Rule 182: yeast_to_yeast(_1,_2,b0.0_2.0e-7),eval(_1,_3,b4.0e-4_4.5e-2),classification(_3,leishmania) = 1 eval(_1,_2,gte1.1),classification(_2,rhizobium),keyword(_2,transmembrane) = 1 eval(_1,_2,gte1.1),classification(_2,candida),db_ref(_2,prosite) = 1 eval(_1,_2,b0.0_1.0e-8),sq_len(_2,b16_344),classification(_2,borrelia) = 0 -> class 67/4/1/2 "other cation transporters (Na, K, Ca , NH4, etc.)" Evaluation on training data (483 items): ytyel027w 11,7,0,0 "CUP5" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 13,1,1,3 "CUP5" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 40,25,0,0 "CUP5" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 67,4,1,2 "CUP5" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 67,50,22,0 "CUP5" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 8,13,0,0 "CUP5" "H+-ATPase V0 domain 17 KD subunit, vacuolar" ytygl167c 13,1,1,99 "PMR1" "Ca2+-transporting P-type ATPase" 40,8,0,0 "PMR1" "Ca2+-transporting P-type ATPase" 67,4,1,2 "PMR1" "Ca2+-transporting P-type ATPase" 67,50,22,0 "PMR1" "Ca2+-transporting P-type ATPase" 8,7,0,0 "PMR1" "Ca2+-transporting P-type ATPase" ytyal026c 40,8,0,0 "DRS2" "P-type amino-phospholipids-ATPase" 67,4,1,2 "DRS2" "P-type amino-phospholipids-ATPase" 67,50,22,0 "DRS2" "P-type amino-phospholipids-ATPase" 8,7,0,0 "DRS2" "P-type amino-phospholipids-ATPase" ytypl234c 13,1,1,3 "TFP3" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 40,25,0,0 "TFP3" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 6,10,0,0 "TFP3" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 67,4,1,2 "TFP3" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 67,50,22,0 "TFP3" "H+-ATPase V0 domain 17 KD subunit, vacuolar" 8,13,0,0 "TFP3" "H+-ATPase V0 domain 17 KD subunit, vacuolar" ytyhl016c 13,1,1,99 "DUR3" "urea transport protein" 13,1,3,99 "DUR3" "urea transport protein" 40,2,0,0 "DUR3" "urea transport protein" 67,4,1,2 "DUR3" "urea transport protein" 67,4,7,0 "DUR3" "urea transport protein" ytypl036w 13,1,1,3 "PMA2" "H+-transporting P-type ATPase, minor isoform, plasma membrane" 40,2,0,0 "PMA2" "H+-transporting P-type ATPase, minor isoform, plasma membrane" 67,4,1,2 "PMA2" "H+-transporting P-type ATPase, minor isoform, plasma membrane" 67,50,22,0 "PMA2" "H+-transporting P-type ATPase, minor isoform, plasma membrane" ytyhr026w 40,25,0,0 "PPA1" "H+-ATPase 23 KD subunit, vacuolar" 67,4,1,2 "PPA1" "H+-ATPase 23 KD subunit, vacuolar" 67,50,22,0 "PPA1" "H+-ATPase 23 KD subunit, vacuolar" ytq0085 - 13,1,1,3 "ATP6" "F1F0-ATPase complex, FO A subunit" 2,13,0,0 "ATP6" "F1F0-ATPase complex, FO A subunit" 40,16,0,0 "ATP6" "F1F0-ATPase complex, FO A subunit" 67,50,22,0 "ATP6" "F1F0-ATPase complex, FO A subunit" 8,4,0,0 "ATP6" "F1F0-ATPase complex, FO A subunit" ytybr235w 13,1,1,99 "null" "similarity to bumetanide-sensitive Na-K-Cl cotransport protein" 13,1,3,5 "null" "similarity to bumetanide-sensitive Na-K-Cl cotransport protein" 67,4,1,2 "null" "similarity to bumetanide-sensitive Na-K-Cl cotransport protein" 67,4,7,0 "null" "similarity to bumetanide-sensitive Na-K-Cl cotransport protein" ytyjl094c 13,1,1,3 "KHA1" "K+/H+ exchanger" 13,1,1,99 "KHA1" "K+/H+ exchanger" 67,4,1,2 "KHA1" "K+/H+ exchanger" ytydr456w 11,1,0,0 "NHX1" "NA+-H+ antiporter" 13,1,1,3 "NHX1" "NA+-H+ antiporter" 13,1,1,99 "NHX1" "NA+-H+ antiporter" 40,16,0,0 "NHX1" "NA+-H+ antiporter" 67,4,1,2 "NHX1" "NA+-H+ antiporter" 8,7,0,0 "NHX1" "NA+-H+ antiporter" Training Accuracy: 10/11 (90.91%) Training Frequency class '67/4/1/2': 18/483 (3.73%) Evaluation on validation data (247 items): ytydl128w 13,1,1,3 "VCX1" "Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar" 13,1,1,99 "VCX1" "Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar" 40,25,0,0 "VCX1" "Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar" 67,4,1,2 "VCX1" "Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar" 8,13,0,0 "VCX1" "Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar" ytymr023c - 4,5,5,1 "MSS1" "mitochondrial GTPase involved in expression of COX1" 40,16,0,0 "MSS1" "mitochondrial GTPase involved in expression of COX1" 5,4,0,0 "MSS1" "mitochondrial GTPase involved in expression of COX1" 5,7,0,0 "MSS1" "mitochondrial GTPase involved in expression of COX1" ytyjr117w - 14,4,3,3 "STE24" "zinc metallo-protease" 40,7,0,0 "STE24" "zinc metallo-protease" 6,7,0,0 "STE24" "zinc metallo-protease" ytyel031w 13,1,1,99 "SPF1" "P-type ATPase" 67,4,1,2 "SPF1" "P-type ATPase" 67,50,22,0 "SPF1" "P-type ATPase" Validation Accuracy: 2/4 (50.00%) Validation Frequency class '67/4/1/2': 8/247 (3.24%) Evaluation on propertest data (370 items): ytybr296c - 1,4,7,0 "PHO89" "Na+-coupled phosphate transport protein, high affinity" 13,1,1,99 "PHO89" "Na+-coupled phosphate transport protein, high affinity" 13,1,3,3 "PHO89" "Na+-coupled phosphate transport protein, high affinity" 67,4,7,0 "PHO89" "Na+-coupled phosphate transport protein, high affinity" ytydr038c - 13,1,1,99 "ENA5" "P-type ATPase involved in Na+ efflux" 67,50,22,0 "ENA5" "P-type ATPase involved in Na+ efflux" ytygl006w 13,1,1,99 "PMC1" "Ca2+-transporting P-type ATPase" 40,25,0,0 "PMC1" "Ca2+-transporting P-type ATPase" 67,4,1,2 "PMC1" "Ca2+-transporting P-type ATPase" 67,50,22,0 "PMC1" "Ca2+-transporting P-type ATPase" 8,13,0,0 "PMC1" "Ca2+-transporting P-type ATPase" ytygl008c 13,1,1,3 "PMA1" "H+-transporting P-type ATPase, major isoform, plasma membrane" 40,2,0,0 "PMA1" "H+-transporting P-type ATPase, major isoform, plasma membrane" 67,4,1,2 "PMA1" "H+-transporting P-type ATPase, major isoform, plasma membrane" 67,50,22,0 "PMA1" "H+-transporting P-type ATPase, major isoform, plasma membrane" ytypr003c - 13,1,3,1 "null" "similarity to sulphate transporter proteins" 67,4,7,0 "null" "similarity to sulphate transporter proteins" Propertest Accuracy: 2/5 (40.00%) Propertest Frequency class '67/4/1/2': 10/370 (2.70%) New (unknown) data (247 items): ytymr155w - 99,0,0,0 "null" "weak similarity to E.coli hypothetical protein f402" ytykr030w - 99,0,0,0 "null" "weak similarity to NADH dehydrogenases" ytq0144 - 99,0,0,0 "null" "questionable ORF" ytynl305c - 99,0,0,0 "null" "similarity to C-term. of A.nidulans regulatory protein (qutR)" ytymr034c - 99,0,0,0 "null" "weak similarity to YPR201w" ytyml018c - 99,0,0,0 "null" "similarity to YDR438w" ytybr187w - 99,0,0,0 "null" "similarity to mouse putative transmembrane protein FT27" ytydl222c - 99,0,0,0 "null" "strong similarity to hypothetical protein YNL194c and similarity to YML052w" ytylr414c - 99,0,0,0 "null" "weak similarity to YLR413w" ytynl326c - 99,0,0,0 "null" "similarity to YOL003c, YLR246w and C.elegans hypothetical protein ZK757.1" ytypl264c - 99,0,0,0 "null" "strong similarity to YMR253c" ytynl275w - 98,0,0,0 "null" "similarity to human band 3 anion transport protein" ytybr004c - 99,0,0,0 "null" "similarity to S.pombe hypothetical protein SPAC18B11.05" ytydl054c - 99,0,0,0 "null" "similarity to hypothetical protein C. albicans" ytybr147w - 99,0,0,0 "null" "strong similarity to hypothetical protein YOL092w" ytydr338c - 99,0,0,0 "null" "similarity to ERC1P" ytybr025c - 99,0,0,0 "null" "strong similarity to Ylf1p" ytydr411c - 99,0,0,0 "null" "weak similarity to DER1P" ------------------