|Module Title||INTRODUCTORY BIOCHEMISTRY|
|Co-ordinator||Dr David Hopper|
|Other staff||Dr David Lamb|
|Pre-Requisite||GCSE Science or its equivalent.|
|Course delivery||Lecture||20 Hours|
|Practical||12 Hours (4 x 3 hours)|
|Assessment||Continuous assessment||Continuous assessment of practical work.||30%|
|Exam||2 Hours written semester examination.||70%|
|Resit assessment||2 Hours One 2 hour written examination; re-submission of failed course work.||100%|
Monosaccharides (simple sugars) as the building units of all complex carbohydrates will be described together with their bonding in di- and polysaccharides and the relationship of the structures of polysaccharides to their functions. The function of polysaccharides as storage and structural components of animal, plant and bacterial cells will be covered.
Amino acids as simple organic molecules and their essential properties will be described. Their linkage by peptide bonding and importance in protein composition, will be dealt with, including examples of proteins as structural components and as enzymes.
Saponifiable and unsaponifiable lipids, and structural and dietary aspects of plant and animal fatty acids will be covered and will include the nature and occurrence of neutral fats and oils, waxes, phospholipids and sphingolipids. The role of phospholipids as the basis of lipid bilayer membranes, with unsaponifiable lipid (terpenoid) and lipophilic protein inclusions will be described.
The section on nucleotides will deal with their structure and chemistry and their role in the structure of nucleic acids, including the nature of hydrogen bonding and its importance in the complementary base-pairing in DNA.
Four practical classes will introduce laboratory methods for investigating the properties of biological chemicals and will deal with isolation and some charaterisation of DNA and also the properties of enzymes. The experiments with DNA will include some spectrophotometric analysis and one session will be devoted to calculations based on spectrophotometric problmes to aid the understanding of this technique.