Dr Amanda Lloyd

BSc: Genetics and biochemistry PhD: Metabolomics and plant pathology

Dr Amanda Lloyd

PDRA Clinical Trials & Scientific Co-ordinator- Future Foods


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Together with Prof John Draper and Dr Manfred Beckmann I am interested in developing standardised protocols for nutritional metabolomics investigations for monitoring metabolic changes in response to both acute and habitual dietary exposure. Techniques employed includes high throughput metabolomic fingerprinting based on Flow Infusion Electrospray Ionization-Mass Spectrometry (FIE-MS), accurate mass analysis using Fourier-Transform Ion Cyclotron Resonance Ultra MS (FT-ICR-MS) in conjunction with supervised multivariate data analysis (Principal Components Analysis, Linear Discriminant Analysis, Area Under the (Receiver operating characteristic) curve (AUC), and Random Forest) and ESI-MS signal annotation tools (MZedDB).


Beckmann, M, Wilson, T, Zubair, H, Lloyd, AJ, Lyons, L, Phillips, H, Tailliart, K, Gregory, N, Thatcher, R, Garcia-Perez, I, Frost, G, Mathers, JM & Draper, J 2020, 'A Standardized Strategy for Simultaneous Quantification of Urine Metabolites to Validate Development of a Biomarker Panel Allowing Comprehensive Assessment of Dietary Exposure', Molecular Nutrition and Food Research. https://doi.org/10.1002/mnfr.202000517
Lloyd, AJ, Willis, ND, Wilson, T, Zubair, H, Chambers, E, Garcia-Perez, I, Xie, L, Tailliart, K, Beckmann, M, Mathers, JC & Draper, J 2019, 'Addressing the pitfalls when designing intervention studies to discover and validate biomarkers or habitual dietary intake', Metabolomics, vol. 15, no. 5, 72. https://doi.org/10.1007/s11306-019-1532-3
Lloyd, A, Willis, ND, Wilson, T, Zubair, H, Xie, L, Chambers, ES, Garcia-Perez, I, Tailliart, K, Beckmann, M, Mathers, JC & Draper, J 2019, 'Developing a food exposure and urine sampling strategy for dietary exposure biomarker validation in free-living individuals', Molecular Nutrition and Food Research. https://doi.org/10.1002/mnfr.201900062
Wilson, T, Garcia-Perez, I, Posma, JM, Lloyd, A, Chambers, ES, Tailliart, K, Zubair, H, Beckmann, M, Mathers, JC, Holmes, E, Frost, G & Draper, J 2019, 'Spot and Cumulative Urine Samples Are Suitable Replacements for 24-Hour Urine Collections for Objective Measure of Dietary Exposure in Adults Using Metabolite Biomarkers', Journal of Nutrition. https://doi.org/10.1093/jn/nxz138
Lloyd, A, Beckmann, M, Wilson, T, Tailliart, K, Allaway, D & Draper, J 2017, 'Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry plasma lipidomics can distinguish between canine breeds despite uncontrolled environmental variability and non-standardized diets: Plasma lipidome of dog breeds using UHPLC-HRM', Metabolomics, vol. 13, 15. https://doi.org/10.1007/s11306-016-1152-0
More publications on the Research Portal