Rule 30: (7, lift 20.9) amino_acid_pair_ratio_ap <= 2 amino_acid_pair_ratio_ng > 13.1 amino_acid_pair_ratio_qh <= 8.5 amino_acid_pairs_ad <= 0 [hom( A ),classification( A ,epsilon_subdivision)] = 0 -> class 'Laterally acquirred elements' [0.889] Evaluation on test data (712 items): ecoli22 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insA_1' 'IS1 protein InsA' ecoli1319 5,1,2 Extrachromosomal Laterally acquirred elements Phage-related functions and prophages 'lar' 'restriction alleviation and modification enhancement' ecoli1 - 3,1,18 Metabolism of small molecules Amino acid biosynthesis Threonine 'thrL' 'thr operon leader peptide' ecoli866 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'lolA' 'periplasmic protein effects translocation of lipoproteins from inner membrane to outer' ecoli2979 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi22_5' 'IS2 protein' ecoli3749 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'b3837' 'twin arginine translocation part of sec-independent protein export' ecoli1350 - 1,6,1 Cell processes Adaptation Adaptations, atypical conditions 'hslJ' 'heat shock protein hslJ' ecoli3806 - 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'frvA' 'Sugar Specific PTS family fructose-specific IIA component' Test Accuracy: 3/8 (37.50%) Test Frequency class 'Laterally acquirred elements': 25/712 (3.51%) Test Significance: dev(5.22) ; prob(2.122416E-03) Application to new data (2167 items): ecoli3691 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3777' 'orf' ecoli2039 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2080' 'orf' ecoli1930 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1966' 'putative outer membrane protein' ecoli3726 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3814' 'orf' ecoli108 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ppdD' 'prelipin peptidase dependent protein' ecoli2688 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2748' 'orf' ecoli3371 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhhA' 'orf' ecoli1929 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1965' 'orf' ecoli285 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yagZ' 'orf' ecoli1523 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1552' 'cold shock-like protein' ecoli57 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yabQ' 'orf' ecoli2749 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2809' 'orf' ecoli372 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0380' 'orf' ecoli599 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0609' 'orf' ecoli1542 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ydfA' 'orf' ecoli613 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'cspE' 'negative regulator of cspA transcription (CspA is major cold shock protein) / with crcAB high copy promotes or protects chromosome condensation' ecoli1543 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ydfB' 'orf' ecoli963 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0989' 'cold shock-like protein' ecoli979 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1005' 'orf' ecoli3260 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yheA' 'orf' ecoli1529 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'cspF' 'cold shock protein' ecoli1548 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1578' 'orf' ecoli2584 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2638' 'orf' ecoli2187 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2229' 'orf' ecoli1532 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'rem' 'orf' ecoli2061 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2102' 'orf' ecoli4162 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b4273' 'putative transposase' Frequency rule on new data: 27/2167 (1.25%) Evaluation on training data (939 items): ecoli1373 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi22_2' 'IS22 protein 2' ecoli1955 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi22_3' 'IS2 protein' ecoli538 5,1,2 Extrachromosomal Laterally acquirred elements Phage-related functions and prophages 'b0548' 'similar to phage 82 and lambda proteins' ecoli267 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insA_3' 'IS1 protein InsA' ecoli684 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'b0701' 'small orf part of the RhsC element' ecoli353 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi22_1' 'IS22 protein 1' ecoli1862 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insA_5' 'IS1 protein InsA' Training Accuracy: 7/7 (100.00%) Training Frequency class 'Laterally acquirred elements': 40/939 (4.26%) Training Significance: dev(12.54) ; prob(2.545428E-10) Evaluation on validation data (471 items): ecoli257 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insA_2' 'IS1 protein InsA 2' ecoli4183 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insA_7' 'IS1 protein InsA' ecoli2797 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi22_4' 'IS2 protein' ecoli3367 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insA_6' 'IS1 protein InsA' Validation Accuracy: 4/4 (100.00%) Validation Frequency class 'Laterally acquirred elements': 26/471 (5.52%) Validation Significance: dev(8.27) ; prob(9.285596E-06) ------------------ Rule 49: (114/4, lift 4.8) amino_acid_ratio_g > 4.2 amino_acid_pair_ratio_yx <= 2.6 [hom( A ),classification( A ,salmonella)] = 1 [hom( A ),species( A ,paracoccus_denitrificans)] = 1 [hom( A ),e_val_gt( A ,0.0006),mol_wt_gt( A ,55220)] = 1 [hom( A ),mol_wt_lteq( A ,55220),classification( A ,streptococcaceae)] = 1 [hom( A ),mol_wt_lteq( A ,32892),classification( A ,zea)] = 0 [hom( A ),keyword( A ,inner_membrane),classification( A ,epsilon_subdivision)] = 1 -> class 'Transport/binding proteins' [0.957] Evaluation on test data (712 items): ecoli3646 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'pstB' 'ABC superfamily (atp_bind) ATP-binding component of high-affinity phosphate-specific ABC transport system' ecoli924 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0949' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli335 1,5,21 Cell processes Transport/binding proteins MFS family 'lacY' 'MFS family of transport protein galactoside permease (M protein)(1st module)' ecoli151 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'fhuC' 'ABC superfamily (atp_bind) ATP-binding component of hydroxymate-dependent iron transport' ecoli3338 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'gntT' 'high-affinity gluconate permease in GNT-I system' ecoli3967 - 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'nrfD' 'putative nitrate reductase formate dependent also paral putative STP family of transport protein' ecoli2711 1,5,21 Cell processes Transport/binding proteins MFS family 'b2771' 'MFS family of transport protein (3rd module (function unknown)' ecoli2240 - 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoH' 'NADH dehydrogenase I chain H' ecoli1485 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1514' 'ABC superfamily (membrane)paral putative membrane component of ABC transport system' ecoli889 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'msbA' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli1307 1,5,43 Cell processes Transport/binding proteins ArAAP family 'ydaH' 'ArAAP family p-aminobenzoyl-glutamate utilization paral putative pump protein (transport)(1st module)' ecoli470 1,5,21 Cell processes Transport/binding proteins MFS family 'fsr' 'MFS family of transport protein fosmidomycin resistance protein(2nd module)' ecoli3275 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yheS' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli746 1,5,11 Cell processes Transport/binding proteins DASS family 'b0770' 'DASS family of transport protein' ecoli1400 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'tehA' 'tellurite resistance; K+-tellurite ethidium and proflavin transport; membrane protein' ecoli3374 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ugpE' 'ABC superfamily (membrane)sn-glycerol 3-phosphate transport system integral membrane protein(1st module)' ecoli175 - 3,6,1 Metabolism of small molecules Fatty acid biosynthesis Fatty acid and phosphatidic acid biosynth 'cdsA' 'CDP-diglyceride synthase(2nd module)' ecoli112 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'aroP' 'APC family of transport protein aromatic amino acid transport protein' ecoli4210 1,5,19 Cell processes Transport/binding proteins GntP family 'gntP' 'GntP family of transport protein high affinity gluconate transporter/gluconate permease in gnt-iii system (2nd module)' ecoli818 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b0842' 'transmembrane multidrug/chloramphenicol efflux transporter (2nd module)' ecoli4120 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ytfT' 'ABC superfamily (membrane)paral putative membrane component' ecoli333 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'cynX' 'cyanate transport' ecoli1499 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ydeA' 'ABC superfamily (membrane)putative membrane component of ABC transport system appears to facilitate arabinose export contributes to control of arabinose regulon' ecoli785 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'glnQ' 'ABC superfamily (atp_bind) ATP-binding component of glutamine high-affinity ABC transport system(2nd module)' ecoli3462 1,5,36 Cell processes Transport/binding proteins STP family 'yhjV' 'STP family of transport protein' ecoli47 1,5,9 Cell processes Transport/binding proteins CPA2 family 'kefC' 'CPA2 family k+ efflux antiporter glutathione-regulated (2nd module)' ecoli3409 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b3486' 'ABC superfamily (membrance) paral putative membrane component of transport system (3rd module)' ecoli2921 1,5,32 Cell processes Transport/binding proteins PiT family 'pitB' 'PiT family low-affinity phosphate transport(1st module)' ecoli3525 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'lldP' 'L-lactate permease(1st module)' ecoli581 1,5,31 Cell processes Transport/binding proteins POT family 'ybdA' 'paral putative POT family of transport protein (1st module)' ecoli3980 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yjcV' 'ABC superfamily (membrane) membrane component of allose ABC transport system(1st module)' ecoli4176 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'fecE' 'ABC superfamily (atp_bind) ATP-binding component of citrate-dependent iron(III) transport protein' ecoli1467 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yddA' 'ABC superfamily (atp_bind) paral putative ATP-binding module (2nd module)' ecoli3200 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yhdY' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli252 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'ykfD' 'APC family of transport protein S-methylmethionine permease' ecoli2622 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'proV' 'ABC superfamily (atp_bind) ATP-binding component of transport system for glycine betaine and proline(1st module)' ecoli3961 1,5,35 Cell processes Transport/binding proteins SSS family 'yjcG' 'SSS family transport protein' ecoli3643 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'bglF' 'Sugar Specific PTS family beta-glucosides enzyme II cryptic (2nd module eiia (ei interaction)?)' ecoli1380 - 3,3,11 Metabolism of small molecules Central intermediary metabolism Nucleotide interconversions 'b1409' 'putative phosphatidate cytidiltransferase(2nd module)' ecoli3125 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b3195' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli2324 1,5,21 Cell processes Transport/binding proteins MFS family 'emrY' 'MFS family of transport protein multidrug resistance protein y (2nd module)' ecoli662 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'nagE' 'Sugar Specific PTS family n-acetylglucosamine-specific enzyme IIABC (3rd module)' ecoli796 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0820' 'paral putative ATP-binding component of transport system' ecoli3587 1,5,21 Cell processes Transport/binding proteins MFS family 'uhpT' 'MFS family of transport protein hexose phosphate transport protein (2nd module)' ecoli644 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'gltJ' 'ABC superfamily (membrane) glutamate/aspartate transport system permease' ecoli1089 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1116' 'ABC superfamily (membrane) paral putative membrane component of ABC transport system' ecoli3293 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'yhfM' 'APC family paral putative amino-acid transport protein (2nd module)' ecoli2655 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'ascF' 'PTS family enzyme II ABC (asc) cryptic transports specific beta-glucosides' ecoli4017 1,5,12 Cell processes Transport/binding proteins Dcu family 'dcuB' 'Dcu family anaerobic C4-dicarboxylate transporter' ecoli602 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'b0612' 'citrate carrier transport citrate trading for succinate export' ecoli3380 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'livH' 'ABC superfamily (membrane) membrane component of high-affinity branched-chain amino acid ABC transport system(2nd module)' ecoli2662 - 3,5,4 Metabolism of small molecules Energy metabolism, carbon Fermentation 'hycD' 'membrane-spanning protein of hydrogenase 3 (part of FHL complex)' ecoli486 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ybbA' 'ABC superfamily (atp_bind) putative' ecoli2538 1,5,21 Cell processes Transport/binding proteins MFS family 'kgtP' 'MFS family of transport protein alpha-ketoglutarate permease(1st module)' ecoli3580 1,5,21 Cell processes Transport/binding proteins MFS family 'yicK' 'MFS family of transport protein two-module paral putative transport protein (2nd module)' ecoli2198 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'glpT' 'sn-glycerol-3-phosphate permease' ecoli566 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'pheP' 'phenylalanine-specific transport system' ecoli3201 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yhdZ' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli3579 1,5,16 Cell processes Transport/binding proteins GPH family 'yicJ' 'GPH family paral putative transport protein' ecoli1827 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'yebI' 'inner memrane component of a high affininty Zn transport system' ecoli2264 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'hisP' 'ABC superfamily (atp_bind) ATP-binding component of histidine ABC transport system' ecoli578 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'fepC' 'ABC superfamily (atp_bind) ATP-binding component of ferric enterobactin transport(2nd module)' ecoli786 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'glnP' 'glutamine high-affinity transport system; membrane component(1st module)' ecoli3043 1,5,36 Cell processes Transport/binding proteins STP family 'yhaO' 'STP family of transport protein (1st module)' ecoli1164 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b1191' 'PUTATIVE NA(+)/H(+) EXCHANGER according to SwissProt version 38 the orf starts at a methionine 42 aa upstream of b 1191 start' ecoli1514 1,5,21 Cell processes Transport/binding proteins MFS family 'b1543' 'MFS family of transport protein (1st module)' ecoli3188 1,5,35 Cell processes Transport/binding proteins SSS family 'panF' 'SSS family transport protein sodium/pantothenate symporter(1st module)' ecoli1633 1,5,20 Cell processes Transport/binding proteins MATE family 'ydhE' 'MATE family of transport protein(2nd module)' ecoli2357 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'xapB' 'xanthosine permease' ecoli2421 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'acrD' 'sensitivity to acriflavine integral membrane protein possible efflux pump' ecoli1261 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'sapF' 'ABC superfamily (atp_bind) ATP-binding protein of peptide ABC transport system(2nd module)' ecoli358 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0366' 'ABC superfamily (atp_bind) ATP-binding component of a taurine transport system' ecoli1097 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'potC' 'ABC superfamily (membrane) membrane component of spermidine/putrescine ABC transport system(2nd module)' ecoli67 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yabK' 'ABC superfamily (membrane) membrane component of thiamine ABC transport system(1st module)' ecoli3981 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yjcW' 'ABC superfamily (atp_bind) ATP-binding component of allose transport system (2nd module)' ecoli2497 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b2546' 'ABC superfamily (membrane)paral putative membrane component of ABC transport system (2nd module)' ecoli3594 1,5,21 Cell processes Transport/binding proteins MFS family 'emrD' 'MFS family of transport protein 2-module integral membrane pump; multidrug resistance (2nd module)' ecoli4277 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yjjK' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system (2nd module)' ecoli2034 1,5,33 Cell processes Transport/binding proteins RNDfamily 'b2075' 'RND family of transport protein paral putative outer membrane receptor' ecoli45 1,5,21 Cell processes Transport/binding proteins MFS family 'yaaU' 'MFS family transport protein' ecoli1826 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1858' 'ABC superfamily (atp_bind) ATP-binding component of a high affinity Zn transport system(1st module)' ecoli840 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'artP' 'ABC superfamily (atp&memb) ATP-binding component of 3rd arginine transport system(2nd module)' ecoli4155 1,5,19 Cell processes Transport/binding proteins GntP family 'yjgT' 'GntP family l-idonate transporter (2nd module)' ecoli2373 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'cysA' 'ABC superfamily (atp_bind) ATP-binding component of sulfate permease A protein of ABC transport; chromate resistance (1st module)' ecoli3026 1,5,21 Cell processes Transport/binding proteins MFS family 'exuT' 'MFS family of transport protein transport of hexuronates (2nd module)' ecoli1875 1,5,43 Cell processes Transport/binding proteins ArAAP family 'tyrP' 'ArAAP family tyrosine-specific transport system' ecoli328 1,5,25 Cell processes Transport/binding proteins NCS1 family 'codB' 'NCS1 family transport protein cytosine permease/transport(2nd module)' ecoli3971 1,5,10 Cell processes Transport/binding proteins DAACS family 'gltP' 'DAACS family of transport protein glutamate-aspartate symport protein' ecoli3131 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yhbG' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli1022 - 1,6,2 Cell processes Adaptation Osmotic adaptation 'mdoH' 'membrane glycosyltransferase; synthesis of membrane-derived oligosaccharide (MDO)/synthesis of OPGs (osmoregulated periplasmic glucans)(2nd module)' ecoli2141 1,5,21 Cell processes Transport/binding proteins MFS family 'bcr' 'MFS family of transport protein bicyclomycin resistance protein; transmembrane protein (2nd module)' ecoli127 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yadG' 'ABC superfamily (atp_bind) ATP-binding component of transport protein (1st module)' ecoli2487 1,5,21 Cell processes Transport/binding proteins MFS family 'b2536' 'MFS family of transport protein (1st module)' ecoli3959 1,5,8 Cell processes Transport/binding proteins CPA1 family 'yjcE' 'CPA1 family PUTATIVE NA(+)/H(+) EXCHANGER YJCE(1st module)' ecoli1455 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1484' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli420 - 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'cyoE' 'protohaeme IX farnesyltransferase (haeme O biosynthesis)' ecoli3952 - 2,2,3 Macromolecule metabolism Macromolecule synthesis, modification DNA - replication, repair, restraction/modification 'uvrA' 'excision nuclease subunit (3rd module prob. DNA binding)' ecoli770 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0794' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli807 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0831' 'paral putative membrane component of transport system' ecoli254 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yagC' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' Test Accuracy: 89/100 (89.00%) Test Frequency class 'Transport/binding proteins': 151/712 (21.21%) Test Significance: dev(16.58) ; prob(1.216669E-47) Application to new data (2167 items): ecoli1604 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1634' 'orf' ecoli3445 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhjD' 'orf' ecoli3170 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhcP' 'orf' ecoli487 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0496' 'putative oxidoreductase' ecoli2634 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2689' 'orf' ecoli821 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0845' 'paral putative transport protein (2nd module bind phosphorylated sugar? )' ecoli3606 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yidE' 'paral putative transport protein(1st module)' ecoli2215 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2257' 'orf(2nd module)' ecoli3581 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yicL' 'putative permease transporter' ecoli3028 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3095' 'orf' ecoli2444 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2493' 'paral putative transport protein' ecoli4009 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b4115' 'putative amino acid/amine transport protein cryptic' ecoli1575 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1605' 'putative arginine/ornithine antiporter' ecoli1562 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1592' 'orf' ecoli3468 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhjW' 'orf (2nd module)' ecoli2329 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2372' 'putative receptor protein' ecoli3397 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yhhT' 'paral putative transport protein (2nd module)' ecoli4034 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjeH' 'putative transport' ecoli3437 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yhiV' 'paral putative membrane component of transport system (3rd module)' ecoli3849 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yijE' 'orf (2nd module)' ecoli3780 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yihN' 'orf' ecoli1221 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'kch' 'putative potassium channel protein' ecoli155 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yadQ' 'putative channel transporter' ecoli2147 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yejM' 'putative sulfatase' ecoli2095 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yohD' 'orf' ecoli3419 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhiP' 'orf' ecoli3357 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3434' 'orf' ecoli2821 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2885' 'orf' ecoli1766 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1798' 'paral putative transport protein' ecoli764 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0788' 'orf (2nd module)' ecoli3739 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yigM' 'paral putative transport protein (2nd module)' ecoli980 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1006' 'putative transport protein(2nd module)' ecoli2943 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yghB' 'orf' ecoli2997 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ygjE' 'paral putative DASS family of transport protein' ecoli3585 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yicO' 'orf (2nd module)' ecoli1658 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1690' 'paral putative MFS family of transport protein' ecoli1720 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1752' 'orf' ecoli3114 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhbE' 'orf' ecoli1923 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yedA' 'orf (1st module)' ecoli1042 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'mviN' 'putative virulence factor' ecoli1504 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ydeD' 'orf' ecoli4221 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjiJ' 'paral putative transport protein (2nd module)' ecoli1301 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1330' 'orf(2nd module)' ecoli2250 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2292' 'putative transport protein' ecoli3600 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yidK' 'putative cotransporter' ecoli3731 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'rarD' 'chloramphenicol resistance' ecoli945 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yccA' 'putative carrier/transport protein(2nd module)' ecoli1505 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ydeF' 'paral putative transport protein (1st module)' ecoli502 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0511' 'orf' ecoli1743 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1775' 'paral putative transport protein (1st module)' ecoli3706 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yifJ' 'putative cytochrome' ecoli1718 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1750' 'orf' ecoli784 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0808' 'pral putative transport protein (2nd module)' ecoli3083 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yraQ' 'orf' ecoli2715 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2775' 'orf' ecoli2858 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yggA' 'orf' ecoli4083 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjfS' 'orf' ecoli789 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ybiF' 'orf' ecoli2088 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yehX' 'paral putative ATP-binding component of transport system' ecoli2305 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfdC' 'putative transport' ecoli2006 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2047' 'putative colanic acid biosynthsis UDP-glucose lipid carrier transferase/glucose-1-phosphate transferase in colanic acid gene cluster' ecoli3576 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yicE' 'putative transport protein' ecoli4151 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjgP' 'orf(1st module)' ecoli2204 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2246' 'putative transport protein' ecoli3126 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yrbG' 'orf' ecoli320 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0328' 'paral putative transport protein' ecoli2285 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfcA' 'putative structural protein' ecoli3021 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ygjT' 'orf' ecoli1486 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1515' 'paral putative membrane component of ABC transport system' ecoli2349 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2392' 'putative transport system permease(1st module)' ecoli791 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0815' 'orf (2nd module)' ecoli2498 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2547' 'paral putative ATP-binding component of transport system' ecoli7 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yaaJ' 'putative inner membrane transport protein' ecoli504 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0513' 'putative transport(2nd module)' ecoli4243 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjiY' 'putative carbon starvation protein' ecoli1943 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1981' 'shikimate and dehydroshikimate permease (2nd module)' ecoli4152 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjgQ' 'orf(1st module)' ecoli1697 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1729' 'part of a kinase(1st module paral putative tdomain shared with transporter)' ecoli1454 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1483' 'paral putative ATP-binding component of transport system' ecoli2322 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'dsdX' 'transport system permease (serine?)' ecoli2275 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'dedA' 'orf' ecoli873 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ycaD' 'paral putative transport protein (1st module)' ecoli4245 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b4356' 'paral putative transport protein cryptic orf joins former yjiZ and yjjL' ecoli1038 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1065' 'orf' ecoli2361 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfeH' 'putative cytochrome oxidase' ecoli1759 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1791' 'putative amino acid/amine transport protein (3rd module)' ecoli4049 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjeM' 'paral putative amino-acid transport protein' ecoli262 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yagG' 'paral putative transport protein' ecoli2729 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2789' 'paral putative membrane component of transport system (2nd module)' ecoli2256 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2298' 'putative S-transferase' ecoli794 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0818' 'orf' ecoli3751 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yigU' 'integral membrane protein part of sec-independent protein export' ecoli3958 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjcD' 'orf (2nd module)' Frequency rule on new data: 93/2167 (4.29%) Evaluation on training data (939 items): ecoli4024 1,5,31 Cell processes Transport/binding proteins POT family 'b4130' 'POT family of transport protein paral putative transport protein (3rd module)' ecoli2057 1,5,21 Cell processes Transport/binding proteins MFS family 'b2098' 'MFS family of transport protein (2nd module)' ecoli3359 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'gntU_1' 'split gene low-affinity gluconate transport permease protein in GNT-I system first part of fragment 1(1st module)' ecoli855 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0879' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli3425 1,5,4 Cell processes Transport/binding proteins Ars family 'arsB' 'Ars family arsenical pump membrane protein(2nd module)' ecoli1099 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'potA' 'ABC superfamily (atp_bind) ATP-binding component of spermidine/putrescine ABC transport system (1st module)' ecoli3489 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'xylG' 'ABC superfamily (atp_bind) ATP-binding component of D-xylose ABC transport system(2nd module)' ecoli1723 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1755' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli3647 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'pstA' 'ABC superfamily (membrane) membrane component of high-affinity phosphate-specific ABC transport system (2nd module)' ecoli2265 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'hisM' 'ABC superfamily (membrane)histidine transport membrane protein m (2nd module transport function )' ecoli3991 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'phnK' 'ABC superfamily (atp_bind) ATP-binding component of phosphonate ABC transportbelieved to be part of carbon-phosphorus (C-P) lyase in phosphonate metabolism' ecoli153 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'fhuB' 'ABC superfamily (membrane) split gene C-term module hydroxamate-dependent iron uptake (2nd module iron uptake )' ecoli1659 1,5,21 Cell processes Transport/binding proteins MFS family 'b1691' 'MFS family of transport protein' ecoli3396 1,5,21 Cell processes Transport/binding proteins MFS family 'yhhS' 'MFS family of transport protein (2nd module)' ecoli1566 1,5,21 Cell processes Transport/binding proteins MFS family 'b1596' 'MFS familty transport protein (2nd module)' ecoli3154 1,5,21 Cell processes Transport/binding proteins MFS family 'nanT' 'MFS family of transport protein sialic acid transporter cryptic in K12?(1st module)' ecoli3386 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ftsE' 'ABC superfamily (atp_bind) ATP-binding component of a membrane-associated complex involved in cell division' ecoli66 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yabJ' 'ABC superfamily (atp_bind) ATP-binding component of thiamine ABC transport system' ecoli2736 1,5,36 Cell processes Transport/binding proteins STP family 'sdaC' 'STP family of transport protein serine transporter' ecoli3403 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'nikE' 'ABC superfamily (stp_bind) ATP-binding component of nickel ABC transport system probably couples energy to transport system' ecoli3783 1,5,16 Cell processes Transport/binding proteins GPH family 'yihP' 'GPH family paral putative transport protein' ecoli1650 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1682' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli2680 1,5,19 Cell processes Transport/binding proteins GntP family 'b2740' 'GntP family of transport protein function unknown (3rd module)' ecoli3782 1,5,16 Cell processes Transport/binding proteins GPH family 'b3876' 'GPH family paral putative transport protein (2nd module)' ecoli1267 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b1296' 'APC family paral putative amino-acid transport protein' ecoli2631 1,5,21 Cell processes Transport/binding proteins MFS family 'emrB' 'MFS family of transport protein multidrug resistance; probably membrane translocase(1st module)' ecoli3049 1,5,36 Cell processes Transport/binding proteins STP family 'tdcC' 'STP family of transport protein anaerobically inducible L-threonine/ L-serine permease' ecoli3373 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ugpC' 'ABC superfamily (atp_bind) ATP-binding component of sn-glycerol 3-phosphate ABC transport system (1st module)' ecoli1264 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'sapB' 'ABC superfamily (membrane) membrane component of peptide ABC transport system' ecoli3670 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'rbsA' 'ABC superfamily (atp_bind) ATP-binding component of d-ribose high-affinity transport system (2nd module)' ecoli1026 1,5,21 Cell processes Transport/binding proteins MFS family 'yceE' 'MFS family of transport protein (2nd module)' ecoli1586 1,5,16 Cell processes Transport/binding proteins GPH family 'uidB' 'GPH family glucuronide permease' ecoli425 1,5,21 Cell processes Transport/binding proteins MFS family 'ampG' 'MFS family of transport protein ampicillin resistance (1st module)' ecoli2115 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'lysP' 'APC family lysine-specific permease (2nd module)' ecoli1090 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1117' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli4226 1,5,21 Cell processes Transport/binding proteins MFS family 'yjiO' 'MFS family of transport protein (1st module)' ecoli1179 1,5,38 Cell processes Transport/binding proteins SulP family 'ychM' 'SulP family transport protein (1st module)' ecoli2036 1,5,21 Cell processes Transport/binding proteins MFS family 'b2077' 'MFS family of transport protein (1st module)' ecoli675 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'potE' 'APC family putrescine-lyase antiporter' ecoli2608 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'gabP' 'transport permease protein of gamma-aminobutyrate' ecoli3157 1,5,13 Cell processes Transport/binding proteins DcuC 'yhcL' 'DcuC family of transport protein (2nd module)' ecoli643 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'gltK' 'ABC superfamily (membrane) glutamate/aspartate transport (1st module)' ecoli369 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'sbmA' 'ABC superfamily (atp&memb) sensitivity to microcin B17; methylmalonyl-CoA mutase (mcm); ATP-binding and membrane component' ecoli1159 1,5,27 Cell processes Transport/binding proteins NhaA family 'nhaB' 'NhaB family of transport protein Na+/H+ antiporter regulator of intracellular pH(1st module)' ecoli3675 1,5,21 Cell processes Transport/binding proteins MFS family 'yieO' 'MFS family of tranport protein (1st mdule)' ecoli908 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ycbE' 'paral putative ATP-binding component of transport system' ecoli3466 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'dppB' 'ABC superfamily (membrane) membrane component of dipeptide ABC transport system; permease protein 1(2nd module)' ecoli1262 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'sapD' 'ABC superfamily (atp_bind) ATP-binding protein of peptide transport system(2nd module) affects potassium transport;' ecoli3671 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'rbsC' 'ABC superfamily (membrane) ABC superfamily of transport protein D-ribose high-affinity ABC transport system(1st module ATP-binding subunit)' ecoli1705 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'celB' 'PTS family sugar specific enzyme II for cellobiose arbutin and salicin' ecoli453 1,5,33 Cell processes Transport/binding proteins RNDfamily 'acrB' 'RND family of transport protein acridine efflux pump(2nd module)' ecoli345 1,5,21 Cell processes Transport/binding proteins MFS family 'b0353' 'MFS family transport protein (2nd module function unknown)' ecoli394 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b0402' 'APC family of transport protein proline permease transport protein' ecoli3059 1,5,21 Cell processes Transport/binding proteins MFS family 'yhaU' 'MFS family of transport protein (D)-glucarate or galactarate transporter (1st module)' ecoli3463 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'dppF' 'ABC superfamily (atp_bind) ATP-binding component of a dipeptide transport system(1st module)' ecoli2129 1,5,21 Cell processes Transport/binding proteins MFS family 'yeiO' 'MFS family proton-coupled sugar efflux pump transport selective monosaccharides and disaccharides narrower substr. specificity than SetA(2nd module)' ecoli4026 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'cadB' 'APC family transport of lysine/cadaverine(1st module)' ecoli989 1,5,35 Cell processes Transport/binding proteins SSS family 'putP' 'SSS family transport protein major sodium/proline symporter' ecoli2139 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yejF' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli2448 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'uraA' 'uracil transport' ecoli3761 1,5,39 Cell processes Transport/binding proteins Trk system 'trkH' 'Trk system potassium uptake requires TrkE' ecoli861 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'cydC' 'ABC superfamily (atp&memb) ATP-binding and membrane components of cytochrome-related ABC transport(2nd module)' ecoli2899 1,5,21 Cell processes Transport/binding proteins MFS family 'nupG' 'MFS family of transport protein transport of nucleosides (2nd module)' ecoli3273 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'kefB' 'K+ efflux; NEM-activable K+/H+ antiporter' ecoli3379 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'livM' 'ABC superfamily (membrane) membrane component of high-affinity branched-chain amino acid ABC transport system (2nd module)' ecoli3022 1,5,10 Cell processes Transport/binding proteins DAACS family 'ygjU' 'DAACS family Na+/serine (threonine) symporter' ecoli3011 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'ygjI' 'APC family paral putative amino-acid transport protein' ecoli2035 1,5,33 Cell processes Transport/binding proteins RNDfamily 'b2076' 'RND family of transport protein paral putative outer membrane receptor' ecoli3630 1,5,43 Cell processes Transport/binding proteins ArAAP family 'tnaB' 'ArAAP family low affinity tryptophan permease' ecoli3378 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'livG' 'ABC superfamily (atp_bind) ATP-binding component of high-affinity branched-chain amino acid ABC transport system' ecoli3668 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'kup' 'low affinity potassium transport system' ecoli4121 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yjfF' 'ABC superfamily (membrane) ABC superfamily of transport protein (1st module membrance component)' ecoli3648 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'pstC' 'ABC superfamily (membrane) membrane component of high-affinity phosphate-specific ABC transport system (2nd module)' ecoli393 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'brnQ' 'branched chain; mutants valine and o-methylthreonine resistant glyclyvaline sensitive; transport system I for Ile Leu and Val' ecoli1218 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'oppF' 'ABC superfamily (atp_bind) ATP-binding protein of oligopeptide ABC transport system' ecoli1414 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1443' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli862 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'cydD' 'ABC superfamily (atp&memb) ATP-binding and membrane components of cytochrome-related ABC transport Zn sensitive(2nd module)' ecoli388 1,5,21 Cell processes Transport/binding proteins MFS family 'araJ' 'MFS family of transport protein involved in either transport or processing of arabinose polymers (2nd module function unknown)' ecoli1098 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'potB' 'ABC superfamily (membrane) membrane component of spermidine/putrescine ABC transport system(2nd module)' ecoli4178 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'fecC' 'ABC superfamily (membrane) citrate-dependent iron(III) transport protein (2nd module)' ecoli1463 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'xasA' 'APC family acid sensitivity protein putative glutamate:gamma-aminobutyric acid antiporter (GadC)(2nd module)' ecoli2343 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'b2386' 'Sugar Specific paral putative membrane component of transport system' ecoli2138 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yejE' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli469 1,5,9 Cell processes Transport/binding proteins CPA2 family 'ybaL' 'CPA2 family transport protein' ecoli3287 1,5,21 Cell processes Transport/binding proteins MFS family 'yhfC' 'MFS family of transport protein paral putative transport protein' ecoli2375 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'cysU' 'ABC superfamily (membrane) membrane component of sulfate thiosulfate ABC transport system (2nd module)' ecoli874 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b0899' 'APC family paral putative amino-acid transport protein' ecoli40 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'caiT' 'probable carnitine transporter' ecoli2878 1,5,21 Cell processes Transport/binding proteins MFS family 'galP' 'MFS family of transport protein galactose-proton symport of transport system (2nd module)' ecoli2005 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'b2046' 'probable export protein /export to periplasm in colanic acid gene cluster' ecoli2159 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ccmA' 'ABC superfamily (atp_bind) ATP-binding component of heme exporter A heme exporter protein A cytochrome c-type biogenesis protein' ecoli2108 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'mglA' 'ABC superfamily (atp_bind) ATP-binding component of methyl-galactoside transport and galactose taxis (2nd module)' ecoli2741 1,5,21 Cell processes Transport/binding proteins MFS family 'fucP' 'MFS family of transport protein fucose permease(1st module)' ecoli3711 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'yifK' 'APC family paral putative amino-acid transport protein' ecoli3402 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'nikD' 'ABC superfamily (atp_bind) ATP-binding component of nickel ABC transport system probably couples energy to transport system(2nd module)' ecoli1283 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1312' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli2181 - 3,4,4 Metabolism of small molecules Degradation of small molecules Fatty acids 'atoB' 'short chain fatty acids transporter' ecoli1882 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1917' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli3408 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yhhJ' 'ABC superfamily (membrane)paral putative transport system membrane (2nd module)' ecoli481 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0490' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli3469 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'yhjX' 'putative resistance protein' ecoli19 1,5,27 Cell processes Transport/binding proteins NhaA family 'nhaA' 'NhaA family of transport protein Na+/H antiporter pH dependent(1st module)' ecoli3583 1,5,21 Cell processes Transport/binding proteins MFS family 'yicM' 'MFS family of tranport protein (1st mdule)' ecoli3855 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'frwC' 'PTS system fructose-like IIC component first module overlaps second(2nd module)' ecoli736 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'modF' 'ABC superfamily (atp_bind) ATP-binding component of molybdenum transport system (2nd module)' ecoli1215 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'oppB' 'ABC superfamily (membrane) membrane component of oligopeptide ABC transport system(2nd module)' ecoli1440 1,5,21 Cell processes Transport/binding proteins MFS family 'narU' 'MFS family of transport protein nitrate sensor-transmitter protein anaerobic respiratory path(1st module)' ecoli2443 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b2492' 'membrane protein formate transporter of hyf operon (formate channel 2)' ecoli1334 1,5,39 Cell processes Transport/binding proteins Trk system 'trkG' 'Trk system potassium uptake' ecoli2107 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'mglC' 'ABC superfamily (membrane) membrane component of methyl-galactoside ABC transport system and galactose taxis(1st module)' ecoli1679 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'btuC' 'ABC superfamily (membrane) membrane component of vitamin B12 ABC transport system' ecoli440 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'mdlA' 'ATP-binding component of a transport system (2nd module)' ecoli477 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b0486' 'APC family of transport protein amino-acid transport protein' ecoli4185 1,5,19 Cell processes Transport/binding proteins GntP family 'yjhF' 'GntP family of transport protein (1st module)' Training Accuracy: 110/114 (96.49%) Training Frequency class 'Transport/binding proteins': 187/939 (19.91%) Training Significance: dev(20.47) ; prob(2.247935E-71) Evaluation on validation data (471 items): ecoli4014 1,5,16 Cell processes Transport/binding proteins GPH family 'melB' 'GPH family melibiose permease II' ecoli3929 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'malK' 'ABC superfamily (atp_bind) ATP-binding component of transport system for maltose phenotypic repressor of mal operon(1st module)' ecoli837 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'artM' 'arginine 3rd transport system permease protein' ecoli441 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'mdlB' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli419 1,5,21 Cell processes Transport/binding proteins MFS family 'b0427' 'MFS family transport protein' ecoli4119 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ytfS' 'ABC superfamily (atp_bind) putative ATP-binding component of a transport system' ecoli3990 - 3,3,13 Metabolism of small molecules Central intermediary metabolism Phosphorus compounds 'phnL' 'ABC superfamily (atp_bind) ATP-binding component of phosphonate ABC transport believed to be part of carbon-phosphorus (C-P) lyase in phosphonate metabolism' ecoli1074 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'ptsG' 'Sugar Specific PTS family glucose-specific IIBCcomponent (3rd module hydrophilic second phosphorylation domain) mutant form transports D-ribose' ecoli1216 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'oppC' 'ABC superfamily (membrane)homolog of Salmonella oligopeptide transport permease protein(2nd module)' ecoli3926 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'malG' 'ABC superfamily (membrane) membrane component of maltose ABC transport system (2nd module)' ecoli3375 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ugpA' 'ABC superfamily (membrane) sn-glycerol 3-phosphate integral membrane protein ABC transport system' ecoli2778 1,5,21 Cell processes Transport/binding proteins MFS family 'araE' 'MFS family of transport protein low-affinity L-arabinose transport system proton symport protein(1st module)' ecoli1289 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1318' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli4098 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'cycA' 'APC family transport of D-alanine D-serine and glycine (2nd module)' ecoli2623 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'proW' 'ABC superfamily (membrane) membrane component of high-affinity ABC transport system for glycine betaine and proline (2nd module)' ecoli1196 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'narK' 'nitrite extrusion protein(2nd module)' ecoli2089 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yehY' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli1627 1,5,21 Cell processes Transport/binding proteins MFS family 'b1657' 'MFS family of transport protein (2nd module)' ecoli2772 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'ygeD' 'putative resistance proteins' ecoli1630 1,5,21 Cell processes Transport/binding proteins MFS family 'ydhC' 'MFS family transport protein (2nd module)' ecoli70 1,5,21 Cell processes Transport/binding proteins MFS family 'yabM' 'MFS family of transport protein proton-coupled beta-galactosidase/sugar efflux pump ? role in lactose metabolism (2nd module)' ecoli4130 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'treB' 'PTS family enzyme II trehalose specific (maltose may be transported)' ecoli4168 1,5,21 Cell processes Transport/binding proteins MFS family 'yjhB' 'MFS family of tranport protein (1st module)' ecoli1973 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'yeeF' 'APC family paral putative amino-acid transport protein' ecoli2929 - 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'hybB' 'probable cytochrome Ni/Fe component of hydrogenase-2(1st module)' ecoli3938 1,5,20 Cell processes Transport/binding proteins MATE family 'dinF' 'MATE family of transport protein; also DNA-damage-inducible protein F;induced by UV and mitomycin C; SOS lexA regulon(2nd module)' ecoli1282 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1311' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli3464 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'dppD' 'ABC superfamily (atp_bind) ATP-binding component of dipeptide tABCransport system(2nd module)' ecoli838 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'artQ' 'ABC superfamily (membrane) membrane component of 3rd arginine ABC transport system' ecoli1796 1,5,21 Cell processes Transport/binding proteins MFS family 'b1828' 'MFS family of transport protein (2nd module)' ecoli642 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'gltL' 'ABC superfamily (atp_bind) ATP-binding protein of glutamate/aspartate transport system' ecoli1424 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b1453' 'L-asparagine permease (2nd module)' ecoli3377 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'livF' 'ABC superfamily (atp_bind) ATP-binding component of leucine ABC transport system' ecoli1677 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'btuD' 'ABC superfamily (atp_bind) ATP-binding component of vitamin B12 ABC transport system(2nd module)' ecoli3490 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'xylH' 'ABC superfamily (membrane)d-xylose transport permease (2nd module might interact with atp hydrolysing subunit )' ecoli3465 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'dppC' 'ABC superfamily (membrane) membrane component of dipeptide ABC transport system; permease protein 2 (2nd module)' ecoli2782 1,5,36 Cell processes Transport/binding proteins STP family 'b2845' 'STP family of transport protein' ecoli3223 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'prlA' 'protein secretion inner membrane preprotein translocase SecY subunit interacts with SecE (1st module)' ecoli3925 1,5,21 Cell processes Transport/binding proteins MFS family 'xylE' 'MFS family of tranport protein xylose-proton symport (2nd module)' ecoli3612 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'yidT' 'D-galactonate transport' ecoli2909 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b2975' 'LctP transporter L-lactate permease homologue' ecoli199 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'abc' 'ABC superfamily (atp_bind) ATP-binding component of ABC transport system(1st module)' ecoli3588 1,5,21 Cell processes Transport/binding proteins MFS family 'uhpC' 'regulator of uhpT (1st module)' ecoli4177 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'fecD' 'ABC superfamily (membrane) membrane component of citrate-dependent ABC transport system of iron' ecoli1868 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'araG' 'ABC superfamily (atp_bind) ATP-binding component of high-affinity l-arabinose transport system (2nd module)' ecoli1867 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b1899' 'split high-affinity L-arabinose transport system; membrane protein fragment 1' ecoli1996 - 4,1,4 Structural elements Cell envelop Surface polysaccharides & antigens 'rfbX' 'hydroponic protein o-antigen (3rd module)' ecoli4005 1,5,21 Cell processes Transport/binding proteins MFS family 'proP' 'MFS family of tranport protein low-affinity constitutive transport system; proline permease II transports proline and betaine under conditions of hyperosmolarity(2nd module)' ecoli741 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'modC' 'ABC superfamily (atp_bind) ATP-binding component of molybdate ABC transport (1st module)' ecoli1591 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'malX' 'Sugar Specific PTS family maltose and glucose-specific ii abc (2nd module hydrophilic second phosphorylation domain)' ecoli3631 1,5,21 Cell processes Transport/binding proteins MFS family 'yidY' 'MFS family of tranport protein (1st mdule)' ecoli3093 1,5,43 Cell processes Transport/binding proteins ArAAP family 'mtr' 'ArAAP family tryptophan-specific transport protein' ecoli1724 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1756' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli831 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'potG' 'ABC superfamily (atp_bind) ATP-binding component of putrescine ABC transport system(1st module)' ecoli2280 1,5,21 Cell processes Transport/binding proteins MFS family 'b2322' 'MFS family of transport protein paral putative (2nd module)' ecoli4000 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'phnC' 'ABC superfamily (atp_bind) ATP-binding component of phosphonate ABC transport system' ecoli1412 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1441' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli2380 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'b2429' 'Sugar Specific paral putative PTS system enzyme II' ecoli4031 1,5,12 Cell processes Transport/binding proteins Dcu family 'dcuA' 'Dcu family anaerobic dicarboxylate transport' ecoli2169 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yojI' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli2818 1,5,13 Cell processes Transport/binding proteins DcuC 'b2882' 'DcuC family paral putative transport protein' ecoli1217 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'oppD' 'ABC superfamily (atp_bind) ATP-binding protein of oligopeptide ABC transport system' ecoli1189 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'chaA' 'sodium-calcium/proton antiporter' ecoli3709 - 3,3,18 Metabolism of small molecules Central intermediary metabolism Sugar-nucleotide biosynthesis, conversions 'rffT' 'synthesis of enterobacterial common antigen (ECA): TDP-Fuc4NAc:lipidII transferase(1st module)' ecoli692 1,5,31 Cell processes Transport/binding proteins POT family 'b0709' 'POT family of transport protein (1st module)' ecoli3451 1,5,10 Cell processes Transport/binding proteins DAACS family 'dctA' 'DAACS family of transport protein uptake of C4-dicarboxylic acids' ecoli2824 1,5,26 Cell processes Transport/binding proteins NCS2 family 'b2888' 'NCS2 family paral putative transport protein' ecoli1737 1,5,21 Cell processes Transport/binding proteins MFS family 'ydjE' 'MFS family of transport protein (1st module)' Validation Accuracy: 62/68 (91.18%) Validation Frequency class 'Transport/binding proteins': 104/471 (22.08%) Validation Significance: dev(13.74) ; prob(5.222408E-34) ------------------ Rule 50: (85/6, lift 4.6) [hom( A ),classification( A ,carnivora)] = 1 [hom( A ),classification( A ,corynebacteriaceae)] = 1 [hom( A ),keyword( A ,transmembrane),classification( A ,kinetoplastida)] = 1 -> class 'Transport/binding proteins' [0.920] Evaluation on test data (712 items): ecoli335 1,5,21 Cell processes Transport/binding proteins MFS family 'lacY' 'MFS family of transport protein galactoside permease (M protein)(1st module)' ecoli3338 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'gntT' 'high-affinity gluconate permease in GNT-I system' ecoli2711 1,5,21 Cell processes Transport/binding proteins MFS family 'b2771' 'MFS family of transport protein (3rd module (function unknown)' ecoli1485 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1514' 'ABC superfamily (membrane)paral putative membrane component of ABC transport system' ecoli1307 1,5,43 Cell processes Transport/binding proteins ArAAP family 'ydaH' 'ArAAP family p-aminobenzoyl-glutamate utilization paral putative pump protein (transport)(1st module)' ecoli746 1,5,11 Cell processes Transport/binding proteins DASS family 'b0770' 'DASS family of transport protein' ecoli3374 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ugpE' 'ABC superfamily (membrane)sn-glycerol 3-phosphate transport system integral membrane protein(1st module)' ecoli112 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'aroP' 'APC family of transport protein aromatic amino acid transport protein' ecoli4210 1,5,19 Cell processes Transport/binding proteins GntP family 'gntP' 'GntP family of transport protein high affinity gluconate transporter/gluconate permease in gnt-iii system (2nd module)' ecoli818 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b0842' 'transmembrane multidrug/chloramphenicol efflux transporter (2nd module)' ecoli4120 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ytfT' 'ABC superfamily (membrane)paral putative membrane component' ecoli333 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'cynX' 'cyanate transport' ecoli1499 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ydeA' 'ABC superfamily (membrane)putative membrane component of ABC transport system appears to facilitate arabinose export contributes to control of arabinose regulon' ecoli3462 1,5,36 Cell processes Transport/binding proteins STP family 'yhjV' 'STP family of transport protein' ecoli47 1,5,9 Cell processes Transport/binding proteins CPA2 family 'kefC' 'CPA2 family k+ efflux antiporter glutathione-regulated (2nd module)' ecoli3409 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b3486' 'ABC superfamily (membrance) paral putative membrane component of transport system (3rd module)' ecoli2921 1,5,32 Cell processes Transport/binding proteins PiT family 'pitB' 'PiT family low-affinity phosphate transport(1st module)' ecoli3525 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'lldP' 'L-lactate permease(1st module)' ecoli581 1,5,31 Cell processes Transport/binding proteins POT family 'ybdA' 'paral putative POT family of transport protein (1st module)' ecoli769 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0793' 'putative membrane component of ABC transport system(2nd module)' ecoli3980 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yjcV' 'ABC superfamily (membrane) membrane component of allose ABC transport system(1st module)' ecoli1467 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yddA' 'ABC superfamily (atp_bind) paral putative ATP-binding module (2nd module)' ecoli252 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'ykfD' 'APC family of transport protein S-methylmethionine permease' ecoli3961 1,5,35 Cell processes Transport/binding proteins SSS family 'yjcG' 'SSS family transport protein' ecoli3643 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'bglF' 'Sugar Specific PTS family beta-glucosides enzyme II cryptic (2nd module eiia (ei interaction)?)' ecoli2324 1,5,21 Cell processes Transport/binding proteins MFS family 'emrY' 'MFS family of transport protein multidrug resistance protein y (2nd module)' ecoli662 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'nagE' 'Sugar Specific PTS family n-acetylglucosamine-specific enzyme IIABC (3rd module)' ecoli3587 1,5,21 Cell processes Transport/binding proteins MFS family 'uhpT' 'MFS family of transport protein hexose phosphate transport protein (2nd module)' ecoli3293 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'yhfM' 'APC family paral putative amino-acid transport protein (2nd module)' ecoli2655 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'ascF' 'PTS family enzyme II ABC (asc) cryptic transports specific beta-glucosides' ecoli4017 1,5,12 Cell processes Transport/binding proteins Dcu family 'dcuB' 'Dcu family anaerobic C4-dicarboxylate transporter' ecoli602 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'b0612' 'citrate carrier transport citrate trading for succinate export' ecoli3380 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'livH' 'ABC superfamily (membrane) membrane component of high-affinity branched-chain amino acid ABC transport system(2nd module)' ecoli2538 1,5,21 Cell processes Transport/binding proteins MFS family 'kgtP' 'MFS family of transport protein alpha-ketoglutarate permease(1st module)' ecoli3580 1,5,21 Cell processes Transport/binding proteins MFS family 'yicK' 'MFS family of transport protein two-module paral putative transport protein (2nd module)' ecoli2198 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'glpT' 'sn-glycerol-3-phosphate permease' ecoli566 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'pheP' 'phenylalanine-specific transport system' ecoli4041 1,5,34 Cell processes Transport/binding proteins SMR family 'sugE' 'SMR family of transport protein' ecoli3579 1,5,16 Cell processes Transport/binding proteins GPH family 'yicJ' 'GPH family paral putative transport protein' ecoli1827 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'yebI' 'inner memrane component of a high affininty Zn transport system' ecoli3043 1,5,36 Cell processes Transport/binding proteins STP family 'yhaO' 'STP family of transport protein (1st module)' ecoli1164 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b1191' 'PUTATIVE NA(+)/H(+) EXCHANGER according to SwissProt version 38 the orf starts at a methionine 42 aa upstream of b 1191 start' ecoli1514 1,5,21 Cell processes Transport/binding proteins MFS family 'b1543' 'MFS family of transport protein (1st module)' ecoli3188 1,5,35 Cell processes Transport/binding proteins SSS family 'panF' 'SSS family transport protein sodium/pantothenate symporter(1st module)' ecoli1633 1,5,20 Cell processes Transport/binding proteins MATE family 'ydhE' 'MATE family of transport protein(2nd module)' ecoli2357 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'xapB' 'xanthosine permease' ecoli1097 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'potC' 'ABC superfamily (membrane) membrane component of spermidine/putrescine ABC transport system(2nd module)' ecoli3604 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'glvC' 'PTS family arbutin-like IIC component' ecoli67 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yabK' 'ABC superfamily (membrane) membrane component of thiamine ABC transport system(1st module)' ecoli198 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yaeE' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli2497 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b2546' 'ABC superfamily (membrane)paral putative membrane component of ABC transport system (2nd module)' ecoli3594 1,5,21 Cell processes Transport/binding proteins MFS family 'emrD' 'MFS family of transport protein 2-module integral membrane pump; multidrug resistance (2nd module)' ecoli3836 - 3,2,8 Metabolism of small molecules Biosynthesis of cofactors, carriers Menaquinone, ubiquinone 'menA' '14-dihydroxy-2-naphthoate --> dimethylmenaquinone' ecoli45 1,5,21 Cell processes Transport/binding proteins MFS family 'yaaU' 'MFS family transport protein' ecoli4155 1,5,19 Cell processes Transport/binding proteins GntP family 'yjgT' 'GntP family l-idonate transporter (2nd module)' ecoli2137 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yejB' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli3026 1,5,21 Cell processes Transport/binding proteins MFS family 'exuT' 'MFS family of transport protein transport of hexuronates (2nd module)' ecoli1875 1,5,43 Cell processes Transport/binding proteins ArAAP family 'tyrP' 'ArAAP family tyrosine-specific transport system' ecoli328 1,5,25 Cell processes Transport/binding proteins NCS1 family 'codB' 'NCS1 family transport protein cytosine permease/transport(2nd module)' ecoli3971 1,5,10 Cell processes Transport/binding proteins DAACS family 'gltP' 'DAACS family of transport protein glutamate-aspartate symport protein' ecoli2141 1,5,21 Cell processes Transport/binding proteins MFS family 'bcr' 'MFS family of transport protein bicyclomycin resistance protein; transmembrane protein (2nd module)' ecoli2487 1,5,21 Cell processes Transport/binding proteins MFS family 'b2536' 'MFS family of transport protein (1st module)' ecoli3959 1,5,8 Cell processes Transport/binding proteins CPA1 family 'yjcE' 'CPA1 family PUTATIVE NA(+)/H(+) EXCHANGER YJCE(1st module)' ecoli807 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0831' 'paral putative membrane component of transport system' Test Accuracy: 62/64 (96.88%) Test Frequency class 'Transport/binding proteins': 151/712 (21.21%) Test Significance: dev(14.81) ; prob(2.207893E-39) Application to new data (2167 items): ecoli1604 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1634' 'orf' ecoli2823 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2887' 'putative oxidoreductase fe-s subunit (2nd module)' ecoli3170 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhcP' 'orf' ecoli487 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0496' 'putative oxidoreductase' ecoli821 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0845' 'paral putative transport protein (2nd module bind phosphorylated sugar? )' ecoli1349 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1378' 'paral putative oxidoreductase (2nd module)' ecoli3606 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yidE' 'paral putative transport protein(1st module)' ecoli1404 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1433' 'putative membrane transport protein' ecoli4009 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b4115' 'putative amino acid/amine transport protein cryptic' ecoli1575 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1605' 'putative arginine/ornithine antiporter' ecoli1562 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1592' 'orf' ecoli2419 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yffG' 'paral putative oxidoreductase (2nd module)' ecoli4034 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjeH' 'putative transport' ecoli3849 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yijE' 'orf (2nd module)' ecoli3780 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yihN' 'orf' ecoli2529 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfiK' 'paral putative transport protein' ecoli3419 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhiP' 'orf' ecoli2626 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2681' 'orf' ecoli3357 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3434' 'orf' ecoli2821 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2885' 'orf' ecoli1766 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1798' 'paral putative transport protein' ecoli3739 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yigM' 'paral putative transport protein (2nd module)' ecoli980 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1006' 'putative transport protein(2nd module)' ecoli2943 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yghB' 'orf' ecoli2997 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ygjE' 'paral putative DASS family of transport protein' ecoli3585 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yicO' 'orf (2nd module)' ecoli2585 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2639' 'putative pump protein' ecoli1658 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1690' 'paral putative MFS family of transport protein' ecoli4100 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ytfF' 'orf (1st module)' ecoli3114 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhbE' 'orf' ecoli1923 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yedA' 'orf (1st module)' ecoli2558 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2611' 'orf' ecoli1042 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'mviN' 'putative virulence factor' ecoli1504 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ydeD' 'orf' ecoli4221 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjiJ' 'paral putative transport protein (2nd module)' ecoli2250 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2292' 'putative transport protein' ecoli3600 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yidK' 'putative cotransporter' ecoli3731 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'rarD' 'chloramphenicol resistance' ecoli1505 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ydeF' 'paral putative transport protein (1st module)' ecoli502 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0511' 'orf' ecoli1743 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1775' 'paral putative transport protein (1st module)' ecoli3706 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yifJ' 'putative cytochrome' ecoli3083 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yraQ' 'orf' ecoli2715 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2775' 'orf' ecoli3322 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yrfG' 'orf' ecoli2858 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yggA' 'orf' ecoli4083 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjfS' 'orf' ecoli789 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ybiF' 'orf' ecoli2305 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfdC' 'putative transport' ecoli3576 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yicE' 'putative transport protein' ecoli2346 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2389' 'orf' ecoli2204 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2246' 'putative transport protein' ecoli3126 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yrbG' 'orf' ecoli320 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0328' 'paral putative transport protein' ecoli2285 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfcA' 'putative structural protein' ecoli1486 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1515' 'paral putative membrane component of ABC transport system' ecoli1444 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yddG' 'orf' ecoli7 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yaaJ' 'putative inner membrane transport protein' ecoli504 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0513' 'putative transport(2nd module)' ecoli4243 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjiY' 'putative carbon starvation protein' ecoli2769 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2832' 'putative transport protein' ecoli1943 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1981' 'shikimate and dehydroshikimate permease (2nd module)' ecoli1697 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1729' 'part of a kinase(1st module paral putative tdomain shared with transporter)' ecoli2322 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'dsdX' 'transport system permease (serine?)' ecoli2275 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'dedA' 'orf' ecoli873 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ycaD' 'paral putative transport protein (1st module)' ecoli4245 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b4356' 'paral putative transport protein cryptic orf joins former yjiZ and yjjL' ecoli1038 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1065' 'orf' ecoli2361 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfeH' 'putative cytochrome oxidase' ecoli1759 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1791' 'putative amino acid/amine transport protein (3rd module)' ecoli4049 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjeM' 'paral putative amino-acid transport protein' ecoli262 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yagG' 'paral putative transport protein' ecoli2729 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2789' 'paral putative membrane component of transport system (2nd module)' ecoli2256 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2298' 'putative S-transferase' ecoli794 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0818' 'orf' ecoli2906 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2972' 'paral putative peptidase' ecoli3958 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjcD' 'orf (2nd module)' Frequency rule on new data: 77/2167 (3.55%) Evaluation on training data (939 items): ecoli4029 - 3,3,19 Metabolism of small molecules Central intermediary metabolism Sulfur metabolism 'dsbD' 'thiol:disulfide interchange protein N-term.(1st module)' ecoli4024 1,5,31 Cell processes Transport/binding proteins POT family 'b4130' 'POT family of transport protein paral putative transport protein (3rd module)' ecoli2057 1,5,21 Cell processes Transport/binding proteins MFS family 'b2098' 'MFS family of transport protein (2nd module)' ecoli3359 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'gntU_1' 'split gene low-affinity gluconate transport permease protein in GNT-I system first part of fragment 1(1st module)' ecoli3425 1,5,4 Cell processes Transport/binding proteins Ars family 'arsB' 'Ars family arsenical pump membrane protein(2nd module)' ecoli1263 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'sapC' 'ABC superfamily (membrane) membrane component of peptide ABC transport system(2nd module)' ecoli1723 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1755' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli153 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'fhuB' 'ABC superfamily (membrane) split gene C-term module hydroxamate-dependent iron uptake (2nd module iron uptake )' ecoli1659 1,5,21 Cell processes Transport/binding proteins MFS family 'b1691' 'MFS family of transport protein' ecoli3396 1,5,21 Cell processes Transport/binding proteins MFS family 'yhhS' 'MFS family of transport protein (2nd module)' ecoli1566 1,5,21 Cell processes Transport/binding proteins MFS family 'b1596' 'MFS familty transport protein (2nd module)' ecoli3154 1,5,21 Cell processes Transport/binding proteins MFS family 'nanT' 'MFS family of transport protein sialic acid transporter cryptic in K12?(1st module)' ecoli2736 1,5,36 Cell processes Transport/binding proteins STP family 'sdaC' 'STP family of transport protein serine transporter' ecoli3783 1,5,16 Cell processes Transport/binding proteins GPH family 'yihP' 'GPH family paral putative transport protein' ecoli2680 1,5,19 Cell processes Transport/binding proteins GntP family 'b2740' 'GntP family of transport protein function unknown (3rd module)' ecoli3782 1,5,16 Cell processes Transport/binding proteins GPH family 'b3876' 'GPH family paral putative transport protein (2nd module)' ecoli1267 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b1296' 'APC family paral putative amino-acid transport protein' ecoli2631 1,5,21 Cell processes Transport/binding proteins MFS family 'emrB' 'MFS family of transport protein multidrug resistance; probably membrane translocase(1st module)' ecoli3049 1,5,36 Cell processes Transport/binding proteins STP family 'tdcC' 'STP family of transport protein anaerobically inducible L-threonine/ L-serine permease' ecoli1264 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'sapB' 'ABC superfamily (membrane) membrane component of peptide ABC transport system' ecoli1026 1,5,21 Cell processes Transport/binding proteins MFS family 'yceE' 'MFS family of transport protein (2nd module)' ecoli1586 1,5,16 Cell processes Transport/binding proteins GPH family 'uidB' 'GPH family glucuronide permease' ecoli425 1,5,21 Cell processes Transport/binding proteins MFS family 'ampG' 'MFS family of transport protein ampicillin resistance (1st module)' ecoli2115 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'lysP' 'APC family lysine-specific permease (2nd module)' ecoli4226 1,5,21 Cell processes Transport/binding proteins MFS family 'yjiO' 'MFS family of transport protein (1st module)' ecoli1179 1,5,38 Cell processes Transport/binding proteins SulP family 'ychM' 'SulP family transport protein (1st module)' ecoli2036 1,5,21 Cell processes Transport/binding proteins MFS family 'b2077' 'MFS family of transport protein (1st module)' ecoli675 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'potE' 'APC family putrescine-lyase antiporter' ecoli2608 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'gabP' 'transport permease protein of gamma-aminobutyrate' ecoli3157 1,5,13 Cell processes Transport/binding proteins DcuC 'yhcL' 'DcuC family of transport protein (2nd module)' ecoli1159 1,5,27 Cell processes Transport/binding proteins NhaA family 'nhaB' 'NhaB family of transport protein Na+/H+ antiporter regulator of intracellular pH(1st module)' ecoli3675 1,5,21 Cell processes Transport/binding proteins MFS family 'yieO' 'MFS family of tranport protein (1st mdule)' ecoli3466 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'dppB' 'ABC superfamily (membrane) membrane component of dipeptide ABC transport system; permease protein 1(2nd module)' ecoli3671 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'rbsC' 'ABC superfamily (membrane) ABC superfamily of transport protein D-ribose high-affinity ABC transport system(1st module ATP-binding subunit)' ecoli1705 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'celB' 'PTS family sugar specific enzyme II for cellobiose arbutin and salicin' ecoli345 1,5,21 Cell processes Transport/binding proteins MFS family 'b0353' 'MFS family transport protein (2nd module function unknown)' ecoli394 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b0402' 'APC family of transport protein proline permease transport protein' ecoli3059 1,5,21 Cell processes Transport/binding proteins MFS family 'yhaU' 'MFS family of transport protein (D)-glucarate or galactarate transporter (1st module)' ecoli2129 1,5,21 Cell processes Transport/binding proteins MFS family 'yeiO' 'MFS family proton-coupled sugar efflux pump transport selective monosaccharides and disaccharides narrower substr. specificity than SetA(2nd module)' ecoli4026 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'cadB' 'APC family transport of lysine/cadaverine(1st module)' ecoli2448 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'uraA' 'uracil transport' ecoli2899 1,5,21 Cell processes Transport/binding proteins MFS family 'nupG' 'MFS family of transport protein transport of nucleosides (2nd module)' ecoli3273 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'kefB' 'K+ efflux; NEM-activable K+/H+ antiporter' ecoli3379 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'livM' 'ABC superfamily (membrane) membrane component of high-affinity branched-chain amino acid ABC transport system (2nd module)' ecoli3022 1,5,10 Cell processes Transport/binding proteins DAACS family 'ygjU' 'DAACS family Na+/serine (threonine) symporter' ecoli3011 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'ygjI' 'APC family paral putative amino-acid transport protein' ecoli2035 1,5,33 Cell processes Transport/binding proteins RNDfamily 'b2076' 'RND family of transport protein paral putative outer membrane receptor' ecoli3630 1,5,43 Cell processes Transport/binding proteins ArAAP family 'tnaB' 'ArAAP family low affinity tryptophan permease' ecoli3668 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'kup' 'low affinity potassium transport system' ecoli4121 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yjfF' 'ABC superfamily (membrane) ABC superfamily of transport protein (1st module membrance component)' ecoli393 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'brnQ' 'branched chain; mutants valine and o-methylthreonine resistant glyclyvaline sensitive; transport system I for Ile Leu and Val' ecoli833 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'potI' 'ABC superfamily (membrane) membrane component of putrescine ABC transport system(2nd module)' ecoli1570 1,5,34 Cell processes Transport/binding proteins SMR family 'b1600' 'SMR family of transport protein' ecoli1414 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1443' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli388 1,5,21 Cell processes Transport/binding proteins MFS family 'araJ' 'MFS family of transport protein involved in either transport or processing of arabinose polymers (2nd module function unknown)' ecoli1098 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'potB' 'ABC superfamily (membrane) membrane component of spermidine/putrescine ABC transport system(2nd module)' ecoli4178 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'fecC' 'ABC superfamily (membrane) citrate-dependent iron(III) transport protein (2nd module)' ecoli1463 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'xasA' 'APC family acid sensitivity protein putative glutamate:gamma-aminobutyric acid antiporter (GadC)(2nd module)' ecoli2343 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'b2386' 'Sugar Specific paral putative membrane component of transport system' ecoli2138 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yejE' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli469 1,5,9 Cell processes Transport/binding proteins CPA2 family 'ybaL' 'CPA2 family transport protein' ecoli3287 1,5,21 Cell processes Transport/binding proteins MFS family 'yhfC' 'MFS family of transport protein paral putative transport protein' ecoli2375 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'cysU' 'ABC superfamily (membrane) membrane component of sulfate thiosulfate ABC transport system (2nd module)' ecoli874 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b0899' 'APC family paral putative amino-acid transport protein' ecoli40 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'caiT' 'probable carnitine transporter' ecoli2878 1,5,21 Cell processes Transport/binding proteins MFS family 'galP' 'MFS family of transport protein galactose-proton symport of transport system (2nd module)' ecoli2005 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'b2046' 'probable export protein /export to periplasm in colanic acid gene cluster' ecoli2741 1,5,21 Cell processes Transport/binding proteins MFS family 'fucP' 'MFS family of transport protein fucose permease(1st module)' ecoli3711 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'yifK' 'APC family paral putative amino-acid transport protein' ecoli1283 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1312' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli2181 - 3,4,4 Metabolism of small molecules Degradation of small molecules Fatty acids 'atoB' 'short chain fatty acids transporter' ecoli3934 - 3,2,8 Metabolism of small molecules Biosynthesis of cofactors, carriers Menaquinone, ubiquinone 'ubiA' 'p-hydroxybenzoate: octaprenyltransferase(1st module)' ecoli3469 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'yhjX' 'putative resistance protein' ecoli19 1,5,27 Cell processes Transport/binding proteins NhaA family 'nhaA' 'NhaA family of transport protein Na+/H antiporter pH dependent(1st module)' ecoli3583 1,5,21 Cell processes Transport/binding proteins MFS family 'yicM' 'MFS family of tranport protein (1st mdule)' ecoli3855 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'frwC' 'PTS system fructose-like IIC component first module overlaps second(2nd module)' ecoli1215 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'oppB' 'ABC superfamily (membrane) membrane component of oligopeptide ABC transport system(2nd module)' ecoli1440 1,5,21 Cell processes Transport/binding proteins MFS family 'narU' 'MFS family of transport protein nitrate sensor-transmitter protein anaerobic respiratory path(1st module)' ecoli2107 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'mglC' 'ABC superfamily (membrane) membrane component of methyl-galactoside ABC transport system and galactose taxis(1st module)' ecoli1679 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'btuC' 'ABC superfamily (membrane) membrane component of vitamin B12 ABC transport system' ecoli440 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'mdlA' 'ATP-binding component of a transport system (2nd module)' ecoli477 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'b0486' 'APC family of transport protein amino-acid transport protein' ecoli851 1,5,22 Cell processes Transport/binding proteins MIP family 'aqpZ' 'MIP family transmembrane water channel; aquaporin Z' ecoli4185 1,5,19 Cell processes Transport/binding proteins GntP family 'yjhF' 'GntP family of transport protein (1st module)' ecoli359 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0367' 'ABC superfamily (membrane) membrane component of taurine ABC transport system' Training Accuracy: 79/85 (92.94%) Training Frequency class 'Transport/binding proteins': 187/939 (19.91%) Training Significance: dev(16.86) ; prob(5.072241E-48) Evaluation on validation data (471 items): ecoli4014 1,5,16 Cell processes Transport/binding proteins GPH family 'melB' 'GPH family melibiose permease II' ecoli2868 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'cmtA' 'PTS family mannitol-specific enzyme II component cryptic' ecoli837 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'artM' 'arginine 3rd transport system permease protein' ecoli1883 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yecC' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli3521 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'mtlA' 'Sugar Specific PTS family mannitol-specific enzyme IIABC components (3rd module eii a domain phosphoryl by p-hpr 491-637)' ecoli419 1,5,21 Cell processes Transport/binding proteins MFS family 'b0427' 'MFS family transport protein' ecoli1216 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'oppC' 'ABC superfamily (membrane)homolog of Salmonella oligopeptide transport permease protein(2nd module)' ecoli3416 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'pitA' 'low-affinity phosphate transport' ecoli3926 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'malG' 'ABC superfamily (membrane) membrane component of maltose ABC transport system (2nd module)' ecoli3375 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ugpA' 'ABC superfamily (membrane) sn-glycerol 3-phosphate integral membrane protein ABC transport system' ecoli2778 1,5,21 Cell processes Transport/binding proteins MFS family 'araE' 'MFS family of transport protein low-affinity L-arabinose transport system proton symport protein(1st module)' ecoli4098 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'cycA' 'APC family transport of D-alanine D-serine and glycine (2nd module)' ecoli2623 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'proW' 'ABC superfamily (membrane) membrane component of high-affinity ABC transport system for glycine betaine and proline (2nd module)' ecoli1196 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'narK' 'nitrite extrusion protein(2nd module)' ecoli2089 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yehY' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli1627 1,5,21 Cell processes Transport/binding proteins MFS family 'b1657' 'MFS family of transport protein (2nd module)' ecoli2772 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'ygeD' 'putative resistance proteins' ecoli3196 1,5,33 Cell processes Transport/binding proteins RNDfamily 'acrF' 'RND family of transport protein acriflavin resistance protein F multidrug efflux (?encodes lipoprotein with signal peptide; osmotcially remedial envelope defect)' ecoli1630 1,5,21 Cell processes Transport/binding proteins MFS family 'ydhC' 'MFS family transport protein (2nd module)' ecoli70 1,5,21 Cell processes Transport/binding proteins MFS family 'yabM' 'MFS family of transport protein proton-coupled beta-galactosidase/sugar efflux pump ? role in lactose metabolism (2nd module)' ecoli4130 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'treB' 'PTS family enzyme II trehalose specific (maltose may be transported)' ecoli2158 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'ccmB' 'heme exporter protein B cytochrome c-type biogenesis protein' ecoli4168 1,5,21 Cell processes Transport/binding proteins MFS family 'yjhB' 'MFS family of tranport protein (1st module)' ecoli1973 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'yeeF' 'APC family paral putative amino-acid transport protein' ecoli3938 1,5,20 Cell processes Transport/binding proteins MATE family 'dinF' 'MATE family of transport protein; also DNA-damage-inducible protein F;induced by UV and mitomycin C; SOS lexA regulon(2nd module)' ecoli1282 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1311' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli1796 1,5,21 Cell processes Transport/binding proteins MFS family 'b1828' 'MFS family of transport protein (2nd module)' ecoli1424 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b1453' 'L-asparagine permease (2nd module)' ecoli3659 1,5,24 Cell processes Transport/binding proteins Membrane-bound ATP synthase 'atpB' 'membrane-bound ATP synthase F0 sector subunit a' ecoli3490 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'xylH' 'ABC superfamily (membrane)d-xylose transport permease (2nd module might interact with atp hydrolysing subunit )' ecoli3465 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'dppC' 'ABC superfamily (membrane) membrane component of dipeptide ABC transport system; permease protein 2 (2nd module)' ecoli2782 1,5,36 Cell processes Transport/binding proteins STP family 'b2845' 'STP family of transport protein' ecoli3223 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'prlA' 'protein secretion inner membrane preprotein translocase SecY subunit interacts with SecE (1st module)' ecoli3925 1,5,21 Cell processes Transport/binding proteins MFS family 'xylE' 'MFS family of tranport protein xylose-proton symport (2nd module)' ecoli3612 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'yidT' 'D-galactonate transport' ecoli2909 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b2975' 'LctP transporter L-lactate permease homologue' ecoli3588 1,5,21 Cell processes Transport/binding proteins MFS family 'uhpC' 'regulator of uhpT (1st module)' ecoli1867 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'b1899' 'split high-affinity L-arabinose transport system; membrane protein fragment 1' ecoli1996 - 4,1,4 Structural elements Cell envelop Surface polysaccharides & antigens 'rfbX' 'hydroponic protein o-antigen (3rd module)' ecoli4005 1,5,21 Cell processes Transport/binding proteins MFS family 'proP' 'MFS family of tranport protein low-affinity constitutive transport system; proline permease II transports proline and betaine under conditions of hyperosmolarity(2nd module)' ecoli1591 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'malX' 'Sugar Specific PTS family maltose and glucose-specific ii abc (2nd module hydrophilic second phosphorylation domain)' ecoli3631 1,5,21 Cell processes Transport/binding proteins MFS family 'yidY' 'MFS family of tranport protein (1st mdule)' ecoli1877 - 2,2,7 Macromolecule metabolism Macromolecule synthesis, modification Phospholipids 'pgsA' 'phosphatidylglycerophosphate synthetase = CDP-12-diacyl-sn-glycero-3-phosphate phosphatidyl transferase' ecoli3093 1,5,43 Cell processes Transport/binding proteins ArAAP family 'mtr' 'ArAAP family tryptophan-specific transport protein' ecoli2280 1,5,21 Cell processes Transport/binding proteins MFS family 'b2322' 'MFS family of transport protein paral putative (2nd module)' ecoli2380 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'b2429' 'Sugar Specific paral putative PTS system enzyme II' ecoli4031 1,5,12 Cell processes Transport/binding proteins Dcu family 'dcuA' 'Dcu family anaerobic dicarboxylate transport' ecoli2818 1,5,13 Cell processes Transport/binding proteins DcuC 'b2882' 'DcuC family paral putative transport protein' ecoli1189 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'chaA' 'sodium-calcium/proton antiporter' ecoli692 1,5,31 Cell processes Transport/binding proteins POT family 'b0709' 'POT family of transport protein (1st module)' ecoli3451 1,5,10 Cell processes Transport/binding proteins DAACS family 'dctA' 'DAACS family of transport protein uptake of C4-dicarboxylic acids' ecoli2824 1,5,26 Cell processes Transport/binding proteins NCS2 family 'b2888' 'NCS2 family paral putative transport protein' ecoli909 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0934' 'ABC superfamily (membrane) probable membrane component of transport system' ecoli1737 1,5,21 Cell processes Transport/binding proteins MFS family 'ydjE' 'MFS family of transport protein (1st module)' Validation Accuracy: 49/54 (90.74%) Validation Frequency class 'Transport/binding proteins': 104/471 (22.08%) Validation Significance: dev(12.16) ; prob(6.529304E-27) ------------------ Rule 48: (33, lift 4.9) amino_acid_pairs_ef <= 1 [hom( A ),classification( A ,rhizobium)] = 1 [hom( A ),e_val_lteq( A ,0.0006),species( A ,oenothera_bertiana__bertero_s_evening_primrose_)] = 0 [hom( A ),species( A ,mycoplasma_hyorhinis),mol_wt_lteq( A ,77359)] = 1 -> class 'Transport/binding proteins' [0.971] Evaluation on test data (712 items): ecoli3646 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'pstB' 'ABC superfamily (atp_bind) ATP-binding component of high-affinity phosphate-specific ABC transport system' ecoli924 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0949' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli151 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'fhuC' 'ABC superfamily (atp_bind) ATP-binding component of hydroxymate-dependent iron transport' ecoli3927 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'malF' 'ABC superfamily (membrane) membrane component of maltose ABC transport system (2nd module)' ecoli889 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'msbA' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli2374 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'cysW' 'ABC superfamily (membrane) membrane component of sulfate ABC transport system; permease W protein' ecoli3275 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yheS' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli805 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0829' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli808 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0832' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli581 1,5,31 Cell processes Transport/binding proteins POT family 'ybdA' 'paral putative POT family of transport protein (1st module)' ecoli4176 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'fecE' 'ABC superfamily (atp_bind) ATP-binding component of citrate-dependent iron(III) transport protein' ecoli3200 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yhdY' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli2622 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'proV' 'ABC superfamily (atp_bind) ATP-binding component of transport system for glycine betaine and proline(1st module)' ecoli3125 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b3195' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli662 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'nagE' 'Sugar Specific PTS family n-acetylglucosamine-specific enzyme IIABC (3rd module)' ecoli644 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'gltJ' 'ABC superfamily (membrane) glutamate/aspartate transport system permease' ecoli3998 1,5,29 Cell processes Transport/binding proteins Outer membrane channel 'phnE' 'membrane channel protein component of Pn transporter' ecoli602 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'b0612' 'citrate carrier transport citrate trading for succinate export' ecoli486 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ybbA' 'ABC superfamily (atp_bind) putative' ecoli566 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'pheP' 'phenylalanine-specific transport system' ecoli1249 - 2,2,7 Macromolecule metabolism Macromolecule synthesis, modification Phospholipids 'pgpB' 'non-essential phosphatidylglycerophosphate phosphatase membrane bound' ecoli3201 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yhdZ' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli1020 - 1,6,2 Cell processes Adaptation Osmotic adaptation 'b1047' 'membrane protein required for succinyl substitution of glucan backbone of OPG (osmoregulated periplasmic glucan) possible succinyl transferase' ecoli2264 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'hisP' 'ABC superfamily (atp_bind) ATP-binding component of histidine ABC transport system' ecoli578 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'fepC' 'ABC superfamily (atp_bind) ATP-binding component of ferric enterobactin transport(2nd module)' ecoli1261 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'sapF' 'ABC superfamily (atp_bind) ATP-binding protein of peptide ABC transport system(2nd module)' ecoli358 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0366' 'ABC superfamily (atp_bind) ATP-binding component of a taurine transport system' ecoli2266 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'hisQ' 'ABC superfamily (membrane)histidine transport system' ecoli3825 - 3,5,5 Metabolism of small molecules Energy metabolism, carbon Glycolysis 'tpiA' 'triosephosphate isomerase' ecoli3981 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yjcW' 'ABC superfamily (atp_bind) ATP-binding component of allose transport system (2nd module)' ecoli3142 - 3,3,15 Metabolism of small molecules Central intermediary metabolism Pool, multipurpose conversions of intermed. met'm 'gltB' 'glutamate synthase large subunit' ecoli2682 - 2,2,6 Macromolecule metabolism Macromolecule synthesis, modification Lipoprotein 'nlpD' 'lipoprotein(2nd module)' ecoli1826 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1858' 'ABC superfamily (atp_bind) ATP-binding component of a high affinity Zn transport system(1st module)' ecoli840 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'artP' 'ABC superfamily (atp&memb) ATP-binding component of 3rd arginine transport system(2nd module)' ecoli2373 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'cysA' 'ABC superfamily (atp_bind) ATP-binding component of sulfate permease A protein of ABC transport; chromate resistance (1st module)' ecoli790 - 4,1,3 Structural elements Cell envelop Outer membrane constituents 'ompX' 'outer membrane protease receptor for phage OX2' ecoli3131 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yhbG' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli127 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yadG' 'ABC superfamily (atp_bind) ATP-binding component of transport protein (1st module)' ecoli1455 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1484' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli254 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yagC' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' Test Accuracy: 33/40 (82.50%) Test Frequency class 'Transport/binding proteins': 151/712 (21.21%) Test Significance: dev(9.48) ; prob(2.212194E-16) Application to new data (2167 items): ecoli3004 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3071' 'orf' ecoli3248 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yheF' 'orf (2nd module)' ecoli3474 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yiaD' 'paral putative membrance protein (2nd module)' ecoli2715 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2775' 'orf' ecoli1611 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1641' 'orf' ecoli2088 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yehX' 'paral putative ATP-binding component of transport system' ecoli2578 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2632' '2nd module of a paral GTP-binding factor (2nd module)' ecoli103 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yacE' 'putative DNA repair protein' ecoli999 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1025' 'orf(2nd module) homologue of Yersinia pestis hmsT involved in haemin uptake/storage ?cryptic' ecoli1484 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1513' 'paral putative ATP-binding component of transport system (2nd module)' ecoli2087 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yehW' 'paral putative membrane component of transport system' ecoli3453 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yhjL' 'paral putative reductase' ecoli2863 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yggC' 'paral putative kinase' ecoli2498 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2547' 'paral putative ATP-binding component of transport system' ecoli1454 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1483' 'paral putative ATP-binding component of transport system' ecoli2308 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2351' 'orf' ecoli255 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0263' 'paral putative membrane component of transport system' ecoli1442 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1471' 'putative glycoportein' ecoli2212 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2254' 'orf(1st module)' Frequency rule on new data: 19/2167 (0.88%) Evaluation on training data (939 items): ecoli855 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0879' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli740 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'modB' 'ABC superfamily (membrane) membrane component of molybdate ABC transport system (2nd module)' ecoli3489 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'xylG' 'ABC superfamily (atp_bind) ATP-binding component of D-xylose ABC transport system(2nd module)' ecoli1456 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1485' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli2265 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'hisM' 'ABC superfamily (membrane)histidine transport membrane protein m (2nd module transport function )' ecoli3991 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'phnK' 'ABC superfamily (atp_bind) ATP-binding component of phosphonate ABC transportbelieved to be part of carbon-phosphorus (C-P) lyase in phosphonate metabolism' ecoli3386 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ftsE' 'ABC superfamily (atp_bind) ATP-binding component of a membrane-associated complex involved in cell division' ecoli66 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yabJ' 'ABC superfamily (atp_bind) ATP-binding component of thiamine ABC transport system' ecoli3403 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'nikE' 'ABC superfamily (stp_bind) ATP-binding component of nickel ABC transport system probably couples energy to transport system' ecoli1650 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1682' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli3373 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ugpC' 'ABC superfamily (atp_bind) ATP-binding component of sn-glycerol 3-phosphate ABC transport system (1st module)' ecoli1091 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1118' 'ABC superfamily (membrane) paral putative membrane component of ABC transport system' ecoli1090 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1117' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli675 1,5,42 Cell processes Transport/binding proteins APC family of transport protein 'potE' 'APC family putrescine-lyase antiporter' ecoli1348 1,5,29 Cell processes Transport/binding proteins Outer membrane channel 'b1377' 'outer membrane protein n non-specific porin (2nd module)' ecoli643 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'gltK' 'ABC superfamily (membrane) glutamate/aspartate transport (1st module)' ecoli3199 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yhdX' 'ABC superfamily (membrane)paral putative membrane component of transport system' ecoli908 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ycbE' 'paral putative ATP-binding component of transport system' ecoli1262 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'sapD' 'ABC superfamily (atp_bind) ATP-binding protein of peptide transport system(2nd module) affects potassium transport;' ecoli3463 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'dppF' 'ABC superfamily (atp_bind) ATP-binding component of a dipeptide transport system(1st module)' ecoli2139 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'yejF' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli861 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'cydC' 'ABC superfamily (atp&memb) ATP-binding and membrane components of cytochrome-related ABC transport(2nd module)' ecoli3378 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'livG' 'ABC superfamily (atp_bind) ATP-binding component of high-affinity branched-chain amino acid ABC transport system' ecoli3648 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'pstC' 'ABC superfamily (membrane) membrane component of high-affinity phosphate-specific ABC transport system (2nd module)' ecoli1218 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'oppF' 'ABC superfamily (atp_bind) ATP-binding protein of oligopeptide ABC transport system' ecoli3401 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'nikC' 'ABC superfamily (membrane) membrane component in nickel transport system probably forms heterodimeric pore with NikB(1st module)' ecoli2159 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ccmA' 'ABC superfamily (atp_bind) ATP-binding component of heme exporter A heme exporter protein A cytochrome c-type biogenesis protein' ecoli2108 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'mglA' 'ABC superfamily (atp_bind) ATP-binding component of methyl-galactoside transport and galactose taxis (2nd module)' ecoli3402 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'nikD' 'ABC superfamily (atp_bind) ATP-binding component of nickel ABC transport system probably couples energy to transport system(2nd module)' ecoli1882 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1917' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli481 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b0490' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli440 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'mdlA' 'ATP-binding component of a transport system (2nd module)' ecoli359 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b0367' 'ABC superfamily (membrane) membrane component of taurine ABC transport system' Training Accuracy: 33/33 (100.00%) Training Frequency class 'Transport/binding proteins': 187/939 (19.91%) Training Significance: dev(11.52) ; prob(7.461196E-24) Evaluation on validation data (471 items): ecoli3929 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'malK' 'ABC superfamily (atp_bind) ATP-binding component of transport system for maltose phenotypic repressor of mal operon(1st module)' ecoli441 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'mdlB' 'ABC superfamily (atp&memb) paral putative ATP-binding component of transport system' ecoli4119 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'ytfS' 'ABC superfamily (atp_bind) putative ATP-binding component of a transport system' ecoli3990 - 3,3,13 Metabolism of small molecules Central intermediary metabolism Phosphorus compounds 'phnL' 'ABC superfamily (atp_bind) ATP-binding component of phosphonate ABC transport believed to be part of carbon-phosphorus (C-P) lyase in phosphonate metabolism' ecoli4168 1,5,21 Cell processes Transport/binding proteins MFS family 'yjhB' 'MFS family of tranport protein (1st module)' ecoli838 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'artQ' 'ABC superfamily (membrane) membrane component of 3rd arginine ABC transport system' ecoli642 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'gltL' 'ABC superfamily (atp_bind) ATP-binding protein of glutamate/aspartate transport system' ecoli3377 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'livF' 'ABC superfamily (atp_bind) ATP-binding component of leucine ABC transport system' ecoli1677 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'btuD' 'ABC superfamily (atp_bind) ATP-binding component of vitamin B12 ABC transport system(2nd module)' ecoli932 - 4,1,3 Structural elements Cell envelop Outer membrane constituents 'ompA' 'outer membrane protein 3a (II*;G;d)(2nd module)' ecoli199 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'abc' 'ABC superfamily (atp_bind) ATP-binding component of ABC transport system(1st module)' ecoli1868 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'araG' 'ABC superfamily (atp_bind) ATP-binding component of high-affinity l-arabinose transport system (2nd module)' ecoli741 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'modC' 'ABC superfamily (atp_bind) ATP-binding component of molybdate ABC transport (1st module)' ecoli1724 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'b1756' 'ABC superfamily (atp_bind) paral putative ATP-binding component of transport system' ecoli4000 1,5,1 Cell processes Transport/binding proteins ABC superfamily (atp_bind) 'phnC' 'ABC superfamily (atp_bind) ATP-binding component of phosphonate ABC transport system' ecoli714 - 2,2,9 Macromolecule metabolism Macromolecule synthesis, modification Protein modufication 'hrsA' 'protein modification enzyme induction of ompc (2nd module eiibc? )' ecoli692 1,5,31 Cell processes Transport/binding proteins POT family 'b0709' 'POT family of transport protein (1st module)' ecoli1737 1,5,21 Cell processes Transport/binding proteins MFS family 'ydjE' 'MFS family of transport protein (1st module)' Validation Accuracy: 15/18 (83.33%) Validation Frequency class 'Transport/binding proteins': 104/471 (22.08%) Validation Significance: dev(6.27) ; prob(5.582286E-08) ------------------ Rule 31: (10/1, lift 19.6) amino_acid_pair_ratio_qh > 8.5 amino_acid_pairs_ah > 0 amino_acid_pairs_dy <= 0 [hom( A ),keyword( A ,transmembrane),classification( A ,kinetoplastida)] = 0 -> class 'Laterally acquirred elements' [0.833] Evaluation on test data (712 items): ecoli1989 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_7' 'IS5 protein' ecoli266 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insB_3' 'IS1 protein InsB' ecoli3116 - 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplU' '50S ribosomal subunit protein L21' ecoli1580 - 2,2,3 Macromolecule metabolism Macromolecule synthesis, modification DNA - replication, repair, restraction/modification 'tus' 'DNA-binding protein; inhibition of replication at Ter sites' ecoli1953 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_6' 'IS5 protein' Test Accuracy: 3/5 (60.00%) Test Frequency class 'Laterally acquirred elements': 25/712 (3.51%) Test Significance: dev(6.86) ; prob(4.104129E-04) Application to new data (2167 items): ecoli4004 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjcZ' 'orf' ecoli1872 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1904' 'orf' ecoli3110 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhbY' 'orf' ecoli1926 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yedJ' 'orf' ecoli1266 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1295' 'orf' ecoli2963 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ygiN' 'orf' ecoli240 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yafX' 'orf' ecoli2609 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ygaE' 'paral putative regulator protein' ecoli4095 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ytfA' 'orf' Frequency rule on new data: 9/2167 (0.42%) Evaluation on training data (939 items): ecoli3683 - 3,1,21 Metabolism of small molecules Amino acid biosynthesis Valine 'ilvM' 'acetolactate synthase II small subunit' ecoli251 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_1' 'IS5 protein 1' ecoli3428 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_11' 'IS5 protein 11' ecoli2150 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_8' 'IS5 protein' ecoli542 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_2' 'IS 5 protein' ecoli646 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_3' 'IS5 protein' ecoli3368 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insB_6' 'IS1 protein InsB' ecoli1861 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insB_5' 'IS1 protein InsB' ecoli21 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insB_1' 'IS1 protein InsB' ecoli2916 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_9' 'IS5 protein' Training Accuracy: 9/10 (90.00%) Training Frequency class 'Laterally acquirred elements': 40/939 (4.26%) Training Significance: dev(13.43) ; prob(4.441930E-12) Evaluation on validation data (471 items): ecoli1302 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_4' 'IS5 protein' ecoli2041 5,1,2 Extrachromosomal Laterally acquirred elements Phage-related functions and prophages 'ogrK' 'prophage P2 ogr protein' ecoli962 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insB_4' 'IS1 protein InsB' ecoli2430 - 3,3,15 Metabolism of small molecules Central intermediary metabolism Pool, multipurpose conversions of intermed. met'm 'gcvR' 'transcriptional regulation of gcv operon' ecoli256 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'insB_2' 'IS1 protein InsB 2' ecoli1199 - 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'narJ' 'nitrate reductase 1 delta subunit assembly function' ecoli3148 5,1,4 Extrachromosomal Laterally acquirred elements Transposon-related functions 'yi52_10' 'IS5 protein 10' Validation Accuracy: 5/7 (71.43%) Validation Frequency class 'Laterally acquirred elements': 26/471 (5.52%) Validation Significance: dev(7.64) ; prob(9.608591E-06) ------------------ Rule 20: (10, lift 9.7) amino_acid_pairs_ir > 0 [hom( A ),e_val_lteq( A ,3e-06),species( A ,corynebacterium_glutamicum)] = 0 [hom( A ),psi_iter_lteq( A ,13),species( A ,azorhizobium_caulinodans)] = 0 [hom( A ),psi_iter_lteq( A ,7),classification( A ,paracoccus)] = 1 [hom( A ),species( A ,mycoplasma_hyorhinis),mol_wt_lteq( A ,77359)] = 0 [hom( A ),species( A ,drosophila_melanogaster__fruit_fly_),keyword( A ,repeat)] = 0 -> class 'Energy metabolism carbon' [0.917] Evaluation on test data (712 items): ecoli1439 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'narZ' 'nitrate reductase 2 alpha subunit(1st module)' ecoli3967 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'nrfD' 'putative nitrate reductase formate dependent also paral putative STP family of transport protein' ecoli3798 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'fdoI' 'formate dehydrogenase cytochrome B556 (FDO) subunit' ecoli2928 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'hybC' 'probable large subunit hydrogenase-2 module (1st module)' ecoli2438 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'b2487' 'hydrogenase 4 subunit' ecoli1209 - 3,3,17 Metabolism of small molecules Central intermediary metabolism Salvage of nucleosides and nucleotides 'tdk' 'thymidine kinase' ecoli1089 - 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1116' 'ABC superfamily (membrane) paral putative membrane component of ABC transport system' ecoli1808 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'b1840' 'putative resistance protein' ecoli2246 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoA' 'NADH dehydrogenase I chain A' ecoli348 3,5,4 Metabolism of small molecules Energy metabolism, carbon Fermentation 'adhC' 'alcohol dehydrogenase class III EC 1.1.1.1(1st module)' ecoli2661 3,5,4 Metabolism of small molecules Energy metabolism, carbon Fermentation 'hycE' 'large subunit of hydrogenase 3 (part of FHL complex)' ecoli124 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'gcd' 'glucose dehydrogenase' ecoli1449 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'b1478' 'alcohol dehydrogenase propanol preferring EC 1.1.1.1(1st module)' ecoli580 - 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'fepD' 'ABC superfamily (membrane) membrane component of ferric enterobactin (enterochelin) ABC transport' ecoli3800 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'fdoG' 'formate dehydrogenase-O major subunit(1st module)' ecoli2220 - 3,2,8 Metabolism of small molecules Biosynthesis of cofactors, carriers Menaquinone, ubiquinone 'menB' 'dihydroxynaphtoic acid synthetase' ecoli2242 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoF' 'NADH dehydrogenase I chain F(1st module)' Test Accuracy: 11/17 (64.71%) Test Frequency class 'Energy metabolism carbon': 70/712 (9.83%) Test Significance: dev(7.60) ; prob(5.830867E-08) Application to new data (2167 items): ecoli1841 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1873' 'paral putative cytochrome c-type protein(1st module)' ecoli1557 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1587' 'paral putative reductase 2(1st module)' ecoli4056 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjeS' 'orf' ecoli3078 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yraL' 'orf' ecoli522 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0531' 'paral putative chaperone' ecoli3037 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhaI' 'orf' ecoli1472 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1501' '3rd module of a paral putative reductase (3rd module)' ecoli4058 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjeE' 'orf' ecoli1558 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1588' 'paral putative reductase 2(1st module)' ecoli1420 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1449' 'paral putative oxidoreductase' ecoli1718 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1750' 'orf' ecoli1744 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1776' 'paral putative oxidoreductase' ecoli3183 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yhdH' 'putative dehydrogenase(2nd module)' ecoli2305 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yfdC' 'putative transport' ecoli2752 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2812' 'paral putative enzyme biosynthesis' ecoli852 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0876' 'orf' ecoli1284 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1313' 'paral putative oxidoreductase' ecoli1345 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1374' 'putative transposon resolvase' ecoli317 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0325' 'paral putative oxidoreductase' Frequency rule on new data: 19/2167 (0.88%) Evaluation on training data (939 items): ecoli869 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'dmsA' 'anaerobic dimethyl sulfoxide reductase subunit A(1st module)' ecoli3945 3,5,3 Metabolism of small molecules Energy metabolism, carbon Electron transport 'qor' 'quinone oxidoreductase NADPH dependent(1st module)' ecoli2243 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoE' 'NADH dehydrogenase I chain E' ecoli2244 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'b2286' 'NADH dehydrogenase I chain C D' ecoli707 3,5,8 Metabolism of small molecules Energy metabolism, carbon TCA cycle 'sdhB' 'succinate dehydrogenase Fe-S protein EC 1.3.5.1' ecoli2659 3,5,4 Metabolism of small molecules Energy metabolism, carbon Fermentation 'hycG' 'hydrogenase activity(1st module)' ecoli947 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'hyaB' 'hydrogenase-1 large subunit' ecoli1197 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'narG' 'nitrate reductase 1 alpha subunit(1st module)' ecoli970 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'torC' 'trimethylamine N-oxide reductase cytochrome c-type subunit also has activity as negativer regulator of tor operon(1st module)' ecoli2161 3,5,3 Metabolism of small molecules Energy metabolism, carbon Electron transport 'napB' 'cytochrome C550 in periplasmic complex with NapA' Training Accuracy: 10/10 (100.00%) Training Frequency class 'Energy metabolism carbon': 89/939 (9.48%) Training Significance: dev(9.77) ; prob(5.851189E-11) Evaluation on validation data (471 items): ecoli1445 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'fdnG' 'formate dehydrogenase-N nitrate-inducible alpha subunit(1st module)' ecoli1365 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'b1394' 'phenylacetic acid degradation protein probable enoyl-CoA hydratase' ecoli2160 3,5,3 Metabolism of small molecules Energy metabolism, carbon Electron transport 'napC' 'cytochrome c-type protein' ecoli971 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'torA' 'trimethylamine N-oxide reductase subunit' ecoli948 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'hyaC' 'probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit' ecoli2440 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'b2489' 'hydrogenase 4 Fe-S subunit(1st module)' ecoli620 - 3,2,7 Metabolism of small molecules Biosynthesis of cofactors, carriers Lipoate 'lipB' 'protein of lipoate biosynthesis' ecoli3973 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'fdhF' 'selenopolypeptide subunit of formate dehydrogenase H (part of formate hydrogen-lyase complex: FHL complex) EC 1.2.1.2 CONSISTS OF TWO SEPARABLE ENZYMATIC ACTIVITIES: A FORMATE DEHYDROGENASE COMPONENT(1st module)' ecoli3875 - 3,2,2 Metabolism of small molecules Biosynthesis of cofactors, carriers Biotin 'birA' 'bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor' ecoli2433 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'b2482' 'hydrogenase 4 membrane subunit(1st module)' Validation Accuracy: 7/10 (70.00%) Validation Frequency class 'Energy metabolism carbon': 44/471 (9.34%) Validation Significance: dev(6.59) ; prob(5.551681E-06) ------------------ Rule 47: (8, lift 36.7) amino_acid_pair_ratio_cm <= 0 [hom( A ),classification( A ,bacillaceae)] = 1 [hom( A ),e_val_lteq( A ,0.0006),species( A ,oenothera_bertiana__bertero_s_evening_primrose_)] = 0 [hom( A ),psi_iter_lteq( A ,7),classification( A ,marchantia)] = 1 [hom( A ),species( A ,synechocystis_sp___strain_pcc_6803_),mol_wt_lteq( A ,32892)] = 1 [hom( A ),species( A ,mycoplasma_hyorhinis),mol_wt_lteq( A ,77359)] = 0 [hom( A ),keyword( A ,transmembrane),classification( A ,kinetoplastida)] = 0 -> class 'Ribosome constituents' [0.900] Evaluation on test data (712 items): ecoli3228 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplF' '50S ribosomal subunit protein L6' ecoli3658 - 1,5,24 Cell processes Transport/binding proteins Membrane-bound ATP synthase 'atpE' 'membrane-bound ATP synthase F0 sector subunit c' ecoli3264 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsG' '30S ribosomal subunit protein S7 initiates assembly' ecoli3238 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplV' '50S ribosomal subunit protein L22' ecoli4092 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsR' '30S ribosomal subunit protein S18' ecoli3116 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplU' '50S ribosomal subunit protein L21' ecoli3241 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplW' '50S ribosomal subunit protein L23' ecoli1457 - 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'b1486' 'ABC superfamily (membrane) paral putative membrane component of transport system' ecoli169 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsB' '30S ribosomal subunit protein S2' ecoli3229 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsH' '30S ribosomal subunit protein S8 and regulator' ecoli3219 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsD' '30S ribosomal subunit protein S4' ecoli3652 - 1,5,24 Cell processes Transport/binding proteins Membrane-bound ATP synthase 'atpC' 'membrane-bound ATP synthase F1 sector epsilon-subunit' ecoli3323 - 1,6,1 Cell processes Adaptation Adaptations, atypical conditions 'yrfH' 'heat shock protein 15 DNA/RNA binding' ecoli3258 - 2,1,4 Macromolecule metabolism Macromolecule degradation Degradation of proteins, peptides, glyco 'hofD' 'leader peptidase integral membrane protein cryptic gene integral membrane protein' ecoli3244 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsJ' '30S ribosomal subunit protein S10' Test Accuracy: 10/15 (66.67%) Test Frequency class 'Ribosome constituents': 24/712 (3.37%) Test Significance: dev(13.58) ; prob(4.867677E-12) Application to new data (2167 items): ecoli850 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0874' 'putative surface protein' ecoli1771 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1803' 'paral putative oxidoreductase(1st module)' ecoli1600 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1630' 'orf' ecoli2500 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2549' 'orf' ecoli848 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0872' 'paral putative oxidoreductase(1st module)' ecoli2853 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ygfD' 'membrane-bound ATP-binding transport protein phosphorylates AO and LAO periplasmic proteins' Frequency rule on new data: 6/2167 (0.28%) Evaluation on training data (939 items): ecoli3220 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsK' '30S ribosomal subunit protein S11' ecoli3240 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplB' '50S ribosomal subunit protein L2' ecoli1684 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplT' '50S ribosomal subunit protein L20 and regulator' ecoli3558 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpmG' '50S ribosomal subunit protein L33' ecoli1062 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpmF' '50S ribosomal subunit protein L32' ecoli3265 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsL' '30S ribosomal subunit protein S12' ecoli3222 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpmJ' '50S ribosomal subunit protein X' ecoli3233 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplN' '50S ribosomal subunit protein L14' Training Accuracy: 8/8 (100.00%) Training Frequency class 'Ribosome constituents': 23/939 (2.45%) Training Significance: dev(17.85) ; prob(1.295681E-13) Evaluation on validation data (471 items): ecoli3239 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rpsS' '30S ribosomal subunit protein S19' ecoli3236 4,2,2 Structural elements Ribosome constituents Ribosomal proteins - synthesis, modificationRiboso 'rplP' '50S ribosomal subunit protein L16' ecoli859 - 2,2,10 Macromolecule metabolism Macromolecule synthesis, modification Proteins - translation and modification 'infA' 'protein chain initiation factor IF-1' Validation Accuracy: 2/3 (66.67%) Validation Frequency class 'Ribosome constituents': 15/471 (3.18%) Validation Significance: dev(6.26) ; prob(2.945818E-03) ------------------ Rule 53: (11/1, lift 4.2) amino_acid_pair_ratio_xt <= 4.4 amino_acid_pairs_km <= 0 [hom( A ),e_val_lteq( A ,0.0006),species( A ,oenothera_bertiana__bertero_s_evening_primrose_)] = 0 [hom( A ),e_val_lteq( A ,3e-06),species( A ,corynebacterium_glutamicum)] = 0 [hom( A ),psi_iter_lteq( A ,13),species( A ,azorhizobium_caulinodans)] = 0 [hom( A ),species( A ,salmonella_typhimurium),keyword( A ,transmembrane)] = 1 [hom( A ),species( A ,mycoplasma_hyorhinis),mol_wt_lteq( A ,77359)] = 0 [hom( A ),species( A ,halobacterium_halobium),mol_wt_gt( A ,55220)] = 0 [hom( A ),mol_wt_gt( A ,55220),classification( A ,nematocera)] = 0 [hom( A ),keyword( A ,transmembrane),classification( A ,kinetoplastida)] = 0 -> class 'Transport/binding proteins' [0.846] Evaluation on test data (712 items): ecoli1913 - 4,1,5 Structural elements Cell envelop Surface structures 'fliP' 'flagellar biosynthesis' ecoli3833 1,5,22 Cell processes Transport/binding proteins MIP family 'glpF' 'MIP family facilitated diffusion of glycerol' ecoli3658 1,5,24 Cell processes Transport/binding proteins Membrane-bound ATP synthase 'atpE' 'membrane-bound ATP synthase F0 sector subunit c' ecoli2765 - 2,2,7 Macromolecule metabolism Macromolecule synthesis, modification Phospholipids 'lgt' 'phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; a major membrane phospholipid posttranslational lipid modification oflipoproteins' ecoli1436 - 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'narV' 'nitrate reductase 2 gamma subunit' ecoli3312 - 3,1,5 Metabolism of small molecules Amino acid biosynthesis Chorismate 'aroB' 'dehydroquinate synthase' ecoli2364 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'cysZ' 'required for sulfate transport' ecoli3290 1,5,14 Cell processes Transport/binding proteins FNT family 'nirC' 'FNT family transport protein' ecoli1158 - 4,1,5 Structural elements Cell envelop Surface structures 'dsbB' 'reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella' ecoli222 - 4,1,5 Structural elements Cell envelop Surface structures 'fhiA' 'flagellar biosynthesis paral putative transport protein' ecoli2404 - 3,4,1 Metabolism of small molecules Degradation of small molecules Amines 'eutG' 'ethanolamine utilization; homolog of salmonella enzyme similar to iron-containing alcohol dehydrogenase (2nd module)' ecoli879 1,5,14 Cell processes Transport/binding proteins FNT family 'focA' 'FNT family membrane protein (formate channel 1)(2nd module)' ecoli580 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'fepD' 'ABC superfamily (membrane) membrane component of ferric enterobactin (enterochelin) ABC transport' ecoli2220 - 3,2,8 Metabolism of small molecules Biosynthesis of cofactors, carriers Menaquinone, ubiquinone 'menB' 'dihydroxynaphtoic acid synthetase' ecoli3805 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'frvB' 'PTS family fructose-like enzyme IIBC component(2nd module)' ecoli4182 - 6,1,1 Global functions Global regulatory functions Global regulatory functions 'fecI' 'sigma factor in two component regulatory system wtih FecR FecR interacts wtih the periplasmic iron binding FecA' ecoli3258 - 2,1,4 Macromolecule metabolism Macromolecule degradation Degradation of proteins, peptides, glyco 'hofD' 'leader peptidase integral membrane protein cryptic gene integral membrane protein' ecoli3603 1,5,37 Cell processes Transport/binding proteins Sugar-specific PTS system 'glvB' 'Sugar Specific family of transport protein PTS system arbutin-like IIB component' Test Accuracy: 8/18 (44.44%) Test Frequency class 'Transport/binding proteins': 151/712 (21.21%) Test Significance: dev(2.41) ; prob(2.292576E-02) Application to new data (2167 items): ecoli2859 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yggB' 'involved in stability of MscS mechanosensitive channel paral putative transport protein' ecoli1340 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1369' 'orf' ecoli1597 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1627' 'orf' ecoli2945 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b3011' 'paral putative dehydrogenase' ecoli850 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0874' 'putative surface protein' ecoli1930 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1966' 'putative outer membrane protein' ecoli1213 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ychE' 'orf' ecoli1763 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1795' 'orf' ecoli2101 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yohK' 'putative seritonin transporter' ecoli4253 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjjP' 'paral putative membrane protein' ecoli1469 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1498' 'orf' ecoli1730 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1762' 'orf' ecoli823 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0847' 'putative transport protein' ecoli1600 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1630' 'orf' ecoli3534 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yibO' 'putative 23-bisphosphoglycerate-independent phosphoglycerate mutase' ecoli1342 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1371' 'orf' ecoli1500 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ydeB' 'orf' ecoli913 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0938' 'paral putative fimbrial-like protein' ecoli309 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0317' 'orf' ecoli2085 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yehU' 'paral putative sensor/kinase in regulatory system' ecoli1929 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1965' 'orf' ecoli1168 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1195' 'orf' ecoli1422 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1451' 'paral putative outer membrane receptor' ecoli3699 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3785' 'orf' ecoli2974 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ygiE' 'orf' ecoli1696 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1728' 'orf' ecoli1186 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1213' 'orf' ecoli1789 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1821' 'orf' ecoli2407 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'cchB' 'detox protein' ecoli2337 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2380' 'putative sensor protein(1st module)' ecoli1972 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yeeE' 'paral putative membrane component of transport system' ecoli2993 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ygiH' 'orf' ecoli3431 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yhiD' 'putative transport ATPase' ecoli1313 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1342' 'orf' ecoli3568 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yicG' 'orf' ecoli4164 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjgX' 'orf' ecoli3124 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yrbE' 'orf' ecoli1443 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1472' 'putative outer membrane porin protein' ecoli106 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'hofC' 'orf' ecoli3635 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yieG' 'orf (2nd module)' ecoli1928 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1964' 'putative outer membrane protein' ecoli10 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yaaH' 'orf' Frequency rule on new data: 42/2167 (1.94%) Evaluation on training data (939 items): ecoli3590 1,5,21 Cell processes Transport/binding proteins MFS family 'uhpA' 'response regulator positive activator of uhpT transcription (sensor uhpB)(1st module)' ecoli3928 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'malE' 'ABC superfamily (bind_prot) periplasmic maltose-binding protein; substrate recognition for transport and chemotaxis with chaperone properties(2nd module)' ecoli1866 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'araH' 'high-affinity L-arabinose transport system; membrane protein fragment 2' ecoli2940 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'exbB' 'uptake of enterochelin; tonB-dependent uptake of B colicins' ecoli1281 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'b1310' 'ABC superfamily (peri_perm) ABC super family transport protein peri_perm subunit' ecoli68 1,5,16 Cell processes Transport/binding proteins GPH family 'tbpA' 'ABC superfamily (periplasmic) periplasmic thiamine binding component of thiamine transport protein' ecoli2376 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'cysP' 'thiosulfate binding protein' ecoli4255 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'yjjR' '2-component transcriptional regulator' ecoli830 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'potF' 'ABC superfamily (peri_perm) periplasmic putrescine-binding protein ABC transport system(1st module)' ecoli4180 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'fecA' 'outer membrane receptor; citrate-dependent iron transport outer membrane receptor(1st module)' ecoli3728 1,5,23 Cell processes Transport/binding proteins Mechanism not stated 'corA' 'Mg2+ transport system I' Training Accuracy: 10/11 (90.91%) Training Frequency class 'Transport/binding proteins': 187/939 (19.91%) Training Significance: dev(5.90) ; prob(8.839213E-07) Evaluation on validation data (471 items): ecoli1969 - 4,1,2 Structural elements Cell envelop Murein sacculus, peptidoglycan 'yeeC' 'paral putative carboxypeptidase penicillin binding protein 6b (1st module)' ecoli2171 - 2,2,3 Macromolecule metabolism Macromolecule synthesis, modification DNA - replication, repair, restraction/modification 'ada' 'O6-methylguanine-DNA methyltransferase; transcription activator/repressor(1st module)' ecoli3376 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'ugpB' 'ABC superfamily (peri_perm) ABC super family transport protein peri_perm subunit sn-glycerol 3-phosphate periplasmic binding protein of ABC transport system(2nd module)' ecoli392 - 6,1,1 Global functions Global regulatory functions Global regulatory functions 'phoR' 'positive and negative sensor protein for pho regulon (and asr gene)(2nd module)' ecoli579 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'fepG' 'ABC superfamily (membrane) ferric enterobactin transport protein' ecoli403 1,5,29 Cell processes Transport/binding proteins Outer membrane channel 'tsx' 'nucleoside channel; receptor of phage T6 and colicin K' ecoli1411 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'b1440' 'ABC superfamily (peri_perm) ABC superfamily of transport protein peri_perm subunit' ecoli3823 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'sbp' 'periplasmic sulfate-binding protein' ecoli2519 - 1,2,1 Cell processes Chromosome replication Chromosome replication 'lepB' 'leader peptidase (signal peptidase I)' ecoli3821 1,5,6 Cell processes Transport/binding proteins CDF family 'yiiP' 'CDF family of transport protein (1st module)' Validation Accuracy: 6/10 (60.00%) Validation Frequency class 'Transport/binding proteins': 104/471 (22.08%) Validation Significance: dev(2.89) ; prob(8.971695E-03) ------------------ Rule 3: (23, lift 18.8) amino_acid_pair_ratio_la <= 20.1 amino_acid_pair_ratio_mv <= 5.4 amino_acid_pair_ratio_ng <= 13.1 amino_acid_pair_ratio_xr <= 2.5 amino_acid_pair_ratio_yi <= 2.7 amino_acid_pair_ratio_yw <= 1.7 [hom( A ),e_val_gt( A ,2e-37),classification( A ,firmicutes)] = 1 [hom( A ),e_val_lteq( A ,0.0006),mol_wt_lteq( A ,32892)] = 1 [hom( A ),e_val_lteq( A ,0.0006),species( A ,streptococcus_mutans)] = 0 [hom( A ),e_val_lteq( A ,3e-06),classification( A ,pulmonata)] = 0 [hom( A ),e_val_lteq( A ,3e-06),species( A ,corynebacterium_glutamicum)] = 1 [hom( A ),e_val_lteq( A ,3e-06),species( A ,rhizobium_leguminosarum)] = 0 [hom( A ),e_val_lteq( A ,6e-14),classification( A ,florideophyceae)] = 0 [hom( A ),psi_iter_lteq( A ,13),mol_wt_lteq( A ,32892)] = 1 -> class 'Amino acid biosynthesis' [0.960] Evaluation on test data (712 items): ecoli26 - 2,2,1 Macromolecule metabolism Macromolecule synthesis, modification Amino acyl tRNA syn; tRNA modification 'ileS' 'isoleucine tRNA synthetase' ecoli847 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'poxB' 'pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors cytoplasmic in absence of cofactors (2nd module) (2nd module)' ecoli3863 3,1,2 Metabolism of small molecules Amino acid biosynthesis Arginine 'argE' 'acetylornithine deacetylase(1st module)' ecoli1592 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'malY' 'enzyme that may degrade or block biosynthesis of endogenous mal inducer probably aminotrasferase(2nd module)' ecoli3946 - 2,2,3 Macromolecule metabolism Macromolecule synthesis, modification DNA - replication, repair, restraction/modification 'dnaB' 'chromosome replication; chain elongation; part of primosome' ecoli1822 - 3,5,5 Metabolism of small molecules Energy metabolism, carbon Glycolysis 'pykA' 'pyruvate kinase II glucose stimulated' ecoli3980 - 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'yjcV' 'ABC superfamily (membrane) membrane component of allose ABC transport system(1st module)' ecoli1279 - 5,1,2 Extrachromosomal Laterally acquirred elements Phage-related functions and prophages 'pspE' 'phage shock protein' ecoli1716 - 3,4,2 Metabolism of small molecules Degradation of small molecules Amino acids 'b1748' 'succinylornithine transaminase; induced by ornithine 2.6.1.-' ecoli1234 3,1,19 Metabolism of small molecules Amino acid biosynthesis Tryptophan 'trpD' 'anthranilate synthase component II glutamine amidotransferase and phosphoribosylanthranilate transferase(1st module)' ecoli3948 3,1,20 Metabolism of small molecules Amino acid biosynthesis Tyrosine 'tyrB' 'tyrosine aminotransferase tyrosine repressible' ecoli3986 - 3,3,13 Metabolism of small molecules Central intermediary metabolism Phosphorus compounds 'phnP' 'phosphonate metabolism ( according to Wanner Biodegradation 1994 5:175-184: (C-P) lyase component possibly accessory protein)' ecoli4144 3,1,2 Metabolism of small molecules Amino acid biosynthesis Arginine 'argI' 'ornithine carbamoyltransferase 1(1st module)' ecoli77 3,1,21 Metabolism of small molecules Amino acid biosynthesis Valine 'ilvI' 'acetolactate synthase III valine sensitive large subunit (2nd module)' ecoli3204 3,1,5 Metabolism of small molecules Amino acid biosynthesis Chorismate 'aroE' 'dehydroshikimate reductase' ecoli4011 - 3,4,2 Metabolism of small molecules Degradation of small molecules Amino acids 'adi' 'arginine decarboxylase; inducible by acid catabolic' ecoli4061 - 2,2,1 Macromolecule metabolism Macromolecule synthesis, modification Amino acyl tRNA syn; tRNA modification 'miaA' 'delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase' Test Accuracy: 6/17 (35.29%) Test Frequency class 'Amino acid biosynthesis': 35/712 (4.92%) Test Significance: dev(5.79) ; prob(1.090042E-04) Application to new data (2167 items): ecoli2886 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2951' 'orf' ecoli2211 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2253' 'paral putative regulator protein' ecoli2613 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2668' 'orf(1st module)' ecoli3299 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhfS' 'orf' ecoli1028 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yceA' 'orf' ecoli2472 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'sseA' 'enhances serine sensitivity (inhibits homoserine deHase) on lactate; rhodanese-like protein' ecoli3533 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yibN' 'orf' ecoli1884 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1919' 'paral putative dehydratase (2nd module)' ecoli4229 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yjiR' 'paral putative regulator protein' ecoli3640 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yieL' 'putative xylanase' ecoli902 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0927' 'orf' ecoli2336 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2379' 'paral putative regulator protein' ecoli323 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0331' 'PrpB propionate catabolism operon' ecoli507 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0516' 'putative hydantoin utilization protein' ecoli2650 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2710' 'putative flavodoxin' ecoli3788 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yihU' 'paral putative oxidoreductase(1st module)' ecoli2807 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2871' 'paral putative dehydratase(2nd module)' ecoli3081 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yraO' 'orf' Frequency rule on new data: 18/2167 (0.83%) Evaluation on training data (939 items): ecoli3846 3,1,14 Metabolism of small molecules Amino acid biosynthesis Methionine 'metL' 'aspartokinase II(1st module) bifunctional enxyme: N-teminal is aspartokinase II and C-terminal is homoserine dehydrogenase II' ecoli3918 3,1,13 Metabolism of small molecules Amino acid biosynthesis Lysine 'lysC' 'aspartokinase III lysine sensitive' ecoli3282 3,1,2 Metabolism of small molecules Amino acid biosynthesis Arginine 'argD' 'acetylornithine delta-aminotransferase (NAcOATase) (EC 2 6 1 11)' ecoli903 3,1,4 Metabolism of small molecules Amino acid biosynthesis Aspartate 'aspC' 'aspartate aminotransferase' ecoli3865 3,1,2 Metabolism of small molecules Amino acid biosynthesis Arginine 'argB' 'acetylglutamate kinase' ecoli74 3,1,12 Metabolism of small molecules Amino acid biosynthesis Leucine 'leuA' '2-isopropylmalate synthase(1st module)' ecoli2848 3,1,17 Metabolism of small molecules Amino acid biosynthesis Serine 'serA' 'D-3-phosphoglycerate dehydrogenase(1st module)' ecoli2546 3,1,15 Metabolism of small molecules Amino acid biosynthesis Phenylalanine 'pheA' 'bifuctional chorismate mutase-P and prephenate dehydratase(1st module)' ecoli2775 3,1,13 Metabolism of small molecules Amino acid biosynthesis Lysine 'lysA' 'diaminopimelate decarboxylase(2nd module)' ecoli3592 3,1,21 Metabolism of small molecules Amino acid biosynthesis Valine 'ilvB' 'acetolactate synthase Ivaline-sensitive large subunit (2nd module)' ecoli2502 3,1,9 Metabolism of small molecules Amino acid biosynthesis Glycine 'glyA' 'serine hydroxymethyltransferase' ecoli2755 3,1,2 Metabolism of small molecules Amino acid biosynthesis Arginine 'argA' 'N-acetylglutamate synthase (aa acetyl transferase)(1st module)' ecoli2423 3,1,13 Metabolism of small molecules Amino acid biosynthesis Lysine 'dapE' 'N-succinyl-diaminopimelate deacylase(1st module)' ecoli265 3,1,2 Metabolism of small molecules Amino acid biosynthesis Arginine 'argF' 'ornithine carbamoyltransferase 2 chain F first part(1st module)' ecoli3845 3,1,14 Metabolism of small molecules Amino acid biosynthesis Methionine 'metB' 'cystathionine gamma-synthase' ecoli2548 3,1,5 Metabolism of small molecules Amino acid biosynthesis Chorismate 'aroF' '3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase tyrosine repressible)' ecoli2372 3,1,6 Metabolism of small molecules Amino acid biosynthesis Cysteine 'cysM' 'cysteine synthase B O-acetylserine sulfhydrolase B(1st module)' ecoli235 3,1,16 Metabolism of small molecules Amino acid biosynthesis Proline 'proB' 'gamma-glutamate kinase' ecoli1232 3,1,19 Metabolism of small molecules Amino acid biosynthesis Tryptophan 'trpB' 'tryptophan synthase beta protein(1st module)' ecoli380 3,1,5 Metabolism of small molecules Amino acid biosynthesis Chorismate 'aroL' 'shikimate kinase II' ecoli730 3,1,15 Metabolism of small molecules Amino acid biosynthesis Phenylalanine 'aroG' '3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase phenylalanine repressible)' ecoli2429 3,1,13 Metabolism of small molecules Amino acid biosynthesis Lysine 'dapA' 'dihydrodipicolinate synthase' ecoli4 3,1,18 Metabolism of small molecules Amino acid biosynthesis Threonine 'thrC' 'threonine synthase' Training Accuracy: 23/23 (100.00%) Training Frequency class 'Amino acid biosynthesis': 48/939 (5.11%) Training Significance: dev(20.66) ; prob(1.982622E-30) Evaluation on validation data (471 items): ecoli31 3,1,13 Metabolism of small molecules Amino acid biosynthesis Lysine 'dapB' 'dihydrodipicolinate reductase' ecoli911 - 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'b0936' 'probable ABC superfamily binding component aliphatic sulphonates binding protein' ecoli3155 - 4,1,4 Structural elements Cell envelop Surface polysaccharides & antigens 'nanA' 'N-acetylneuraminate lyase (aldolase); catabolism of sialic acid; not K-12?' ecoli4097 - 2,2,9 Macromolecule metabolism Macromolecule synthesis, modification Protein modufication 'fklB' 'FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase)' ecoli2 3,1,18 Metabolism of small molecules Amino acid biosynthesis Threonine 'thrA' 'aspartokinase I(1st module) bifunctional enxyme N-terminal is aspartokinaseI and C-terminal is homoserine dehydrogenase I' ecoli2942 3,1,14 Metabolism of small molecules Amino acid biosynthesis Methionine 'metC' 'cystathionine beta-lyase (beta-cystathionase)' ecoli1729 3,1,7 Metabolism of small molecules Amino acid biosynthesis Glutamate 'gdhA' 'NADP-specific glutamate dehydrogenase' ecoli1188 - 4,1,4 Structural elements Cell envelop Surface polysaccharides & antigens 'kdsA' '3-deoxy-D-manno-octulosonic acid 8-P synthetase' ecoli3682 3,1,21 Metabolism of small molecules Amino acid biosynthesis Valine 'ilvG_1' 'acetolactate synthase II large subunit cryptic fragment 1 first part(1st module)' ecoli3631 - 1,5,21 Cell processes Transport/binding proteins MFS family 'yidY' 'MFS family of tranport protein (1st mdule)' ecoli3494 3,1,1 Metabolism of small molecules Amino acid biosynthesis Alanine 'avtA' 'alanine-alpha-ketoisovalerate (or valine-pyruvate) transaminase transaminase C' Validation Accuracy: 6/11 (54.55%) Validation Frequency class 'Amino acid biosynthesis': 24/471 (5.10%) Validation Significance: dev(7.46) ; prob(6.226114E-06) ------------------ Rule 38: (3, lift 18.3) amino_acid_pair_ratio_gc <= 1.4 amino_acid_pairs_wt > 1 [hom( A ),e_val_lteq( A ,0.0006),species( A ,oenothera_bertiana__bertero_s_evening_primrose_)] = 0 [hom( A ),species( A ,mycoplasma_hyorhinis),mol_wt_lteq( A ,77359)] = 0 [hom( A ),mol_wt_lteq( A ,55220),classification( A ,alpha_subdivision)] = 1 -> class 'Macromolecule degradation' [0.800] Evaluation on test data (712 items): ecoli3349 - 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'glpD' 'sn-glycerol-3-phosphate dehydrogenase (aerobic)' ecoli2241 - 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoG' 'NADH dehydrogenase I chain G' ecoli728 - 1,5,6 Cell processes Transport/binding proteins CDF family 'b0752' 'CDF family of transport protein (1st module)' ecoli2223 - 3,2,8 Metabolism of small molecules Biosynthesis of cofactors, carriers Menaquinone, ubiquinone 'menF' 'isochorismate hydroxymutase 2/isochorismate synthase menaquinone biosynthesis' ecoli1162 - 3,4,2 Metabolism of small molecules Degradation of small molecules Amino acids 'dadA' 'D-amino acid dehydrogenase subunit' ecoli149 - 4,1,2 Structural elements Cell envelop Murein sacculus, peptidoglycan 'mrcB' 'peptidoglycan synthetase; penicillin-binding protein 1b (3rd module transpeptidase)' ecoli3198 - 1,5,3 Cell processes Transport/binding proteins ABC superfamily (peri_perm) 'yhdW' 'ABC superfamily (peri_perm) ABC superfamily of transport protein (1st module peri_perm subunit)' Test Accuracy: 0/7 (0.00%) Test Frequency class 'Macromolecule degradation': 20/712 (2.81%) Test Significance: dev(-0.45) ; prob(1.000000E+00) Application to new data (2167 items): ecoli1433 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1462' 'orf' ecoli3437 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yhiV' 'paral putative membrane component of transport system (3rd module)' ecoli3035 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yqjG' 'putative transferase' ecoli1770 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1802' 'putative dioxygenase alpha subunit yeaw' ecoli744 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'ybhD' 'paral putative regulator' ecoli2808 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2872' 'paral putative deacetylase(1st module)' ecoli2026 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yegE' 'orf' Frequency rule on new data: 7/2167 (0.32%) Evaluation on training data (939 items): ecoli907 2,1,4 Macromolecule metabolism Macromolecule degradation Degradation of proteins, peptides, glyco 'pepN' 'aminopeptidase N' ecoli3454 2,1,3 Macromolecule metabolism Macromolecule degradation Degradation of polysaccharides 'yhjM' 'Endo-14-D-glucanase' ecoli3493 2,1,3 Macromolecule metabolism Macromolecule degradation Degradation of polysaccharides 'malS' 'alpha-amylase(2nd module)' Training Accuracy: 3/3 (100.00%) Training Frequency class 'Macromolecule degradation': 41/939 (4.37%) Training Significance: dev(8.11) ; prob(8.324436E-05) Evaluation on validation data (471 items): ecoli1734 2,1,4 Macromolecule metabolism Macromolecule degradation Degradation of proteins, peptides, glyco 'sppA' 'protease IV a signal peptide peptidase(2nd module)' ecoli2727 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'b2787' '(D)-glucarate dehydratase (GlucD)' Validation Accuracy: 1/2 (50.00%) Validation Frequency class 'Macromolecule degradation': 11/471 (2.34%) Validation Significance: dev(4.46) ; prob(4.561826E-02) ------------------ Rule 19: (15, lift 9.9) amino_acid_pair_ratio_wp <= 0 [hom( A ),classification( A ,carnivora)] = 1 [hom( A ),classification( A ,corynebacteriaceae)] = 0 [hom( A ),keyword( A ,transmembrane),classification( A ,kinetoplastida)] = 1 [hom( A ),keyword( A ,inner_membrane),classification( A ,epsilon_subdivision)] = 0 -> class 'Energy metabolism carbon' [0.941] Evaluation on test data (712 items): ecoli2241 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoG' 'NADH dehydrogenase I chain G' ecoli4248 - 1,6,2 Cell processes Adaptation Osmotic adaptation 'mdoB' 'phosphoglycerol transferase I add phosphoglycerols to OPG backbone' ecoli2246 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoA' 'NADH dehydrogenase I chain A' ecoli2435 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'b2484' 'hydrogenase 4 membrane subunit(1st module)' ecoli2201 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'glpC' 'sn-glycerol-3-phosphate dehydrogenase (anaerobic) K-small subunit(2nd module)' ecoli3308 - 3,4,3 Metabolism of small molecules Degradation of small molecules Carbon compounds 'gph' 'phosphoglycolate phosphatase' ecoli2660 3,5,4 Metabolism of small molecules Energy metabolism, carbon Fermentation 'hycF' 'probable iron-sulfur protein of hydrogenase 3 (part of FHL complex)' ecoli2664 3,5,4 Metabolism of small molecules Energy metabolism, carbon Fermentation 'hycB' 'probable small subunit of hydrogenase-3 iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)' ecoli3392 - 1,5,30 Cell processes Transport/binding proteins P-type ATPase family 'b3469' 'P-type ATPase familyzinc-transporting ATPase(2nd module)' Test Accuracy: 6/9 (66.67%) Test Frequency class 'Energy metabolism carbon': 70/712 (9.83%) Test Significance: dev(5.73) ; prob(5.828026E-05) Application to new data (2167 items): ecoli2022 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2063' 'orf (2nd module)' ecoli2251 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2293' 'orf' ecoli299 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'ykgF' 'orf' ecoli798 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0822' 'orf' ecoli1642 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1674' 'paral putative oxidoreductase' ecoli3495 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b3573' 'paral putative oxidoreductase' ecoli2835 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2899' 'putative oxidoreductase' ecoli1919 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1955' 'orf' ecoli438 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'cof' 'complements deletion mutant for growth on succinate(1st module)' ecoli1559 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1589' 'paral putative oxidoreductase Fe-S subunit' ecoli3618 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yidA' 'orf' ecoli2513 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2562' 'orf' ecoli1639 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1671' 'paral putative oxidoreductase (2nd module)' ecoli4260 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yjjG' 'orf' ecoli820 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0844' 'orf' ecoli3861 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yijP' 'orf (2nd module)' ecoli1695 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1727' 'orf' ecoli966 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b0992' 'orf' ecoli1379 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1408' 'probable enzyme' ecoli2133 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2174' 'orf' ecoli2106 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yeiA' 'paral putative dihydro-orotate oxidase(2nd module)' ecoli1655 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b1687' 'paral putative oxidase(1st module)' ecoli999 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1025' 'orf(2nd module) homologue of Yersinia pestis hmsT involved in haemin uptake/storage ?cryptic' ecoli1784 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b1816' 'orf (2nd module)' ecoli2822 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2886' 'paral putative oxidoreductase' ecoli355 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b0363' 'polysaccharide metabolism(1st module)' ecoli2309 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'b2352' 'paral putative ligase(1st module)' ecoli200 - 7,0,0 Miscellaneous Some information, but not classifiable Not classified (included putative assignments) 'yaeD' 'paral putative enzyme' ecoli3394 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'yhhQ' 'orf(1st module)' ecoli3636 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b3715' 'orf' ecoli2212 - 0,0,0 Open reading frames Unknown proteins, no known homologs Unknown function 'b2254' 'orf(1st module)' Frequency rule on new data: 31/2167 (1.43%) Evaluation on training data (939 items): ecoli3799 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'fdoH' 'formate dehydrogenase-o fe-s subunit (2nd module)' ecoli3966 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'nrfC' 'putative nitrite reductase; formate-dependent Fe-S centers(1st module)' ecoli1446 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'fdnH' 'formate dehydrogenase-N nitrate-inducible Fe-S beta subunit' ecoli1198 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'narH' 'nitrate reductase 1 beta subunit(2nd module)' ecoli870 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'dmsB' 'anaerobic dimethyl sulfoxide reductase subunit B' ecoli2238 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoJ' 'NADH dehydrogenase I chain J(1st module)' ecoli2653 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'hydN' 'involved in electron transport from formate to hydrogen Fe-S centers' ecoli2163 3,5,3 Metabolism of small molecules Energy metabolism, carbon Electron transport 'napG' 'ferredoxin-type protein: electron transfer' ecoli2930 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'hybA' 'thought to be hydrogenase-2 small subunit now identified as hybO(2nd module)' ecoli2162 3,5,3 Metabolism of small molecules Energy metabolism, carbon Electron transport 'napH' 'ferredoxin-type protein: electron transfer(1st module)' ecoli422 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'cyoC' 'cytochrome o ubiquinol oxidase subunit III' ecoli2235 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoM' 'NADH dehydrogenase I chain M(2nd module)' ecoli2166 3,5,3 Metabolism of small molecules Energy metabolism, carbon Electron transport 'napF' 'ferredoxin-type protein: electron transfer' ecoli2432 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'yffE' 'hydrogenase 4 Fe-S subunit' ecoli4046 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'frdB' 'fumarate reductase anaerobic Fe-S protein subunit EC 1.3.99.1' Training Accuracy: 15/15 (100.00%) Training Frequency class 'Energy metabolism carbon': 89/939 (9.48%) Training Significance: dev(11.97) ; prob(4.475754E-16) Evaluation on validation data (471 items): ecoli2157 - 1,5,2 Cell processes Transport/binding proteins ABC superfamily (membrane) 'ccmC' 'ABC superfamily (membrane)heme exporter protein C necessary for incorporation of heme into CcmE (cytochrome c-type biogenesis protein)' ecoli1598 - 3,3,15 Metabolism of small molecules Central intermediary metabolism Pool, multipurpose conversions of intermed. met'm 'b1628' 'PUTATIVE FERREDOXIN-LIKE PROTEIN' ecoli2239 3,5,1 Metabolism of small molecules Energy metabolism, carbon Aerobic respiration 'nuoI' 'NADH dehydrogenase I chain I' ecoli2439 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'b2488' 'hydrogenase 4 Fe-S subunit' ecoli1438 3,5,2 Metabolism of small molecules Energy metabolism, carbon Anaerobic respiration 'narY' 'nitrate reductase 2 beta subunit(1st module)' ecoli2887 - 1,4,3 Cell processes Protection responses Drug/analog sensitivity 'b2952' 'putative resistance protein' Validation Accuracy: 3/6 (50.00%) Validation Frequency class 'Energy metabolism carbon': 44/471 (9.34%) Validation Significance: dev(3.42) ; prob(1.214916E-02) ------------------