Dr Russ Morphew

PhD

Module Coordinator

• AB1 Proteins and Enzymes (BR26620)
• AB1 Infection and Immunity (BRM1620)

Moderator

• AB1 Comparative Animal Physiology (BR16720)
• AB2 Parasitology (BR33820)

Lecturer

• AB2 Disease Diagnosis and Control (BR15420)
• AB1 Egwyddorion Gwyddoniaeth (blwyddyn 2) (VS20340)
• AB1 Gwyddor Filfeddygol (Blwyddyn 1) (VS11460)
• AB1 Invertebrate Zoology (BR25420)
• AB1 MBiol Research Project (BRM2860)
• AB2 Practical Skills for Biochemists (BR22920)
• AB1 Veterinary Infectious Diseases (BR34120)
• AB2 Veterinary Pharmacology and Disease Control (BR36820)
• AB1 Veterinary Science (Year 1) (VE11460)

Tutor

• AB2 Hot Topics in Parasite Control (BRM0920)
• AB1 Infection and Immunity (BRM1620)
• AB1 Integrated Year in Industry (BRS0060)
• AB1 MBiol Research Project (BRM2860)
• AB2 Parasitology (BR33820)
• AB1 Proteins and Enzymes (BR26620)
• AB1 Research Methods (BR27520)

Grader

• AB1 Research Project (BR36440)

Current research is aimed at utilising modern high resolution proteomic technologies and mass spectrometry to investigate protein function and interactions. This work has focussed upon microbial-host interactions and the proteins that act upon this interface. In particular, how proteins can facilitate the invasion, establishment or colonisation of an organism within a host. Present research focuses upon the interaction of of extracellular vesicles released from parasitic helminths on the microbiome. Of interest are the parasitic helminths of economic importance including the liver flukes Fasciola hepatica and F. gigantica, nematodes Haemonchus contortus and Teladorsagia circumcincta as well as neglected veterinary parasites such as the rumen fluke, Calicophoron daubneyi, and the equine tapeworm, Anoplocephala perfoliata. Recent research using high resolution proteomics has focussed upon vaccine discovery and the development and response to anthelmintic stress and metabolism. The main driver of future research is to increase our understanding of how proteins interact with other proteins within the same organism, between organisms or within a host. How proteins interact with ligands such as anthelmintics and metabolites are also of interest, including how proteins function in the metabolism and action of anthelmintics and ultimately anthelmintic resistance.