Dr Iain Chalmers


Dr Iain Chalmers

Senior Lecturer

Department of Life Sciences

Contact Details



Senior Lecturer in Veterinary Biosciences, Department of Life Sciences, Aberstwyth University, UK

Lecturer in Veterinary Biosciences, IBERS, Aberstwyth University, UK
EU-funded Post-Doctoral Research Associate, IBERS, Aberystwyth University, UK
Research Technician, IBERS, Aberystwyth University, UK
Wellcome Trust PhD programme, under supervision of Dr. Karl Hoffmann, Department of Pathology, University of Cambridge, UK
BSc (Hons.) Degree in Immunology, Edinburgh University, UK


My research focuses on the identification and characterisation of helminth proteins essential to the parasites survival in the host. The aim of this research is to discover novel vaccine candidates/drug targets and to also gain a deeper understanding of host/parasite interactions. Using bioinformatic approaches, my research also examines the evolution of gene families (such as the SmVAL family) across parasitic and non-parasitic species.


Degree Programme Coordinator BSc Veterinary Bisociences


Padalino, G, Celatka, C, Rienhoff Jr., HY, Kalin, JH, Cole, PA, Lassalle, D, Forde-Thomas, J, Chalmers, I, Brancale, A, Grunau, C & Hoffmann, K 2023, 'Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes', Wellcome Open Research, vol. 8, no. 146, 146. 10.12688/wellcomeopenres.18826.1
Oettle, RC, Dickinson, HA, Fitzsimmons, CM, Sacko, M, Tukahebwa, EM, Chalmers, IW, Wilson, S & Loke, P (ed.) 2023, 'Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like expression in Schistosoma haematobium and Schistosoma mansoni infection', PLOS Pathogens, vol. 19, no. 5, e1011037. 10.1371/journal.ppat.1011037, 10.17863/CAM.91264
White, R, Sotillo, J, Ancarola, ME, Borup, A, Boysen, AT, Brindley, PJ, Buzás, EI, Cavallero, S, Chaiyadet, S, Chalmers, IW, Cucher, MA, Dagenais, M, Davis, CN, Devaney, E, Duque-Correa, MA, Eichenberger, RM, Fontenla, S, Gasan, TA, Hokke, CH, Kosanovic, M, Kuipers, ME, Laha, T, Loukas, A, Maizels, RM, Marcilla, A, Mazanec, H, Morphew, RM, Neophytou, K, Nguyen, LT, Nolte-'t Hoen, E, Povelones, M, Robinson, MW, Rojas, A, Schabussova, I, Smits, HH, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, AH & Hoffmann, KF 2023, 'Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility', Journal of Extracellular Vesicles, vol. 12, no. 1, 12298. 10.1002/jev2.12298
Davey, SD, Chalmers, IW, Fernandez-Fuentes, N, Swain, MT, Smith, D, Abbas Abidi, SM, Saifullah, MK, Raman, M, Ravikumar, G, McVeigh, P, Maule, AG, Brophy, PM & Morphew, RM 2022, 'In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles', Molecular Omics, vol. 18, no. 1, pp. 45-56. 10.1039/D1MO00254F
Hulme, BJ, Geyer, KK, Forde-Thomas, JE, Padalino, G, Phillips, DW, Ittiprasert, W, Karinshak, SE, Mann, VH, Chalmers, IW, Brindley, PJ, Hokke, CH & Hoffmann, KF 2022, 'Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production', PLOS Pathogens, vol. 18, no. 1, e1009828. 10.1371/journal.ppat.1009828
More publications on the Research Portal