Dr Matthew Hegarty

PhD, PGCTHE

Dr Matthew Hegarty

Senior Lecturer

IBERS

Contact Details

Teaching

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Research

My research is focused on understanding how changes in the genome or transcriptome of an individual affects its phenotype, and also how genetic diversity affects populations. This research is based in a broad range of biological systems but always with a key theme of identifying genes underpinning physical traits. This is of particular relevance to the plant breeding and animal research programmes at IBERS, where my research brings a genomics aspect to these systems. I have a particular interest in the genetics of hybridisation and polyploidy, as many of the world's major crops are either polyploids or utilise hybrid vigour in their breeding.In addition to my own research interests, which heavily utilise the technology, I also oversee the IBERS Translational Genomics Facility, which supplies access to next-generation DNA sequencing and high-throughput genotyping for projects across IBERS and with collaborative partners.

Publications

Fu, Y, Thomas, A, Gasior, D, Harper, J, Gay, A, Jones, C, Hegarty, M, Asp, T, Fradera-Sola, A, Armstead, I & Fernandez-Fuentes, N 2021, 'A comparison of shared patterns of differential gene expression and gene ontologies in response to water-stress in roots and leaves of four diverse genotypes of Lolium and Festuca spp. temperate pasture grasses', PLoS One, vol. 16, no. 4, e0249636. https://doi.org/10.1371/journal.pone.0249636
The PollerGEN Consortium, Rowney, FM, Brennan, GL, Skjøth, CA, Griffith, GW, McInnes, RN, Clewlow, Y, Adams-Groom, B, Barber, A, de Vere, N, Economou, T, Hegarty, M, Hanlon, HM, Jones, L, Kurganskiy, A, Petch, GM, Potter, C, Rafiq, AM, Warner, A, Wheeler, B, Osborne, NJ & Creer, S 2021, 'Environmental DNA reveals links between abundance and composition of airborne grass pollen and respiratory health', Current Biology, vol. 31, no. 9, e4, pp. 1995-2003. https://doi.org/10.1016/j.cub.2021.02.019
Wititkornkul, B, Hulme, BJ, Tomes, JJ, Allen, NR, Davis, CN, Davey, SD, Cookson, AR, Phillips, HC, Hegarty, MJ, Swain, MT, Brophy, PM, Wonfor, RE & Morphew, RM 2021, 'Evidence of Immune Modulators in the Secretome of the Equine Tapeworm Anoplocephala perfoliata', Pathogens, vol. 10, no. 7, e912. https://doi.org/10.3390/pathogens10070912
Kurganskiy, A, Creer, S, De Vere, N, Griffith, GW, Osborne, NJ, Wheeler, BW, McInnes, RN, Clewlow, Y, Barber, A, Brennan, GL, Hanlon, HM, Hegarty, M, Potter, C, Rowney, F, Adams-Groom, B, Petch, GM, Pashley, CH, Satchwell, J, De Weger, LA, Rasmussen, K, Oliver, G, Sindt, C, Bruffaerts, N, The PollerGEN Consortium & Skjøth, CA 2021, 'Predicting the severity of the grass pollen season and the effect of climate change in Northwest Europe', Science Advances, vol. 7, no. 13, eabd7658. https://doi.org/10.1126/sciadv.abd7658
Blanco-Pastor, JL, Barre, P, Keep, T, Ledauphin, T, Escobar-Gutiérrez, A, Roschanski, AM, Willner, E, Dehmer, KJ, Hegarty, M, Muylle, H, Veeckman, E, Vandepoele, K, Ruttink, T, Roldán-Ruiz, I, Manel, S & Sampoux, JP 2020, 'Canonical correlations reveal adaptive loci and phenotypic responses to climate in perennial ryegrass', Molecular Ecology Resources. https://doi.org/10.1111/1755-0998.13289
More publications on the Research Portal