Jackson, Dr Joseph A.

Lecturer in Zoology
Photograph of Jackson, Dr Joseph A..

Contact

Email: jaj11@aber.ac.uk
Office: Z1.05 Edward Llwyd Building, Penglais Campus
Phone: +44 (0) 1970622324

Teaching Areas

2010-11

Population and Community Ecology - BS32720
Advanced Vertebrate Zoology - BS23820
Gametes, Cells and Animal Development - BS22320

Research

General interests:  The ecology and evolution of host-parasite interactions. Particularly focussing on the role of the immune system.

Main current focus: The application of modern immunological profiling to wild vertebrates (e.g., Jackson et al. 2009, 2011) to study basic questions in biology. For example, aberrant inflammatory responses are an increasing source of ill health in modern humans exposed to highly artificial environments. A particular aim is therefore to develop wild mammals as a natural model to help identify the unknown causes of this phenomenon (Friberg et al. 2010).

Biography

After graduating with a 1st class B. Sc. (Hons) in Marine Biology from the University of Wales (Swansea) in 1988 I then completed a Ph. D. in Parasitology at Queen Mary, University of London (1993).  I arrived at IBERS (2010) after previous posts at The University of Bristol (1996-2002), The University of Nottingham (2003-2008) and The University of Liverpool (2008-2010).

Staff Links

Aquatic, Behavioural & Evolutionary Biology Research Group (ABEB)

Staff Publications

Jackson, J.A., Begon, M., Birtles, R., Paterson, S., Friberg, I.M., Hall, A., Lowe, A., Ralli, C., Turner, A., Zawadzka, M., Bradley, J.E. 2011.  The analysis of immunological profiles in wild animals: a case study on immunodynamics in the field vole, Microtus agrestis. Molecular Ecology, in press.

Friberg, I.M., Bradley, J.E., Jackson, J.A. 2010. Macroparasites, innate immunity and immunoregulation: developing natural models. Trends in Parasitology, in press.

Jackson, J.A, Friberg, I.M., Bolch, L., Lowe, A., Ralli, C., Harris, P.D., Behnke, J.M. Bradley J.E. 2009. Immunomodulatory parasites drive innate immune activation levels in wild mammals. BMC Biology, 7:16.

Jackson, J.A., Friberg, I.M., Little, S. & Bradley J.E. 2009. Immunity against helminths and immunological phenomena in modern human populations: coevolutionary legacies? Immunology 126, 18-27.

Turner, J.D., Jackson, J.A., Faulkner, H., Behnke, J., Else, K.J., Kamgno, J., Boussinesq, M. & Bradley, J.E. 2008. Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness. Journal of Infectious Diseases, 197, 1204-1212.

Bradley, J.E. & Jackson, J.A. 2008. Measuring immune system variation to help understand host-pathogen community dynamics. Parasitology 135, S807-S823.

Jackson, J.A., Pleass, R.J., Cable, J., Bradley, J.E., Tinsley, R.C. 2006a. Heterogenous interspecific interactions in a host-parasite system. International Journal for Parasitology, 36, 1341-1349.

Jackson, J.A., Turner, J.D., Kamal, M., Wright, V., Bickle, Q., Else, K.J., Ramsan, M., Bradley, J.E. 2006b. Gastrointestinal nematode infection is associated with variation in innate immune responsiveness. Microbes and Infection 8, 487-492.

Jackson, J.A. & Tinsley, R.C. 2005. Geographic and within-population structure of variable resistance to parasite species and strains in a vertebrate host. International Journal for Parasitology 35, 29-37.

Jackson, J.A., Turner, J.D., Rentoul, L., Faulkner, F., Behnke, J.M. Hoyle, M., Grencis, R.K., Else, K.J. Kamgno, J., Boussinesq, M. & Bradley, J.E. 2004a. T-helper cell type 2 responsiveness predicts future susceptibility to gastrointestinal nematodes in humans. Journal of Infectious Diseases 190, 1804-1811.

Jackson, J.A., Turner, J.D., Rentoul, L., Faulkner, H., Behnke, J.M., Hoyle, M., Grencis, R.K., Else, K.J., Kamgno, J., Bradley, J.E. & Boussinesq, M. 2004b. Cytokine response profiles predict species-specific infection patterns in human GI nematodes. International Journal for Parasitology 34, 1237-1244.

Jackson, J.A. & Tinsley, R.C. 2003a Postlarval Protopolystoma spp. kidney infections in incompatible Xenopus spp. induce weak resistance to heterospecifics. Parasitology Research 90,429-34.

Jackson, J.A. & Tinsley, R.C. 2003b Parasite infectivity to hybridising host species: a link between hybrid resistance and allopolyploid speciation? International Journal for Parasitology 33, 137-44

Jackson J.A. & Tinsley, R.C. 2002 Effects of environmental temperature on the susceptibility of Xenopus laevis and X. wittei (Anura) to Protopolystoma xenopodis (Monogenea). Parasitology Research 88, 632-638.

Jackson, J.A. & Tinsley, R.C. 2001 Protopolystoma xenopodis (Monogenea) primary and secondary infections in Xenopus laevis. Parasitology 123, 455-463.