Dr Amanda Lloyd

BSc: Genetics and biochemistry PhD: Metabolomics and plant pathology

Dr Amanda Lloyd

PDRA Clinical Trials & Scientific Co-ordinator- Future Foods

IBERS

Contact Details

Research

Together with Prof John Draper and Dr Manfred Beckmann I am interested in developing standardised protocols for nutritional metabolomics investigations for monitoring metabolic changes in response to both acute and habitual dietary exposure. Techniques employed includes high throughput metabolomic fingerprinting based on Flow Infusion Electrospray Ionization-Mass Spectrometry (FIE-MS), accurate mass analysis using Fourier-Transform Ion Cyclotron Resonance Ultra MS (FT-ICR-MS) in conjunction with supervised multivariate data analysis (Principal Components Analysis, Linear Discriminant Analysis, Area Under the (Receiver operating characteristic) curve (AUC), and Random Forest) and ESI-MS signal annotation tools (MZedDB).

Publications

Beckmann, M, Wilson, T, Zubair, H, Lloyd, AJ, Lyons, L, Phillips, H, Tailliart, K, Gregory, N, Thatcher, R, Garcia-Perez, I, Frost, G, Mathers, JM & Draper, J 2020, 'A Standardized Strategy for Simultaneous Quantification of Urine Metabolites to Validate Development of a Biomarker Panel Allowing Comprehensive Assessment of Dietary Exposure', Molecular Nutrition and Food Research. https://doi.org/10.1002/mnfr.202000517
Beckmann, M, Lloyd, AJ, Wilson, T, Torres, DPM, Goios, ACL, Willis, ND, Lyons, L, Phillips, H, Mathers, JC, Nash, RJ, Sharp, H & Draper, J 2020, 'Calystegines are Potential Urine Biomarkers for Dietary Exposure to Potato Products', Molecular Nutrition and Food Research, vol. 64, 2000515. https://doi.org/10.1002/mnfr.202000515
Beckmann, M, Wilson, T, Lloyd, A, Torres, DPM, Goios, ACL, Willis, ND, Lyons, L, Phillips, H, Mathers, JM & Draper, J 2020, 'Challenges Associated With the Design and Deployment of Food Intake Urine Biomarker Technology for Assessment of Habitual Diet in Free-Living Individuals and Populations: A Perspective', Frontiers in Nutrition, vol. 7, 602515. https://doi.org/10.3389/fnut.2020.602515
Lloyd, A, Wilson, T, Willis, ND, Lyons, L, Phillips, H, Janssen, H, Stiegler, M, Xie, L, Tailliart, K, Beckmann, M, Stevenson, L, Mathers, JC & Draper, J 2020, 'Developing community-based urine sampling methods to deploy biomarker technology for assessment of dietary exposure', Public Health Nutrition, vol. 23, no. 17, pp. 3081–3092. https://doi.org/10.1017/S136898002000097X
Lloyd, AJ, Willis, ND, Wilson, T, Zubair, H, Chambers, E, Garcia-Perez, I, Xie, L, Tailliart, K, Beckmann, M, Mathers, JC & Draper, J 2019, 'Addressing the pitfalls when designing intervention studies to discover and validate biomarkers or habitual dietary intake', Metabolomics, vol. 15, no. 5, 72. https://doi.org/10.1007/s11306-019-1532-3
More publications on the Research Portal