Dr Martin Swain

PhD

Dr Martin Swain

Senior Lecturer

Contact Details

Teaching

Module Coordinator
Lecturer

An introduction to Linux and Bioinformatics for PGM1520; Study and Communication Skills, BR12410; Molecular Laboratory Skills, BR12210; Research Methods, Dissertation, and a few lectures to other modules.

Research

I am interested in analysing large biological data sets from a variety of organisms, including plants, animals, parasites and microbes. Some recent and current projects include the sequencing of the tsetse fly and biomphalaria genomes, snake venom transcriptome analyses, methylation in flatworms, microRNAs, whole genome comparisons (of sheep and schistosomes), metagenomics of limpet guts and cryoconite, red clover transcriptomics, and the identification of neuropeptide receptors and functions in arthropods.

My other interests include the development of infrastructure and new software methodolgy for the handling and analysis of large data sets in bioinformatics. This involves high performance computing, technologies for data integration and data mining, and the development of new algorithms to analyse high-throughput sequencing data sets.

Publications

The importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogensDavis, C., Phillips, H., Tomes, J., Swain, M., Wilkinson, T., Brophy, P. & Morphew, R., 2019 , In : PLoS Neglected Tropical Diseases. e0007191.
Genome Sequencing and Comparative Transcriptomics Provide a Holistic View of 4-Nitrophenol Degradation and Concurrent Fatty Acid Catabolism by Rhodococcus sp. Strain BUPNP1Sengupta, K., Swain, M., Livingstone, P., Whitworth, D. & Saha, P., 2019 , In : Frontiers in Microbiology.9, 3209.
Homogeneous and heterogeneous populations of active rods in two-dimensional channelsKhodygo, V., Mughal, A. & Swain, M., 2019 , In : Physical Review E.
Polyomic tools for an emerging livestock parasite, the rumen fluke Calicophoron daubneyi; identifying shifts in rumen functionalityHuson, K. M., Morphew, R., Allen, N., Hegarty, M., Worgan, H., Girdwood, S., Jones, E. L., Phillips, H., Vickers, M., Swain, M., Smith, D., Kingston-Smith, A. & Brophy, P., 2018 , In : Parasites & Vectors.11, 1, 22 p., 617.
Transcriptomic analysis of crustacean neuropeptide signaling during the moult cycle in the green shore crab, Carcinus maenasOliphant, A., Alexander, J., Swain, M., Webster, S. G. & Wilcockson, D., 2018 , In : BMC Genomics.19, 711.
More publications on the Research Portal