Dr Iain Chalmers

PhD

Dr Iain Chalmers

Lecturer in Veterinary Biosciences

IBERS

Contact Details

Profile

2013-present
Lecturer in Veterinary Biosciences, IBERS, Aberstwyth University, UK
2010-2013
EU-funded Post-Doctoral Research Associate, IBERS, Aberystwyth University, UK
2008-2009
Research Technician, IBERS, Aberystwyth University, UK
2002-2009
Wellcome Trust PhD programme, under supervision of Dr. Karl Hoffmann, Department of Pathology, University of Cambridge, UK
1998-2002
BSc (Hons.) Degree in Immunology, Edinburgh University, UK

Teaching

Research

My research focuses on the identification and characterisation of helminth proteins essential to the parasites survival in the host. The aim of this research is to discover novel vaccine candidates/drug targets and to also gain a deeper understanding of host/parasite interactions. Using bioinformatic approaches, my research also examines the evolution of gene families (such as the SmVAL family) across parasitic and non-parasitic species.

Publications

Farias, LP, Chalmers, IW, Perally, S, Rofatto, HK, Jackson, CJ, Brown, M, Khouri, MI, Barbosa, MMF, Hensbergen, PJ, Hokke, CH, Leite, LCC & Hoffmann, KF 2019, 'Schistosoma mansoni venom allergen-like proteins: phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity' International Journal for Parasitology. https://doi.org/10.1016/j.ijpara.2019.03.003
Egesa, M, Lubyayi, L, Jones, FM, van Diepen, A, Chalmers, I, Tukahebwa, EM, Bagaya, BS, Hokke, CH, Hoffmann, K, Dunne, DW, Elliot, AM, Yazdanbakhsh, M, Wilson, S & Cose, S 2018, 'Antibody Responses to Schistosoma mansoni Schistosomula Antigens' Parasite Immunology, vol. 40, no. 12, e12591. https://doi.org/10.1111/pim.12591
Padalino, G, Ferla, S, Brancale, A, Chalmers, I & Hoffmann, K 2018, 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' International Journal for Parasitology: Drugs and Drug Resistance, vol. 8, no. 3, pp. 559-570. https://doi.org/10.1016/j.ijpddr.2018.10.005
Egesa, M, Lubyayi, L, Tukahebwa, EM, Bagaya, BS, Chalmers, I, Wilson, S, Hokke, CH, Hoffmann, K, Dunne, DW, Yazdanbakhsh, M, Labuda, LA & Cose, S 2018, 'S. mansoni Schistosomula Antigens Induce Th1/Proinflammatory Cytokine Responses' Parasite Immunology. https://doi.org/10.1111/pim.12592
Geyer, K, Niazi, U, Duval, D, Cosseau, C, Tomlinson, C, Chalmers, I, Swain, M, Cutress, D, Bickham-Wright, U, Munshi, SE, Grunau, C, Yoshino, TP & Hoffmann, K 2017, 'The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni' PLoS Neglected Tropical Diseases, vol. 11, no. 5, e0005246. https://doi.org/10.1371/journal.pntd.0005246
More publications on the Research Portal