|Module Title||EVOLUTION & MOLECULAR SYSTEMATICS|
|Co-ordinator||Dr Glynis Giddings|
|Other staff||Dr Roy Goodacre, Dr Simon Creasey|
|Course delivery||Lecture||30 Hours|
|Workshop||9 Hours (3 x 3 hours)|
|Assessment||Course work||Three course work assignments||30%|
|Exam||3 Hours On 3-hour theory paper||70%|
|Resit assessment||One 3-hour theory paper (plus resubmission of failed coursework or an alternative)|
The units of selection will be discussed with reference to selfish DNA, group selection, and epigenetic inheritance. The relationship between fitness and selection will be covered, with reference to experiments that demonstrate evolution in vitro. Consideration will be given to question of why organisms do not evolve to be perfect, and why in the modern world we might expect to see maladaptation rather frequently.
The use of molecular clocks will be considered in some detail, including to trace the evolution of the AIDS virus, primates, and humans. One of the workshops will be on molecular clocks and ancestry. Molecular tools will be described for the measurement of evolution and for the screening of biodiversity among animal, plant and microbial populations. Various nucleic acid techniques will be described, including the sequencing of small sub unit ribosmal RNA, the measurement of various DNA polymorphisms via restriction fragment length polymorphisms, and the polymerase chain reaction based methods of randomly amplified polymorphic DNAs, amplified fragment length polymorphism, and microsatellites. Rudimentary analysis of data will also be covered.
The effects of genetic drift will be considered, including its importance to conservation. The importance of the founder effect, migration and inbreeding will be demonstrated using examples of human populations.
There will be a lecture and video on the evolution of sex. This will include a presentation of the arguments about why there are often only two sexes. There will be an introduction to game theory and its use in exploring the evolution of animal behaviour. This will include the evolution of sexuality, and animal aggression. The workshop on game theory will explore the evolution of co-operation and cheating.