Dr Dylan Wyn Phillips

PhD

Dr Dylan Wyn Phillips

Lecturer

Contact Details

Teaching

Module Coordinator
Lecturer
Tutor
Additional Lecturer

I have gained over 10 years of teaching experience and currently lecture about all things genetics at both undergraduate and postgraduate level. I have the pleasure of being the scheme coordinator for the Genetics degree (C400 & C401); and supervise a number of research students undertaking their PhD projects. I am also a Fellow of the Higher Education Academy and an Associate Editor for the journal Genome. I am actively involved in the development and delivery of the distance learning schemes that IBERS offers. These courses deliver innovative training modules tailored to the needs of the agri-food industry, ensuring businesses have the resilience required to meet future challenges of climate change and economic pressures.

Research

I completed my PhD at Aberystwyth and have since continued my research which focuses on understanding and manipulating the meiotic DNA repair pathways in a range of key crop species. These complex repair pathways are responsible for generating the genetically diverse populations that plant breeders select their elite lines from. The aim of the research is to enhance the transferred important traits from diverse germplasm into commercial varieties. Genome editing technology has already had a dramatic effect on how research is performed and will undoubtedly revolutionise the way plant breeding is performed. I am involved in the development and implementation of the CRISPR-Cas9 technology in IBERS, and have a keen interest in improving current plant transformation methods.

Publications

Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoniGeyer, K., Munshi, S. E., Whiteland, H., Fernandez-Fuentes, N., Phillips, D. & Hoffmann, K. 2018 (Accepted/In press) In : PLOS Pathogens.
A cytological approach to study meiotic recombination and chromosome dynamics of Arabidopsis thaliana male meiocytes in three dimensionsHurel, A., Phillips, D., Vrielynck, N., Mézard , C., Grelon, M. & Christophorou, N. 2018 In : Plant Journal.
B chromosomes are associated with redistribution of genetic recombination towards lower-recombination chromosomal regions in perennial ryegrassHarper, J., Phillips, D., Thomas, A., Gasior, D., Evans, C., Powell, W., King, J., King, I., Jenkins, G. & Armstead, I. 2018 In : Journal of Experimental Botany.69, 8
Potential impact of genome editing in world agricultureMartinez-Fortun, J., Phillips, D. & Jones, H. 2017 In : Emerging Topics in Life Sciences.1, 2, p. 117-13316 p., 2
A spontaneous mutation in MutL-Homolog 3 (HvMLH3) affects synapsis and crossover resolution in the barley desynaptic mutant des10Colas, I., Macaulay, M., Higgins, J. D., Phillips, D., Barakate, A., Posch, M., Armstrong, S. J., Franklin, F. C. H., Waugh, R. & Ramsay, L. 2016 In : New Phytologist.212, 3, p. 693-70714 p.
The effect of temperature on the male and female recombination landscape of barleyPhillips, D., Jenkins, G., Macaulay, M., Nibau, C., Wnetrzak, J., Fallding, D. S., Colas, I., Oakey, H., Waugh, R. & Ramsay, L. 2015 In : New Phytologist.208, 2, p. 421-429
Licensing MLH1 sites for crossover during meiosisMartin, A. C., Shaw, P., Phillips, D., Reader, S. & Moore, G. 2014 In : Nature Communications.5, 4580
CDKG1 protein kinase is essential for synapsis and male meiosis at high ambient temperature in Arabidopsis thalianaZheng, T., Nibau, C., Phillips, D. W., Jenkins, G., Armstrong, S. J. & Doonan, J. H. 2014 In : Proceedings of the National Academy of Sciences of the United States of America.111, 6, p. 2182-21876 p.
Quantitative high resolution mapping of HvMLH3 foci in barley pachytene nuclei reveals a strong distal bias and weak interferencePhillips, D. W., Wnetrzak, J., Nibau, C. S., Barakate, A., Ramsay, L., Wright, F., Higgins, J. D., Perry, R. M. & Jenkins, G. 2013 In : Journal of Experimental Botany.64, 8, p. 2139-215416 p.
High Resolution Analysis of Meiotic Chromosome Structure and Behaviour in Barley (Hordeum vulgare L.)Phillips, D. W., Nibau, C. S., Wnetrzak, J. & Jenkins, G. 2012 In : PLoS One.7, 6
Assaying pairing and recombination in barley (Hordeum vulgare)Phillips, D., Nibau, C., Wnetrzak, J., Ramsay, L. & Jenkins, G. 2011
Manipulation of meiotic recombination in barley (Hordeum vulgare)Wnetrzak, J., Phillips, D., Nibau, C., Fallding, D., Jones, N. & Jenkins, G. 2010 1 p.
Development of a molecular cytogenetic recombination assay for barleyPhillips, D., Nibau, C., Ramsey, L., Waugh, R. & Jenkins, G. 2010 In : Cytogenetic and Genome Research.129, 1-3, p. 154-1618 p.
Manipulating meiosis: Crossovers from Arabidopsis to cropsHalpin, C., Barakate, A., Waugh, R., Ramsay, L., Jenkins, G., Phillips, D., Armstrong, S., Higgins, J. & Franklin, C. 2009
Assaying recombination in barley (Hordeum vulgare)Phillips, D., Nibau, C., Fallding, D., Timofejeva, L., Jones, N. & Jenkins, G. 2009
Dissecting meiosis of rye using translational proteomicsPhillips, D. W., Mikhailova, E., Timofejeva, L., Mitchell, J. L., Osina, O., Sosnikhina, S. P., Jones, R. N. & Jenkins, G. 2008 In : Annals of Botany.101, 6, p. 873-8808 p.
Meiotic genes and proteins in cerealsJenkins, G., Phillips, D. W., Mikhailova, E., Timofejeva, L. & Jones, R. N. 2008 In : Cytogenetic and Genome Research.120, 3-4, p. 291-30111 p.
Molecular assembly of meiotic proteins Asy1 and Zyp1 and pairing promiscuity in rye (Secale cereale L.) and its synaptic mutant sy10Mikhailova, E. I., Phillips, D., Sosnikhina, S. P., Lovtsyus, A. V., Jones, R. N. & Jenkins, G. M. 2006 In : Genetics.174, 3, p. 1247-125812 p.
Models and meiosis in the ’omics eraJenkins, G., Mikhailova, E., Phillips, D., Hasterok, R., Draper, J. & Jones, R. N. 2005 Recent advances in genetics and breeding of the grasses. Zwierzykowski, Z. & Kosmala, A. (eds.). Polish Academy of Sciences, p. 97-1048 p.