Systems Biology Modelling: AAA Model Reactions

Reactions comprising sce:AAA logical model

4.2.1.11: phosphopyruvate hydratase reaction([C00631], <--->, [C00001, C00074]) C00631 2-Phospho-D-glycerate <---> C00001 H2O + C00074 Phosphoenolpyruvate

2.5.1.54: 3-phosphoshikimate 1-carboxyvinyltransferase reaction([C00001, C00074, C00279], <--->, [C00009, C04691]) C00001 H2O + C00074 Phosphoenolpyruvate + C00279 D-Erythrose 4-phosphate <---> C00009 Orthophosphate + C04691 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate

4.1.3.27: anthranilate synthase reaction([C00014, C00251], <--->, [C00001, C00022, C00108]) C00014 NH3 + C00251 Chorismate <---> C00001 H2O + C00022 Pyruvate + C00108 Anthranilate reaction([C00064, C00251], <--->, [C00022, C00025, C00108]) C00064 L-Glutamine + C00251 Chorismate <---> C00022 Pyruvate + C00025 L-Glutamate + C00108 Anthranilate

2.6.1.7: kynurenine-oxoglutarate transaminase reaction([C00025, C00166], <--->, [C00026, C00079]) C00025 L-Glutamate + C00166 Phenylpyruvate <---> C00026 2-Oxoglutarate + C00079 L-Phenylalanine reaction([C00025, C01179], <--->, [C00026, C00082]) C00025 L-Glutamate + C01179 3-(4-Hydroxyphenyl) pyruvate <---> C00026 2-Oxoglutarate + C00082 L-Tyrosine

2.4.2.18: anthranilate phosphoribosyltransferase reaction([C00108, C00119], <--->, [C00013, C04302]) C00108 Anthranilate + C00119 5-Phospho-alpha-D-ribose 1-diphosphate <---> C00013 Pyrophosphate + C04302 N-(5-Phospho-D-ribosyl)anthranilate

5.3.1.24: phosphoribosylanthranilate isomerase reaction([C04302], <--->, [C01302]) C04302 N-(5-Phospho-D-ribosyl)anthranilate <---> C01302 1-(2-Carboxyphenylamino)-1'-deoxy-D-ribulose 5'-phosphate

4.1.1.48: indole-3-glycerol-phosphate synthase reaction([C01302], <--->, [C00001, C00011, C03506]) C01302 1-(2-Carboxyphenylamino)-1'-deoxy-D-ribulose 5'-phosphate <---> C00001 H2O + C00011 CO2 + C03506 Indoleglycerol phosphate

4.2.1.20: tryptophan synthase reaction([C00065, C03506], <--->, [C00001, C00078, C00661]) C00065 L-Serine + C03506 Indoleglycerol phosphate <---> C00001 H2O + C00078 L-Tryptophan + C00661 Glyceraldehyde 3-phosphate reaction([C03506], <--->, [C00463, C00661]) C03506 Indoleglycerol phosphate <---> C00463 Indole + C00661 Glyceraldehyde 3-phosphate reaction([C00065, C00463], <--->, [C00001, C00078]) C00065 L-Serine + C00463 Indole <---> C00001 H2O + C00078 L-Tryptophan

5.4.99.5: chorismate mutase reaction([C00251], <--->, [C00254]) C00251 Chorismate <---> C00254 Prephenate

4.2.1.51: prephenate dehydratase reaction([C00003, C00254], <--->, [C00004, C00011, C00166]) C00003 NAD+ + C00254 Prephenate <---> C00004 NADH + C00011 CO2 + C00166 Phenylpyruvate

1.3.1.13: prephenate dehydrogenase (NADP) reaction([C00006, C00254], <--->, [C00000, C00005, C00011, C01179]) C00006 NADP+ + C00254 Prephenate <---> C00000 H+ + C00005 NADPH + C00011 CO2 + C01179 3-(4-Hydroxyphenyl)pyruvate

4.2.3.4: 3-dehydroquinate synthase reaction([C04691], <--->, [C00009, C00944]) C04691 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <---> C00009 Orthophosphate + C00944 3-Dehydroquinate

4.2.1.10: 3-dehydroquinate dehydratase reaction([C00944], <--->, [C00001, C02637]) C00944 3-Dehydroquinate <---> C00001 H2O + C02637 3-Dehydroshikimate

5.-.-.-: dehydroshikimate isomerase reaction([C02637], <--->, [C02652]) C02637 3-Dehydroshikimate <---> C02652 5-Dehydroshikimate

1.1.1.25: shikimate 5-dehydrogenase reaction([C00000, C00005, C02652], <--->, [C00006, C00493]) C00000 H+ + C00005 NADPH + C02652 5-Dehydroshikimate <---> C00006 NADP+ + C00493 Shikimate

2.7.1.71: shikimate kinase reaction([C00002, C00493], <--->, [C00008, C03175]) C00002 ATP + C00493 Shikimate <---> C00008 ADP + C03175 Shikimate 3-phosphate

2.5.1.19: 3-phosphoshikimate 1-carboxyvinyltransferase reaction([C00074, C03175], <--->, [C00009, C01269]) C00074 Phosphoenolpyruvate + C03175 Shikimate 3-phosphate <---> C00009 Orthophosphate + C01269 5-O-(1-Carboxyvinyl)-3-phosphoshikimate

4.2.3.5: chorismate synthase reaction([C01269], <--->, [C00009, C00251]) C01269 5-O-(1-Carboxyvinyl)-3-phosphoshikimate <---> C00009 Orthophosphate + C00251 Chorismate