Prof Mike Young

Prof Mike Young

Emeritus Professor

IBERS

Contact Details

Research

Our laboratory studies post-exponential phase gene expression in several Gram-positive bacteria, including Bacillus and Clostridium. Recent work on dormancy in Micrococcus luteus led to the discovery of the Rpf family of bacterial growth factors found throughout the actinobacteria (e.g. mycobacteria, streptomycetes). We are currently exploring the mechanism of actions of these secreted bacterial growth factors and their potential applications for TB protection and therapy.

Publications

Aubrey, W, Riley, M, Young, M, King, RD, Oliver, SG & Clare, A 2015, 'A Tool for Multiple Targeted Genome Deletions that Is Precise, Scar-Free, and Suitable for Automation.' PLoS One, vol. 10, no. 12, 0142494. https://doi.org/10.1371/journal.pone.0142494
Guyot, S, Gervais, P, Young, M, Winckler, P, Dumont, J & Davey, H 2015, 'Surviving the heat: Heterogeneity of response in Saccharomyces cerevisiae provides insight into thermal damage to the membrane' Environmental Microbiology, vol. 17, no. 8, pp. 2982-2992. https://doi.org/10.1111/1462-2920.12866
Shleeva, M, Goncharenko, A, Kudykina, Y, Young, D, Young, M, Kaprelyants, A & Tailleux, L (ed.) 2013, 'Cyclic Amp-Dependent Resuscitation of Dormant Mycobacteria by Exogenous Free Fatty Acids' PLoS One, vol. 8, no. 12, e82914. https://doi.org/10.1371/journal.pone.0082914
Riley, MC, Aubrey, W, Young, M & Clare, A 2013, 'PD5: a general purpose library for primer design software' PLoS One, vol. 8, no. 11, e80156, pp. n/a. https://doi.org/10.1371/journal.pone.0080156
Bilsland, E, Sparkes, AC, Williams, KS, Moss, HJ, de Clare, M, Pir, P, Rowland, J, Aubrey, W, Pateman, R, Young, M, Carrington, M, King, RD & Oliver, SG 2013, 'Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds' Open Biology, vol. 3, no. 2, 120158. https://doi.org/10.1098/rsob.120158
More publications on the Research Portal