and second supervisor Dr Sharon Huws) – Project Title ‘Enhancing the nutritional properties, in particular fatty acid composition, of beef & forage’.

Current funding

  • April, 2014 for 6 months (£60,000) – A4B funding to test ‘green odour’ chemicals in vivo.
  • March, 2014 for a period of 3 years (£30,000) – Brazil Special Visiting Researcher Award.
  • March, 2014 for a period of 4 years (£42,000) – BBSRC Brazil Partnering Award in conjunction with the University of Viçosa to further develop linkages with themselves and IBERS.
  • January, 2014 for 6 months (£20,000) – BBSRC Pathfinder Award.  Project investigates the use of our metagenomically discovered rumen lipases for efficient bioplastic production.
  • October, 2013 for 6 months (£20,000) – BBSRC SPARK Award.  Project investigates the use of our metagenomically discovered rumen lipases for efficient biodiesel production.
  • September, 2013 for a period of 3 years (£200,000) - BBSRC India Link. This project was obtained as part of an international team with IBERS contribution led by Dr Jessica Adams.  The project encompasses biorefining of algae with a strong emphasis on ‘omic based enzyme prospecting.
  • September, 2013 for a period of one year – KESS MPhil studentship funding obtained.
  • September, 2013 for 3 years – Brazil Science Without Borders PhD studentship obtained.
  • January, 2013 for 1 year – Brazil Science Without Border Postdoctoral Award obtained for Dr Ana Schogor to join the group.

Staff Links

Publications

2016

Cameron, S., E. Lewis, K., Huws, S., Lin, W., Hegarty, M., D. Lewis, P., Mur, L., Pachebat, J.A. 2016. Metagenomic Sequencing of the Chronic Obstructive Pulmonary Disease Upper Bronchial Tract Microbiome Reveals Functional Changes Associated with Disease Severity. PLoS One 11 (2) 0149095 10.1371/journal.pone.0149095

Huws, S., Edwards, J.E., Creevey, C., Rees Stevens, P., Lin, W., Girdwood, S., Pachebat, J., Kingston-Smith, A. 2016. Temporal dynamics of the metabolically active rumen bacteria colonising fresh perennial ryegrass. FEMS Microbiology Ecology 92 (1) 10.1093/femsec/fiv137

2015

Huws, S., Kim, E.J., Cameron, S.J., Girdwood, S.E., Davies, L.J., Tweed, J., Vallin, H.E., Scollan, N. 2015. Characterization of the rumen lipidome and microbiome of steers fed a diet supplemented with flax and echium oil. Microbial Biotechnology 8 (2) pp. 331-341. 10.1111/1751-7915.12164 Other

Privé, F., Newbold, C.J., Kaderbhai, N.N., Girdwood, S.G., Golyshina, O.V., Golyshin, P.N., Scollan, N.D., Huws, S.A. 2015. Isolation and characterization of novel lipases/esterases from a bovine rumen metagenome. Applied Microbiology and Biotechnology 99 (13) pp. 5475-5485. 10.1007/s00253-014-6355-6

Cameron, S.J.S., Huws, S., Hegarty, M.J., Smith, D.P.M., Mur, L.A.J. 2015. The human salivary microbiome exhibits temporal stability in bacterial diversity. FEMS Microbiology Ecology 91 (9) fiv091 10.1093/femsec/fiv091

2014

A Huws, S., Mayorga, O.L., Theodorou, M.K., Kim, E.J., Cookson, A., Newbold, J., Kingston-Smith, A.H. 2014. Differential Colonization of Plant Parts by the Rumen Microbiota is likely to be due to Different Forage Chemistries. Journal of Microbial and Biochemical Technology 6 (2) pp. 80-86. 10.4172/1948-5948.1000126 Other

Dudek, M., Adams, J., Swain, M., Hegarty, M., Huws, S., Gallagher, J. 2014. Metaphylogenomic and Potential Functionality of the Limpet Patella pellucida’s Gastrointestinal Tract Microbiome. International Journal of Molecular Sciences 15 (10) pp. 18819-18839. 10.3390/ijms151018819

Schogor, A.L.B., Huws, S.A., Santos, G.T.D., Scollan, N.D., Hauck, B.D., Winters, A.L., Kim, E.J., Petit, H.V., 2014. Ruminal Prevotella spp. May Play an Important Role in the Conversion of Plant Lignans into Human Health Beneficial Antioxidants. PLoS One 9 (4) e87949 10.1371/journal.pone.0087949 Other

2013

Huws, S.A., Scott, M.B., Tweed, J.K.S., Lee, M.R.F. 2013. Fatty acid oxidation products (‘green odour’) released from perennial ryegrass following biotic and abiotic stress, potentially have antimicrobial properties against the rumen microbiota resulting in decreased biohydrogenation. Journal of Applied Microbiology 115 (5) pp. 1081-1090. 10.1111/jam.12314

Privé, F., Kaderbhai, N.N., Girdwood, S., Worgan, H.J., Pinloche, E., Scollan, N.D., Huws, S.A., Newbold, C.J. 2013. Identification and Characterization of Three Novel Lipases Belonging to Families II and V from Anaerovibrio lipolyticus 5ST. PLoS One 8 (8) e69076 10.1371/journal.pone.0069076

Huws, S.A., Griffith, G.W., Edwards, J.E., Williams, H.W., James, W.P., Owen, I.G., Kingston-Smith, A.H. 2013. Sicrhau argaeledd cynnyrch cil gnowyr o'r ansawdd orau mewn modd effethlon. Gwerddon 13 pp. 10-28.

Huws, S.A., Mayorga, O.L., Theodorou, M.K., Onime, L.A., Kim, E.J., Cookson, A.H., Newbold, C.J., Kingston-Smith, A.H. 2013. Successional colonization of perennial ryegrass by rumen bacteria. Letters in Applied Microbiology 56 (3) pp. 186-196. 10.1111/lam.12033

2012

Huws, S.A., Chiariotti, A., Sarubbi, F., Carfì, F., Pace, V. 2012. Effects of feeding Mediterranean buffalo sorghum silage versus maize silage on the rumen microbiota and milk fatty acid content. Journal of General and Applied Microbiology 58 (2) pp. 107-112. 10.2323/jgam.58.107

Alcaide, M., Messina, E., Richter, M., Bargiela, R., Peplies, J., Huws, S.A., Newbold, C.J., Golyshin, P.N., Simón, M.A., López, G., Yakimov, M.M., Ferrer, M. 2012. Gene sets for utilization of primary and secondary nutrition supplies in the distal gut of endangered iberian lynx. PLoS One 7 (12) e51521 10.1371/journal.pone.0051521

Del Pozo, M.V., Fernández-Arrojo, L., Gil-Martínez, J., Montesinos, A., Chernikova, T.N., Nechitaylo, T.Y., Waliszek, A., Tortajada, M., Rojas, A., Huws, S.A., Golyshina, O.V., Newbold, C.J., Polaina, J., Ferrer, M., Golyshin, P.N. 2012. Microbial β-glucosidases from cow rumen metagenome enhance the saccharification of lignocellulose in combination with commercial cellulase cocktail. Biotechnology for Biofuels 5 (1) 73 10.1186/1754-6834-5-73

Morgan, S., Huws, S.A., Scollan, N.D. 2012. Progress in forage-based strategies to improve the fatty acid composition of beef. Proceedings of 24th General Meeting of the European Grassland Federation, Lublin, Poland, 03/06/2012 - 07/06/2012.

Huws, S.A., Lee, M.R.F., Kingston-Smith, A.H., Kim, E.J., Scott, M.B., Tweed, J., Scollan, N.D. 2012. Ruminal protozoal contribution to the duodenal flow of fatty acids following feeding of steers on forages differeing in chloroplast content. British Journal of Nutrition 108 (12) pp. 2207-2214. 10.1017/S0007114512000335

2011

Huws, S.A., Kim, E.J., Lee, M.R., Scott, M.B., Tweed, J.K., Pinloche, E., Wallace, R.J., Scollan, N.D. 2011. As yet uncultured bacteria phylogenetically classified as Prevotella, Lachnospiraceae incertae sedis and unclassified Bacteroidales, Clostridiales and Ruminococcaceae may play a predominant role in ruminal biohydrogenation. Environmental Microbiology 13 (6) pp. 1500-1512. 10.1111/j.1462-2920.2011.02452.x Cadair

Huws, S.A., Kingston-Smith, A.H., Kim, E.J., Lee, M.R.F., Scott, M.B.S., Scollan, N.D. 2011. Contribution of ruminal protozoa to the duodenal flow of polyunsaturated fatty acids following feeding on low and high chloroplast-containing diets. ASF/AVTR/BSAS/WPSA Annual Conference, 'Food Security - Challenges and Opportunities for Animal Science, Nottingham University, , 04/04/2011 - 05/04/2011.

2010

Huws, S.A., Kim, E.J., Lee, M.R.F., Scott, M.B., Tweed, J.K.S., Pinloche, E., Wallace, R.J., Scollan, N.D. 2010. As yet uncultured bacteria may play a predominant role in ruminal biohydrogenation. ProSafeBeef Annual General Meeting - EU Framework 6, Aberystwyth, United Kingdom of Great Britain and Northern Ireland, 05/10/2010 - 07/10/2010. pp. p 52.

Edwards, J.E., Yeoman, C.J., Huws, S.A., Kingston-Smith, A.H., Mackie, R.I. 2010. Biofilm formation and growth dynamics of Prevotella ruminicola during the colonisation of fresh perennial ryegrass. Gut Microbiology: New insights into gut microbial ecosystems, 7th Joint Symposium Rowett-INRA Meeting, Aberdeen Exhibition and Conference Centre, , 23/06/2010 - 25/06/2010.

Huws, S.A., Kingston-Smith, A.H., Kim, E.J., Lee, M.R.F., Scott, M.B., Tweed, J.K.S., Scollan, N.D. 2010. Contribution of ruminal protozoa to the duodenal flow of polyunsaturated fatty acids as a consequence of intracellular chloroplasts.

Huws, S.A., Kingston-Smith, A.H., Kim, E.J., Lee, M.R.F., Scott, M.B., Tweed, J.K.S., Scollan, N.D. 2010. Contribution of ruminal protozoa to the duodenal flow of polyunsaturated fatty acids following feeding on low and high chloroplasts. ProSafeBeef Annual General Meeting - EU Framework 6, Aberystwyth, United Kingdom of Great Britain and Northern Ireland, 05/10/2010 - 07/10/2010. pp. p 53.

Huws, S.A., Chiariotti, A. 2010. Effect of diets on bacterial population diversity in buffalo rumen as revealed by DGGE and T-RFLP analysis. Gut Microbiology: New insights into gut microbial ecosystems, 7th Joint Symposium Rowett-INRA Meeting, Aberdeen Exhibition and Conference Centre, , 23/06/2010 - 25/06/2010.

Huws, S.A., Scott, M.B., Tweed, J.K.S., Lee, M.R.F. 2010. Effects of fatty acid oxidation products ('green odour') on rumen bacterial populations and lipid metabolism in vitro. ProSafeBeef Annual General Meeting - EU Framework 6, Aberystwyth, United Kingdom of Great Britain and Northern Ireland, 05/10/2010 - 07/10/2010. pp. 50.

Huws, S.A., Scott, M.B., Tweed, J.K./.S., Lee, M.R.F. 2010. Effects of fatty acid oxidation products (‘green odour’) on rumen bacterial populations and lipid metabolism in vitro.

Huws, S.A., Lee, M.R.F., Muetzel, S.M., Scott, M.B., Wallace, R.J., Scollan, N.D. 2010. Forage type and fish oil cause shifts in rumen bacterial diversity. FEMS Microbiology Ecology 73 (2) pp. 396-407. 10.1111/j.1574-6941.2010.00892.x Cadair

Baré, J., Sabbe, K., Huws, S.A., Vercauteren, D., Braeckmans, K., van Gremberghe, I., Favoreel, H., Houf, K. 2010. Influence of temperature, oxygen, bacterial origin and invasiveness on the association of Campylobacter jejuni with Acanthamoeba castellanii. FEMS Microbiology Ecology 74 (2) pp. 371-381. 10.1111/j.1574-6941.2010.00955.x Cadair

Privé, F., Newbold, C.J., Scollan, N.D., Golyshin, P.N., Huws, S.A. 2010. New insights on ruminal lipolysis using metagenomics. Advancing Beef Safety and Quality through Research and Innovation. An International Conference organised by ProSafeBeef, United Kingdom of Great Britain and Northern Ireland, 06/10/2010 - 07/10/2010.

Kingston-Smith, A.H., Edwards, J.E., Huws, S.A., Kim, E.J., Abberton, M.T. 2010. Plant-based strategies towards minimising livestock's long shadow. Proceedings of the Nutrition Society 69 (4) The Winter Meeting of the Nutrition Society, Reading, United Kingdom of Great Britain and Northern Ireland, 15/12/2009 - 15/12/2009. pp. 613-620. 10.1017/S0029665110001953 Cadair

Huws, S.A., Lee, M.R.F., Tweed, J.K.S., Scott, M.B., Scollan, N.D. 2010. Saponins extracted from Yucca shidigera cause shifts in the rumen microbiota resulting in decreased lipolysis and biohydrogenation.

Huws, S.A., Lee, M.R.F., Tweed, J.K.S., Scott, M.B., Scollan, N.D. 2010. Yucca shidigera extracted saponin cause shifts in the rumen microbiota alongside decreased lipolysis and biohydrogenation. ProSafeBeef Annual General Meeting - EU Framework 6, Aberystwyth, United Kingdom of Great Britain and Northern Ireland, 05/10/2010 - 07/10/2010. pp. p 51.

2009

Kim, E.J., Huws, S.A., Lee, M.R.F., Scollan, N.D. 2009. Dietary transformation of lipid in the rumen microbial ecosystem. Asian-Australasian Journal of Animal Sciences. 5th International Symposium on Recent Advances in Animal Nutrition, Hanoi, Viet Nam, 22/09/2008 - 25/09/2008. Asian-Australasian Association of Animal Production Societies pp. 1341-1350. Cadair Other

Huws, S.A., Kim, E.J., Kingston-Smith, A.H., Lee, M.R., Muetzel, S.M., Cookson, A.R., Newbold, J., Wallace, R.J., Scollan, N.D. 2009. Rumen protozoa are rich in polyunsaturated fatty acids due to the ingestion of chloroplasts. FEMS Microbiology Ecology 69 (3) pp. 461-471. 10.1111/j.1574-6941.2009.00717.x Cadair

Huws, S.A., Kim, E.J., lee, M.R.F., Pinloche, E., Wallace, R.I., Scollan, N.D. 2009. The effects of incremental fish oil supplementation on bacterial populations in the rumen. In Y. Chilliard, F. Glasser, Y. Faulconnier, F. Bocquier, I. Veissie, M. Doreau (eds), Ruminant Physiology: Digestion, Metabolism and Effects of Nutrition on Reproduction and Welfare . XIth International Symposium on Ruminant Physiology (ISRP 2009), Clermont-Ferrand, France, 14/09/2009 - 16/09/2009. Wageningen Academic Publishers pp. 82-83. Cadair Other

2008

Edwards, J.E., Huws, S.A., Kim, E.J., Lee, M.R.F., Kingston-Smith, A.H., Scollan, N.D. 2008. Advances in microbial ecosystem concepts and their consequences for ruminant agriculture. animal 2 (5) pp. 653-660. 10.1017/S1751731108002164 Cadair

Edwards, J.E., Huws, S.A., Kim, E.J., Kingston-Smith, A.H. 2008. Characterization of the dynamics of initial bacterial colonization of nonconserved forage in the bovine rumen. FEMS Microbiology Ecology 63 (1) pp. 141-142. 10.1111/j.1574-6941.2007.00413.x

Mayorga, O.L., Huws, S.A., Kim, E.J., Kingston-Smith, A.H., Cookson, A.H., Newbold, C.J., Theodorou, M.K. 2008. Differential colonisation of abaxial and adaxial surfaces of fresh perennial ryegrass leaves by rumen bacteria. Abstract, INRA-RRI 2008, Clermont Ferrand, France, , 18/06/2008 - 20/06/2008.

Edwards, J.E., Kingston-Smith, A.H., Jimenez, H.R., Huws, S.A., Skot, K.P., Griffith, G.W., McEwan, N.R., Theodorou, M.K. 2008. Dynamics of initial colonisation of non-conserved perennial ryegrass by anaerobic fungi in the bovine rumen. FEMS Microbiology Ecology 66 (3) pp. 537-545. 10.1111/j.1574-6941.2008.00563.x Cadair Other

Lee, M.R.F., Shingfield, K.J., Tweed, J.K.S., Toivonen, V., Huws, S.A., Scollan, N.D. 2008. Effect of fish oil on ruminal biohydrogenation of C18 unsaturated fatty acids in steers fed grass or red clover silages. animal 2 (12) pp. 1859-1869. 10.1017/S1751731108002899 Cadair

Kingston-Smith, A.H., Huws, S.A., Edwards, J.E., 2008. Exploiting the dynamic nature of the plant-microbe interactions in the rumen. IBERS Knowledge-based Innovations pp. 13-16. Other

Kim, E.J., Huws, S.A., Lee, M.R., Wood, J.D., Muetzel, S.M., Wallace, R.J., Scollan, N.D. 2008. Fish Oil Increases the Duodenal Flow of Long Chain Polyunsaturated Fatty Acids and trans-11 18:1 and Decreases 18:0 in Steers via Changes in the Rumen Bacterial Community. Journal of Nutrition 138 (5) pp. 889-896. Cadair Other Other

Mayorga, O.L., Huws, S.A., Kim, E.J., Kingston-Smith, A.H., Newbold, C.J., Theodorou, M.K. 2008. In vitro production and composition of extracellular polymeric substances formed by ruminal bacteria on perennial ryegrass. Society for General Microbiology general meeting, Dublin, Ireland, 8-11 September, , 01/01/2008 - 01/01/2008. pp. p70. Other

Huws, S.A., Morley, R.J., Jones, M.V., Brown, M.R.W., Smith, A.W. 2008. Interactions of some common pathogenic bacteria with Acanthamoeba polyphaga. FEMS Microbiology Letters 282 (2) pp. 258-265. 10.1111/j.1574-6968.2008.01123.x Other Cadair Other

Mayorga, O.L., Huws, S.A., Kim, E.J., Kingston-Smith, A.H., Cookson, A.H., Newbold, C.J., Theodorou, M.K. 2008. Temporal and spatial colonisation of rumen protozoa on fresh perennial ryegrass. Abstract, INRA-RRI 2008, Clermont Ferrand, France, , 18/06/2008 - 20/06/2008.

Huws, S.A., Wallace, R.J., Scollan, N.D., Lee, M.R.F., Pinloche, E., Kim, E.J. 2008. Understanding the role of bacteria in the biohydrogenation pathways within the rumen. 6th joint INRA­RRI Symposium. GUT MICROBIOME: Functionality, interaction with the host and impact on the environment. Clermont­Ferrand, France. 18 ­ 20 June 2008. GUT MICROBIOME: Functionality, interaction with the host and impact on the environment, Clermont-Ferrand, France, 18/06/2008 - 20/06/2008. pp. 41-42. Cadair

2007

Edwards, J.E., Huws, S.A., Kim, E.J., Kingston-Smith, A.H. 2007. Characterization of the dynamics of initial bacterial colonization of nonconserved forage in the bovine rumen. FEMS Microbiology Ecology 62 (3) pp. 323-335. 10.1111/j.1574-6941.2007.00392.x Cadair

Lee, M.R., Huws, S., Scollan, N., Dewhurst, R.J. 2007. Effects of fatty acid oxidation products (‘Green odour’) on rumen bacterial populations and lipid metabolism in vitro. Journal of Dairy Science 90 (8) pp. 3874-3882. 10.3168/jds.2007-0191 Other

Ledder, R.G., Gilbert, P., Huws, S., Aarons, L., Ashley, M.P., Hull, P.S., McBain, A.J. 2007. Molecular analysis of the subgingival microbiota in health and disease. Applied and Environmental Microbiology 73 (2) pp. 516-523. 10.1128/AEM.01419-06 Other

Huws, S.A., Edwards, J.E., Kim, E.J., Scollan, N.D. 2007. Specificity and sensitivity of eubacterial primers utilized for molecular profiling of bacteria within complex microbial ecosystems. Journal of Microbiological Methods 70 (3) pp. 565-569. 10.1016/j.mimet.2007.06.013 Cadair

2006

Huws, S.A., Smith, A.W., Enright, M.C., Wood, P.J., Brown, M.R.W. 2006. Amoebae promote persistence of epidemic strains of MRSA. Environmental Microbiology 8 (6) pp. 1130-1133. 10.1111/j.1462-2920.2006.00991.x Cadair

Huws, S.A., Lee, M.R.F., Muetzel, S.M., Wallace, J.D., Scollan, N.D. 2006. Effect of forage type and level of fish oil inclusion on bacterial diversity in the rumen. Gut Microbiology: Research to Improve Health, Immune Response and Nutrition, United Kingdom of Great Britain and Northern Ireland, 21/06/2006 - 23/06/2006. pp. S99. Cadair

Huws, S.A., Kim, E.J., Lee, M.R.F., Kingston-Smith, A.H., Scollan, N.D. 2006. Fatty acid composition of rumen protozoa: a link with chloroplast ingestion? Gut Microbiology: Research to Improve Health, Immune Response and Nutrition, United Kingdom of Great Britain and Northern Ireland, 21/06/2006 - 23/06/2006. pp. S98-S99. Cadair

2005

Scollan, N., Huws, S. 2005. Enrichment of ruminant products with beneficial fatty acids. RAAN Conference Proceedings. pp. 21-31. Other

Huws, S.A., McBain, A.J., Gilbert, P. 2005. Protozoan grazing and its impact upon population dynamics in biofilm communities. Journal of Applied Microbiology 98 (1) pp. 238-244. 10.1111/j.1365-2672.2004.02449.x

2003

McBain, A.J., Bartolo, R.G., Catrenich, C.E., Charbonneau, D., Ledder, R.G., Rickard, A.H., Huws, S., Gilbert, P. 2003. Microbial Characterization of Biofilms in Domestic Drains and the Establishment of Stable Biofilm Microcosms. Applied and Environmental Microbiology 69 (1) pp. 177-185. 10.1128/AEM.69.1.177-185.2003 Other