Dr Iain Chalmers

PhD

Dr Iain Chalmers

Lecturer in Veterinary Biosciences

Contact Details

Profile

2013-present
Lecturer in Veterinary Biosciences, IBERS, Aberstwyth University, UK
2010-2013
EU-funded Post-Doctoral Research Associate, IBERS, Aberystwyth University, UK
2008-2009
Research Technician, IBERS, Aberystwyth University, UK
2002-2009
Wellcome Trust PhD programme, under supervision of Dr. Karl Hoffmann, Department of Pathology, University of Cambridge, UK
1998-2002
BSc (Hons.) Degree in Immunology, Edinburgh University, UK

Teaching

Research

My research focuses on the identification and characterisation of helminth proteins essential to the parasites survival in the host. The aim of this research is to discover novel vaccine candidates/drug targets and to also gain a deeper understanding of host/parasite interactions. Using bioinformatic approaches, my research also examines the evolution of gene families (such as the SmVAL family) across parasitic and non-parasitic species.

Publications

Whole genome analysis of a schistosomiasis-transmitting freshwater snailAdema, C. M., Hillier, L. W., Jones, C. S., Loker, E. S., Knight, M., Minx, P., Oliveira, G., Raghavan, N., Shedlock, A., do Amaral, L. R., Arican-Goktas, H. D., Assis, J. G., Baba, E. H., Baron, O. L., Bayne, C. J., Bickham-Wright, U., Biggar, K. K., Blouin, M., Bonning, B. C., Botka, C., Bridger, J. M., Buckley, K. M., Buddenborg, S. K., Lima Caldeira, R., Carleton, J., Carvalho, O. S., Castillo, M. G., Chalmers, I. W., Christensens, M., Clifton, S., Cosseau, C., Coustau, C., Cripps, R. M., Cuesta-Astroz, Y., Cummins, S. F., Di Stephano, L., Dinguirard, N., Duval, D., Emrich, S., Feschotte, C., Feyereisen, R., Fitzgerald, P., Fronick, C., Fulton, L., Galinier, R., Gava, S. G., Geusz, M., Geyer, K. K., Giraldo-Calderón, G. I., de Souza Gomes, M., Gordy, M. A., Gourbal, B., Grunau, C., Hanington, P. C., Hoffmann, K. F., Hughes, D., Humphries, J., Jackson, D. J., Jannotti-Passos, L. K., De Jesus Jeremias, W., Jobling, S., Kamel, B., Kapusta, A., Kaur, S., Koene, J. M., Kohn, A. B., Lawson, D., Lawton, S. P., Liang, D., Limpanont, Y., Liu, S., Lockyer, A. E., Lovato, T. L., Ludolf, F., Magrini, V., Mcmanus, D. P., Medina, M., Misra, M., Mitta, G., Mkoji, G. M., Montague, M. J., Montelongo, C., Moroz, L. L., Munoz-Torres, M. C., Niazi, U., Noble, L. R., Oliveira, F. S., Pais, F. S., Papenfuss, A. T., Peace, R., Pena, J. J., Pila, E. A., Quelais, T., Raney, B. J., Rast, J. P., Rollinson, D., Rosse, I. C., Rotgans, B., Routledge, E. J., Ryan, K. M., Scholte, L. L. S., Storey, K. B., Swain, M., Tennessen, J. A., Tomlinson, C., Trujillo, D. L., Volpi, E. V., Walker, A. J., Wang, T., Wannaporn, I., Warren, W. C., Wu, X-J., Yoshino, T. P., Yusuf, M., Zhang, S-M., Zhao, M. & Wilson, R. K. 2017 In : Nature Communications.8, p. 15451 15451 (2017)
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoniGeyer, K., Niazi, U., Duval, D., Cosseau, C., Tomlinson, C., Chalmers, I., Swain, M., Cutress, D., Bickham-Wright, U., Munshi, S. E., Grunau, C., Yoshino, T. P. & Hoffmann, K. 2017 In : PLoS Neglected Tropical Diseases.11, 5, e0005246
Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel TreatmentChalmers, I. W., Fitzsimmons, C. M., Brown, M., Pierrot, C., Jones, F. M., Wawrzyniak, J. M., Fernandez-Fuentes, N., Tukahebwa, E. M., Dunne, D. W., Khalife, J. & Hoffmann, K. F. 2015 In : PLoS Neglected Tropical Diseases.9, 7, p. e0003920
Drug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7Reimers, N., Homann, A., Höschler, B., Langhans, K., Wilson, R. A., Pierrot, C., Khalife, J., Grevelding, C. G., Chalmers, I. W., Yazdanbakhsh, M., Hoffmann, K. F., Hokke, C. H., Haas, H. & Schramm, G. 2015 In : PLoS Neglected Tropical Diseases.9, 3, e0003593
Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human InfectionFarnell, E. J., Tyagi, N., Ryan, S., Chalmers, I. W., Pinot de Moira, A., Jones, F. M., Wawrzyniak, J., Fitzsimmons, C. M., Tukahebwa, E. M., Furnham, N., Maizels, R. M. & Dunne, D. W. 2015 In : Frontiers in Immunology.6, p. 26
More publications on the Research Portal