Prof Luis Alejandro Jose Mur

PhD

Prof Luis Alejandro Jose Mur

Professor

Contact Details

Teaching

Research

In my Food Security Research I am interested in developing our understanding of the genetic & biochemical events associated with plant responses to stress & in identifying sources of tolerance/resistance. This work is based on the use of model plant species, Arabidopsis & Brachypodium distachyon & also crops, wheat (Triticum aestivum), oats (Avena sativa) tomato (Solanum esculentum) & barley (Hordeum vulgare).

My interests in clinical health focus on the respiratory tract & identifying drug leads from natural products. Lung cancer (LC) is the most prevalent cancer in the world with 1.3 million deaths recorded each year. Only 15% of patients live for five or more years after initial diagnosis, primarily due to late detection. Chronic obstructive pulmonary disease (COPD) is characterised by an increase in mucus production due to hyperplasia of goblet cells, & hypertrophy of mucus glands COPD is a leading cause of death, arising from acute exacerbations (sudden worsening of symptoms) which may be triggered by infection or environmental pollutants. My research in this area is focusing on the detection of metabolite biomarkers for LC & COPD & investigating possible links with the lung microbiome.

My research in bioactive natural products focus on identifying anti-microbial metabolites against such human pathogens as MSRA & Pseudomonas aeruginosa from invasive plant species & extremophile microbial strains.

I employ cutting edge genomic & post-genomic approaches but will use classical physiological, genetic, biochemical or microbiological approaches- as appropriate. I have numerous national & international collaborations which are supported by funding from the BBSRC, the EU, NSF (USA), DEFRA, Royal Society, Welsh Assembly, &

Publications

Gordon, SP, Contreras-Moreira, B, Woods, DP, Des Marais, DL, Burges, D, Shu, S, Stritt, C, Roulin, AC, Schackwitz, W, Tyler, L, Martin, J, Lipzen, A, Dochy, N, Phillips, J, Barry, K, Geuten, K, Budak, H, Jeunger, TE, Amasino, R, Caicedo, AL, Goodstein, D, Davidson, P, Mur, L, Figueroa, M, Freeling, M, Catalán, P & Vogel, JP 2017, 'Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure' Nature Communications, vol 8, 2184.
Nayyar, BG, Woodward, S, Mur, LAJ, Akram, A, Arshad, M, Saqlan Naqvi, SM & Akhund, S 2017, 'The Incidence of Alternaria Species Associated with Infected Sesamum indicum L. Seeds from Fields of the Punjab, Pakistan' Canadian Journal of Plant Pathology, vol 33, no. 6, pp. 543-553. DOI: 10.5423/PPJ.OA.04.2017.0081
Montilla-Bascón, G, Rubiales, D, Hebelstrup, KH, Mandon, J, Harren, FM, Cristescu, SM, Mur, LAJ & Prats, E 2017, 'Reduced nitric oxide levels during drought stress promote drought tolerance in barley and is associated with elevated polyamine biosynthesis' Scientific Reports, vol 7, no. 1, 13311. DOI: 10.1038/s41598-017-13458-1
Pierre, S, Griffith, G, Morphew, R, Mur, L & Scott, I 2017, 'Saprotrophic proteomes of biotypes of the witches’ broom pathogen Moniliophthora perniciosa' Fungal Biology, vol 121, no. 9, pp. 743-753. DOI: 10.1016/j.funbio.2017.05.004
Awan, SI, Ahmad, SD, Mur, L & Ahmed, MS 2017, 'Marker-Assisted Selection for Durable Rust Resistance in a Widely Adopted Wheat Cultivar "Inqilab-91"' International Journal of Agriculture and Biology. DOI: 10.17957/IJAB/15.0405
Zafari, S, Sharifi, M, Mur, L & Chashmi, NA 2017, 'Favouring NO over H2O2 production will increase Pb tolerance in Prosopis farcta via altered primary metabolism' Ecotoxicology and Environmental Safety, vol 142, pp. 293-302. DOI: 10.1016/j.ecoenv.2017.04.036
O'shea, K, Cameron, SJ, Lewis, KE, Lewis, PD, Lu, C & Mur, LA 2017, 'Corrigendum to Metabolomic-based biomarker discovery for non-invasive lung cancer screening: A case study [Biochimica et Biophysica Acta (BBA) – General subjects, vol. 1860 (2016), pp. 2682–2687]' Biochimica et Biophysica Acta (BBA) - General Subjects. DOI: 10.1016/j.bbagen.2017.02.015
Cameron, S, Lewis, KE, Huws, S, Hegarty, M, Lewis, PD, Pachebat, JA & Mur, L 2017, 'A pilot study using metagenomic sequencing of the sputum microbiome suggests potential bacterial biomarkers for lung cancer' PLoS One. DOI: 10.1371/journal.pone.0177062
Huang, Y, Ye, Y, Zhao, G, Wu, X, Kan, Y, Mur, L, Han, J & Qin, H 2017, 'An All-Solid-State Phosphate Electrode with H3PO4 Doped Polyaniline as the Sensitive Layer' International Journal of Electrochemical Science, vol 12, no. 6, pp. 4677-4691. DOI: 10.20964/2017.06.18
Novikova, GV, Mur, L, Nosov, AV, Fomenkov, AA, Mironov, KS, Mamaeva, AS, Shilov, ES, Rakitin, VY & Hall, M 2017, 'Nitric Oxide Has a Concentration-Dependent Effect on the Cell Cycle Acting via EIN2 in Arabidopsis thaliana Cultured Cells' Frontiers in Physiology, vol 8, 142. DOI: 10.3389/fphys.2017.00142
Mur, L, Simpson, C, Kumari, A, Gupta, AK & Gupta, KJ 2017, 'Moving nitrogen to the centre of plant defence against pathogens' Annals of Botany, pp. 703-709. DOI: 10.1093/aob/mcw179
Guo, Q, Meng, L, Humphreys, MW, Scullion, J & Mur, LAJ 2017, 'Expression of FlHMA3, a vacuolar P1B2-ATPase from Festulolium loliaceum, correlates with response to cadmium stress' Plant Physiology and Biochemistry, vol 112, pp. 270-277. DOI: 10.1016/j.plaphy.2017.01.013
Fisher, L, Han, J, Corke, F, Akinyemi, A, Didion, T, Nielsen, KK, Doonan, J, Mur, L & Bosch, M 2016, 'Linking dynamic phenotyping with metabolite analysis to study natural variation in drought responses of Brachypodium distachyon' Frontiers in Plant Science, vol 7, 1751. DOI: 10.3389/fpls.2016.01751
Sánchez-Martín, J, Montilla-Bascón, G, Mur, LAJ, Rubiales, D & Prats, E 2016, 'Compromised Photosynthetic Electron Flow and H2O2 Generation Correlate with Genotype-Specific Stomatal Dysfunctions during Resistance against Powdery Mildew in Oats' Frontiers in Plant Science, vol 7, 1660. DOI: 10.3389/fpls.2016.01660
Aiswarya, G, Mallika, V, Mur, L & Soniya, EV 2016, 'Ectopic expression and functional characterization of type III polyketide synthase mutants from Emblica officinalis Gaertn' Plant Cell Reports, vol 35, no. 10, pp. 2077-2090. DOI: 10.1007/s00299-016-2020-0
O'Shea, K, Cameron, SJS, Lewis, KE, Lewis, PD, Lu, C & Mur, LAJ 2016, 'Metabolomic-based biomarker discovery for non-invasive lung cancer screening: A case study' Biochimica et Biophysica Acta (BBA) - General Subjects, vol 1860, no. 11 (Part B), pp. 2682-2687. DOI: 10.1016/j.bbagen.2016.07.007
Gokul, J, Hodson, AJ, Saetnan, E, Irvine-Fynn, T, Westall, PJ, Detheridge, A, Takeuchi, N, Bussell, J, Mur, L & Edwards, A 2016, 'Taxon interactions control the distributions of cryoconite bacteria colonizing a High Arctic ice cap' Molecular Ecology, vol 25, no. 15, pp. 3752-3767. DOI: 10.1111/mec.13715
Cook, JM, Edwards, A, Bulling, M, Mur, LAJ, Cook, S, Gokul, JK, Cameron, KA, Sweet, M & Irvine-Fynn, TDL 2016, 'Metabolome-mediated biocryomorphic evolution promotes carbon fixation in Greenlandic cryoconite holes' Environmental Microbiology, vol 18, no. Thematic Issue, pp. 4674-4686. DOI: 10.1111/1462-2920.13349
Zampini, M, Mur, L, Rees Stevens, P, Pachebat, JA, Newbold, C, Hayes, F & Kingston-Smith, A 2016, 'Terminator Operon Reporter: Combining a transcription termination switch with reporter technology for improved gene synthesis and synthetic biology applications' Scientific Reports, vol 6, 26572. DOI: 10.1038/srep26572
Sivakumaran, A, Akinyemi, A, Mandon, J, Cristescu, SM, Hall, M, Harren, FJM & Mur, L 2016, 'ABA Suppresses Botrytis cinerea Elicited NO Production in Tomato to Influence H2O2 Generation and Increase Host Susceptibility' Frontiers in Plant Science, vol 7, 709. DOI: 10.3389/fpls.2016.00709
Catalán, P, Müller, J, Hasterok, R, Jenkins, G, Mur, LAJ, Langdon, T, Betekhtin, A, Siwinska, D, Pimentel, M & López-Alvarez, D 2012, 'Evolution and taxonomic split of the model grass Brachypodium distachyon' Annals of Botany, vol 109, no. 2, pp. 385-405. DOI: 10.1093/aob/mcr294
Allwood, JW, Heald, J, Lloyd, AJ, Goodacre, R & Mur, LAJ 2012, Separating the inseparable: The metabolomic analysis of plant-pathogen interactions. in NW Hardy & RD Hall (eds), Plant Metabolomics : Methods and Protocols. Methods in Molecular Biology.
Hebelstrup, KH, van Zanten, M, Mandon, J, Voesenek, LACJ, Harren, FJM, Cristescu, SM, Møller, IM & Mur, LAJ 2012, 'Haemoglobin modulates NO emission and hyponasty under hypoxia-related stress in Arabidopsis thaliana' Journal of Experimental Botany, vol 63, no. 15, pp. 5581-5591. DOI: 10.1093/jxb/ers210
Gupta, KJ, Hebelstrup, KH, Mur, LAJ & Igamberdiev, AU 2011, 'Plant hemoglobins: important playersat the crossroads between oxygen and nitric oxide' FEBS Letters, vol 585, no. 24, pp. 3843-3849. DOI: 10.1016/j.febslet.2011.10.036
Lewis, PD, Lewis, KE, Ghosal, R, Bayliss, S, Lloyd, AJ, Wills, J, Godfrey, R, Kloer, P & Mur, LAJ 2011, 'Evaluation of FTIR Spectroscopy as a diagnostic tool for lung cancer using sputum' BMC Cancer, vol 10, no. 640, 640. DOI: 10.1186/1471-2407-10-640
Brkljacic, J, Grotewold, E, Scholl, R, Mockler, TC, Garvin, DF, Vain, P, Brutnell, T, Sibout, R, Bevan, M, Budak, H, Caicedo, AL, Gao, C, Gu, Y-QQ, Hazen, SP, Holt III, BF, Hong, S-Y, Jordan, M, Manzaneda, AJ, Mitchell-Olds, T, Mochida, K, Mur, LAJ, Park, C-M, Sedbrook, J, Watt, M, Zheng, SJ & Vogel, JP 2011, 'Brachypodium as a model for the grasses: Today and the future' Plant Physiology, vol 157, no. 1, pp. 3-13. DOI: 10.1104/pp.111.179531
Lloyd, AJ, Allwood, JW, Winder, CL, Dunn, WB, Heald, JK, Cristescu, SM, Sivakumaran, A, Harren, FJM, Mulema, J, Denby, K, Goodacre, R, Smith, AR & Mur, LAJ 2011, 'Metabolomic approaches indicate that cell wall modifications play a major role in ethylene-mediated resistance against Botrytis cinerea' Plant Journal, vol 67, no. 5, pp. 852-868. DOI: 10.1111/j.1365-313X.2011.04639.x
Gupta, KJ, Bauve, H & Mur, LAJ 2011, 'Nitric oxide, nitrate reductase and UV-B tolerance' Tree Physiology, vol 31, no. 8, pp. 795-797. DOI: 10.1093/treephys/tpr080
Mur, LAJ, Allainguillaume, J, Catalán, P, Hasterok, R, Jenkins, G, Lesniewska, K, Thomas, I & Vogel, JP 2011, 'Exploiting the Brachypodium Tool Box in cereal and grass research' New Phytologist, vol 191, no. 2, pp. 334-347. DOI: 10.1111/j.1469-8137.2011.03748.x
Gay, AP, Mur, LAJ & Withers, CM 2011, 'Are stomatal responses the key to understanding the cost of fungal disease resistance in plants?' Journal of the Science of Food and Agriculture, vol 91, no. 9, pp. 1538-1540. DOI: 10.1002/jsfa.4423
van Doorn, WG, Beers, EP, Dangl, JL, Franklin-Tong, VE, Gallois, P, Hara-Nishimura, I, Jones, AM, Kawai-Yamada, M, Lam, E, Mundy, J, Mur, LAJ, Petersen, M, Smertenko, A, Taliansky, M, Van Breusegem, F, Wolpert, T, Woltering, E, Zhivotovsky, B & Bozhkov, PV 2011, 'Morphological classification of plant cell deaths' Cell Death and Differentiation, vol 18, no. 8, pp. 1241-1246. DOI: 10.1038/cdd.2011.36
Mur, LAJ, Mandon, J, Cristescu, SM, Harren, FJM & Prats, E 2011, 'Methods of nitric oxide detection in plants: A commentary' Plant Science, vol 181, no. 5, pp. 509-519. DOI: 10.1016/j.plantsci.2011.04.003
Bosch, M, Roberts, LA, Dalton, SJ, Robson, PR, Donnison, IS, Nielsen, K & Mur, LAJ 2011, 'Brachypodium as a model for studying traits relevant for the development of bioenergy grasses' 1st European Brachypodium Workshop, Versailles, France, 2011 - 2011, pp. Abstract No: P2.9.
Lewis, KE, Ghosal, R, Mur, LAJ, Bayliss, S, Kloer, P & Lewis, P 2011, 'Using Fourier Transform Infra-Red (FTIR) on sputum to develop a predictive model to differentiate lung cancer from healthy controls' American Journal of Respiratory and Critical Care Medicine, vol 183, pp. Paper A6098.
Hinch, DK, Gupta, KJ & Mur, LAJ 2010, 'NO way to treat a cold' New Phytologist, vol 189, no. 2, pp. 360-363. DOI: 10.1111/j.1469-8137.2010.03586.x
Mur, LAJ, Aubry, S, Mondhe, M, Kingston-smith, A, Gallagher, J, Timms-taravella, E, James, C, Papp, I, Hörtensteiner, S, Thomas, H & Ougham, H 2010, 'Accumulation of chlorophyll catabolites photosensitizes the hypersensitive response elicited by Pseudomonas syringae in Arabidopsis' New Phytologist, vol 188, no. 1, pp. 161-174. DOI: 10.1111/j.1469-8137.2010.03377.x
Allwood, JW, Clarke, A, Goodacre, R & Mur, LAJ 2010, 'Dual metabolomics: A novel approach to understanding plant-pathogen interactions' Phytochemistry, vol 71, no. 5-6, pp. 590-597. DOI: 10.1016/j.phytochem.2010.01.006
Prats, E, Gay, AP, Roberts, PC, Thomas, BJ, Sanderson, R, Paveley, N, Lyngkjaer, MF, Carver, TLW & Mur, LAJ 2010, 'Blumeria graminis interactions with barley conditioned by different single R genes demonstrate a temporal and spatial relationship between stomatal dysfunction and cell death' Phytopathology, vol 100, no. 1, pp. 21-32. DOI: 10.1094/PHYTO-100-1-0021
Ghosal, R, Lewis, KE, Kloer, P, Bayliss, S, Mur, LAJ & Lewis, PD 2010, Fourier transform infra-red (FTIR) spectroscopy on sputum from lung cancer patients, healthy controls and a high-risk cohort. in British Thoracic Society Winter Meeting 2010. pp. A19-A20, British Thoracic Society Winter Meeting 2010, London, United Kingdom of Great Britain and Northern Ireland, 2010. DOI: 10.1136/thx.2010.150912.38
Pierre, S, Mur, LAJ, Morphew, R, Hamilton, J, Scott, IM & Griffith, GW 2009, 'Proteomic analysis of the cacao pathogen Moniliophthora perniciosa' 16th International Cocoa Research Conference, Bali, Indonesia, 2009 - 2009, .
Mur, LAJ, Donnison, IS, Milbourne, D, Guiney, E, Byrne, S & Barth, S 2009, 'Identification of genes involved in the floral transition at the shoot apical meristem of Lolium perenne L. by use of suppression subtractive hybridisation' Plant Growth Regulation, vol 59, no. 3, pp. 215-225. DOI: 10.1007/s10725-009-9407-7
Kingston-Smith, A, Davies, T, Kyme, E & Mur, L 2009, 'The phytohormone salicylic acid influences autolysis in ruminantingested plant cells' Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, vol 153, no. 2 (Supplement), S160. DOI: 10.1016/j.cbpa.2009.04.323
Elwood, PC, Gallagher, AM, Duthie, GG, Mur, LAJ & Morgan, G 2009, 'Aspirin, salicylates and cancer' The Lancet, vol 373, no. 9671, pp. 1301-1309. DOI: 10.1016/S0140-6736(09)60243-9
Clarke, SM, Cristescu, SM, Miersch, O, Harren, FJM, Wasternack, C & Mur, LAJ 2009, 'Jasmonates interact with salicylic acid to confer basal thermotolerance in Arabidopsis thaliana' New Phytologist, vol 182, no. 1, pp. 175-187. DOI: 10.1111/j.1469-8137.2008.02735.x
Byrne, S, Guiney, E, Barth, S, Donnison, IS, Mur, LAJ & Milbourne, D 2009, 'Identification of coincident QTL for days to heading, spike length and spikelets per spike in Lolium perenne L.' Euphytica, vol 166, no. 1, pp. 61-70. DOI: 10.1007/s10681-008-9831-1
Sivakumaran, A, Mur, LAJ & Smith, AR 2009, 'Proteomic approaches to characterise the role of ethylene in tomato plants attached by Botrytis cinerea' Plant Sciences Wales, School of Biosciences, United Kingdom of Great Britain and Northern Ireland, 2009 - 2009, pp. p24.
Kloer, P, Ghosal, R, Mur, LAJ, Lewis, KE & Lewis, PD 2008, Fourier transform infrared spectroscopy and metabolic profiling in lung cancer. in Winter Meeting of the British-Thoracic-Society. pp. A60-A61, Winter Meeting of the British-Thoracic-Society, London, United Kingdom of Great Britain and Northern Ireland, 2008.
Mur, LAJ, Laarhoven, LJJ, Harren, FJM, Hall, M & Smith, AR 2008, 'Nitric oxide interacts with salicylate to regulate biphasic ethylene production during the hypersensitive response' Plant Physiology, vol 148, no. 3, pp. 1537-1546. DOI: 10.1104/pp.108.124404
Mur, LAJ, Lloyd, AJ, Cristescu, SM, Harren, FJM, Hall, M & Smith, A 2008, 'Biphasic ethylene production during the hypersensitive response in Arabidopsis: A window into defence priming mechanisms?' Plant Signaling and Behavior, vol 4, no. 7, pp. 610-613. DOI: 10.4161/psb.4.7.8904
Ougham, HJ, Hortensteiner, S, Armstead, IP, Donnison, IS, King, IP, Thomas, H & Mur, LAJ 2008, 'The control of chlorophyll catabolism and the status of yellowing as a biomarker of leaf senescence' Plant Biology, vol 10, no. S1, pp. 4-14. DOI: 10.1111/j.1438-8677.2008.00081.x
Gaupels, F, Furch, ACU, Will, T, Mur, LAJ, Kogel, K-H & Van Bel, AJE 2008, 'Nitric oxide generation in Vicia faba phloem cells reveals them to be sensitive detectors as well as possible systemic transducers of stress' New Phytologist, vol 178, no. 3, pp. 634-646. DOI: 10.1111/j.1469-8137.2008.02388.x
Prats, E, Carver, TLW & Mur, LAJ 2008, 'Pathogen-derived nitric oxide influences formation of the appressorium infection structure in the phytopathogenic fungus Blumeria graminis' Research in Microbiology, vol 159, no. 6, pp. 476-480. DOI: 10.1016/j.resmic.2008.04.001
Mur, LAJ 2008, 'Using Fourier transform infrared (FTIR) spectroscopy to evaluate metabolic markers in sputum in patients with and without lung cancer' 6th Annual BTOG Meeting 2008, Dublin, Iceland, 2008 - 2008, pp. S11-S11. DOI: 10.1016/S0169-5002(08)70033-3
Garvin, DF, Mur, LAJ, Hasterok, R, Jenkins, GM, Gu, Y-QQ, Hazen, SP, Mockler, TC & Vogel, JP 2008, 'Development of genetic and genomic research resources for Brachypodium distachyon, a new model system for grass crop research' Crop Science, vol 48, no. Supplement 1, pp. S69-S84. DOI: 10.2135/cropsci2007.06.0332tpg
Mur, LAJ, Kenton, P, Lloyd, AJ, Ougham, HJ & Prats, E 2007, 'The hypersensitive response; the centenary is upon us but how much do we know?' Journal of Experimental Botany, vol 59, no. 3, pp. 501-520. DOI: 10.1093/jxb/erm239
Prats, E, Carver, TLW, Gay, A & Mur, L 2007, 'Enemy at the Gates: Interaction-Specific Stomatal Responses to Pathogenic Challenge' Plant Signaling and Behavior, vol 2, no. 4, pp. 275-277. DOI: 10.4161/psb.2.4.4153
Johnson, HE, Smith, AR, Mur, LAJ, Causton, DR & Lloyd, AJ 2007, 'The application of MANOVA to analyse Arabidopsis thaliana metabolomic data from factorially designed experiments' Metabolomics, pp. 517-530. DOI: 10.1007/s11306-007-0065-3
Kingston-Smith, AH, Davies, T & Mur, LAJ 2007, 'Post-ingestion induction of plant cell death: Regulation and implications' pp. 200-. DOI: 10.1016/j.cbpa.2007.01.443
Harren, FJM, Mur, LAJ, Kenton, P, Smith, A & Laarhoven, L 2007, 'NO provides mainly avr-dependent inputs into cell death mechanisms associated with the hypersensitive response in tobacco' Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, vol 146, no. 4, pp. S256. DOI: 10.1016/j.cbpa.2007.01.644
Mur, L, Mondhe, M, Papp, I, Holton, N, Hoertensteiner, S, Kingston-Smith, A, Thomas, H & Ougham, H 2007, 'Throwing new light on the hypersensitive response' Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, vol 146, no. 4, C2.9. DOI: 10.1016/j.cbpa.2007.01.445
Lloyd, AJ, Smith, AR & Mur, LAJ 2007, Metabolomic approaches to understand ethylene mediated defenses in Arabidopsis thaliana against Botrytis cinerea. in A Ramina, C Chang, J Giovannoni, H Klee, P Perata & E Woltering (eds), Advances in Plant Ethylene Research., 77, Springer Nature, Dordrecht, pp. 359-368. DOI: 10.1007/978-1-4020-6014-4_77
Mur, LAJ, Carver, TLW & Prats, E 2006, 'NO way to live: the various roles of nitric oxide in plant-pathogen interactions' Journal of Experimental Botany, vol 57, no. 3, pp. 489-505. DOI: 10.1093/jxb/erj052
Prats, E, Gay, AP, Thomas, BJ, Mur, LAJ & Carver, TLW 2006, 'Stomatal lock-open, a consequence of epidermal cell death, follows transient suppression of stomatal opening in barley attacked by Blumeria graminis' Journal of Experimental Botany, pp. 2211-2226.
Mur, LAJ, Heald, JK, Allwood, JW, Goodacre, R & Ellis, DI 2006, 'Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory non-polar metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea.' Plant Journal, pp. 351-368. DOI: 10.1111/j.1365-313X.2006.02692.x
Atzorn, R, Mur, LAJ, Wasternack, C, Kenton, P & Miersch, O 2005, 'The outcomes of concentration-specific interactions between salicylate and jasmonate signaling include synergy, antagonism, and oxidative stress leading to cell death' Plant Physiology, vol 140, no. 1, pp. 249-262. DOI: 10.1104/pp.105.072348
Mur, LAJ, Clarke, A, Kenton, P & Darby, RM 2005, 'Harpin modulates the accumulation of salicylic acid by Arabidopsis cells via apoplastic alkalization' Journal of Experimental Botany, pp. 3129-3136. DOI: 10.1093/jxb/eri310
Harren, FJM, Smith, AR, Laarhoven, LJJ, Holton, NJ, Mur, LAJ & Santosa, IE 2005, 'Laser photoacoustic detection allows in planta detection of nitric oxide in tobacco following challenge with avirulent and virulent pseudomonas syringae pathovars' Plant Physiology, vol 138, no. 3, pp. 1247-1258. DOI: 10.1104/pp.104.055772
Draper, JH, Kenton, P & Mur, LAJ 2005, 'In planta measurements of oxidative bursts elicited by avirulent and virulent bacterial pathogens suggests that H2O2 is insufficient to elicit cell death in tobacco' Plant, Cell and Environment, pp. 548-561. DOI: 10.1111/j.1365-3040.2005.01301.x
Prats, E, Mur, LAJ, Sanderson, R & Carver, TLW 2005, 'Nitric oxide contributes both to papilla-based resistance and the hypersensitive response in barley attacked by Blumeria graminis f. sp.hordei' Molecular Plant Pathology, vol 6, no. 1, pp. 65-78. DOI: 10.1111/j.1364-3703.2004.00266.x
Guiney, E, Byrne, S, Donnison, IS, Mur, LAJ & Humphreys, MO (ed.) 2005, 'The investigation of flowering control in late/rare flowering Lolium perenne'.
Jenkins, G, Mur, L, Bablak, P, Hasterok, R & Draper, J 2004, Prospects for functional genomics in a new model grass. in D Leister (ed.), Plant Functional Genomics. Taylor & Francis.
Dalmadi, A, Koncz, C, Mur, LAJ, Papp, I & Dulai, S 2004, 'A mutation in the Cap Binding Protein 20 gene confers drought tolerance to Arabidopsis' Plant Molecular Biology, pp. 679-686. DOI: 10.1007/s11103-004-1680-2
Stoddart, WM, Xu, RL, Routledge, APM, Draper, JH, Casson, SA & Mur, LAJ 2004, 'Characterization of a proteinase inhibitor from Brachypodium distachyon suggests the conservation of defence signalling pathways between dicotyledonous plants and grasses' Molecular Plant Pathology, vol 5, no. 4, pp. 267-280. DOI: 10.1111/j.1364-3703.2004.00225.x
Scott, IM, Clarke, SM, Wood, JE & Mur, LAJ 2004, 'Salicylate accumulation inhibits growth at chilling temperature in Arabidopsis' Plant Physiology, vol 135, no. 2, pp. 1040-1049. DOI: 10.1104/pp.104.041293
Clarke, SM, Mur, LAJ, Wood, JE & Scott, IM 2004, 'Salicylic acid dependent signaling promotes basal thermotolerance but is not essential for acquired thermotolerance in Arabidopsis thaliana' Plant Journal, vol 38, no. 3, pp. 432-447. DOI: 10.1111/j.1365-313X.2004.02054.x
Routledge, APM, Draper, JH, Talbot, NJ, Smith, JV, Mur, LAJ & Shelley, G 2004, Magnaporthe grisea interactions with the model grass Brachypodium distachyon closely resemble those with rice (Oryza sativa). in Molecular Plant Pathology. Wiley, pp. 253-265. DOI: 10.1111/j.1364-3703.2004.00224.x
Farrell, GG, Sturgess, FJ, Mur, LAJ & Draper, JH 2004, 'The AoPR10 promoter and certain endogenous PR10 genes respond to oxidative signals in Arabidopsis' Molecular Plant Pathology, pp. 267-280.
Carver, TLW, Prats, E, Gay, A, Mur, L, Thomas, BJ & Kunoh, H 2004, 'Powdery mildew, cereal cells and sustainable crop production' Paper presented at 11th International Cereal Rust and Powdery Mildew Conference, Norwich, United Kingdom of Great Britain and Northern Ireland, 2004 - 2004, .
Hall, M, Moshkov, IE, Mur, LAJ, Novikova, GV & Smith, AR 2003, 'Ethylene regulates monomeric GTP-binding protein gene expression and activity in Arabidopsis' Plant Physiology, vol 131, no. 4, pp. 1705-1717. DOI: 10.1104/pp.014035
Moshkov, IE, Hall, M, Novikova, GV, Smith, AR & Mur, LAJ 2003, 'Ethylene rapidly up-regulates the activities of both monomeric GTP-binding proteins and protein kinase(s) in epicotyls of pea' Plant Physiology, pp. 1718-1726. DOI: 10.1104/pp.102.015057
Hall, M, Novikova, GV, Moshkov, IE, Mur, LAJ & Smith, AR 2002, 'Protein kinases in plants in the transduction of abiotic and biotic signals' Russian Journal of Plant Physiology (Fiziologiya rastenii), vol 49, no. 1, pp. 107-119. DOI: 10.1023/A:1013724614446
Bablak, P, Jenkins, GM, Ghosh-Biswas, GC, Routledge, APM, Mur, LAJ, Draper, JH & Hasterok, R 2001, 'Brachypodium distachyon. A new model system for functional genomics in grasses' Plant Physiology, pp. 1539-1555. DOI: 10.1104/pp.010196
Moshkov, IE, Smith, AR, Novikova, GV, Mur, LAJ & Hall, M 2001, 'Ethylene signal perception and transduction: multiple paradigms?' Biological Reviews, vol 76, no. 1, pp. 103-108. DOI: 10.1111/j.1469-185X.2000.tb00060.x
Mur, L, Brown, IR, Darby, R, Bestwick, CS, Bi, Y-M, Mansfield, JW & Draper, J 2000, 'A loss of resistance to avirulent bacterial pathogens in tobacco is associated with the attenuation of a salicylic acid-potentiated oxidative burst' Plant Journal, vol 23, no. 5, pp. 309-621. DOI: 10.1046/j.1365-313x.2000.00825.x
Cameron, S, Lewis, KE, Beckmann, M, Allison, G, Ghosal, R, Lewis, PD & Mur, L 2016, 'The metabolomic detection of lung cancer biomarkers in sputum' Lung Cancer, vol 94, pp. 88-95. DOI: 10.1016/j.lungcan.2016.02.006
Cameron, S, E. Lewis, K, Huws, S, Lin, W, Hegarty, M, D. Lewis, P, Mur, L & Pachebat, JA 2016, 'Metagenomic Sequencing of the Chronic Obstructive Pulmonary Disease Upper Bronchial Tract Microbiome Reveals Functional Changes Associated with Disease Severity' PLoS One, vol 11, no. 2, 0149095. DOI: 10.1371/journal.pone.0149095
James, L, Smith, J, Paveley, N, Mur, L & Brown, J 2016, Project Report No. 557: Screening for 'costs of disease resistance'. Agriculture and Horticulture Development Board.
Mandon, J, Mur, LAJ, Harren, FJM & Cristescu, SM 2016, Laser-Based Methods for Detection of Nitric Oxide in Plants. in KJ Gupta (ed.), Plant Nitric Oxide: Methods and Protocols. Methods in Molecular Biology, vol. 1242, Springer Nature, pp. 113-126. DOI: 10.1007/978-1-4939-3600-7_10
Zafari, S, Sharifi, M, Chashmi, NA & Mur, L 2015, 'Modulation of Pb-induced stress in Prosopis shoots through an interconnected network of signaling molecules, phenolic compounds and amino acids' Plant Physiology and Biochemistry, vol 99, pp. 11-20. DOI: 10.1016/j.plaphy.2015.12.004
Mur, L, Hauck, B, Winters, A, Heald, JK, Lloyd, AJ, Chakraborty, U & Chakraborty, BN 2015, 'The development of tea blister caused by Exobasidium vexans in tea (Camellia sinensis) correlates with the reduced accumulation of some antimicrobial metabolites and the defence signals salicylic and jasmonic acids' Plant Pathology, vol 64, no. 6, pp. 1471-1483. DOI: 10.1111/ppa.12364
Thomas, H, Ougham, H, Mur, L & Jansson, S 2015, Senescence and programmed cell death. in BB Buchanan, W Gruissem & RL Jones (eds), Biochemistry and Molecular Biology of Plants. Wiley, pp. 925-982.
Cameron, SJS, Huws, S, Hegarty, MJ, Smith, DPM & Mur, LAJ 2015, 'The human salivary microbiome exhibits temporal stability in bacterial diversity' FEMS Microbiology Ecology, vol 91, no. 9, fiv091. DOI: 10.1093/femsec/fiv091
Mamaeva, AS, Fomenkov, AA, Nosov, AV, Moshkov, IE, Mur, LAJ, Hall, MA & Novikova, GV 2015, 'Regulatory role of nitric oxide in plants' Russian Journal of Plant Physiology (Fiziologiya rastenii), vol 62, no. 4, pp. 427-440. DOI: 10.1134/S1021443715040135
Zampini, M, Rees Stevens, P, Pachebat, J, Kingston-Smith, A, Mur, L & Hayes, F 2015, 'RapGene: a fast and accurate strategy for synthetic gene assembly in Escherichia coli' Scientific Reports, vol 5, 11302. DOI: 10.1038/srep11302
Montilla-Bascón, G, Rispail, N, Sánchez-Martín, J, Rubiales, D, Mur, LAJ, Langdon, T, Howarth, CJ & Prats, E 2015, 'Genome-wide association study for crown rust (Puccinia coronata f. sp. avenae) and powdery mildew (Blumeria graminis f. sp. avenae) resistance in an oat (Avena sativa) collection of commercial varieties and landraces' Frontiers in Plant Science, vol 6, 103. DOI: 10.3389/fpls.2015.00103
Mur, L, Gupta, KJ, Chakraborty, U, Chakraborty, B & Hebelstrup, KH 2015, Ethylene, Nitric Oxide and Haemoglobins in Plant Tolerance to Flooding. in U Chakraborty & B Chakraborty (eds), Abiotic Stresses in Crop Plants. CABI Publishing, pp. 43-53.
Claes, J, Davies, T, Rees Stevens, P, Wilkinson, T, Mur, L & Kingston-Smith, A 2014, The effect of resistance to mildew infection on ruminal fermentation of Lolium perenne. in A Hopkins (ed.), EGF at 50: The future of European grasslands. Proceedings of the 25th General Meeting of the European Grassland Federation, Aberystwyth, Wales, 7-11 September 2014. : Grassland Science in Europe. vol. 19, Prifysgol Aberystwyth | Aberystwyth University, pp. 849, Proceedings of the 25th General Meeting of the European Grassland Federation, Aberystwyth, United Kingdom of Great Britain and Northern Ireland, 2014.
Edwards, A, Mur, L, Girdwood, S, Anesio, AM, Stibal, M, Edwards Rassner, S, Hell, K, Pachebat, J, Post, B, Bussell, JS, Cameron, S, Griffith, G, Hodson, AJ & Sattler, B 2014, 'Coupled cryoconite ecosystem structure–function relationships are revealed by comparing bacterial communities in alpine and Arctic glaciers' FEMS Microbiology Ecology, vol 89, no. 2, pp. 222-237. DOI: 10.1111/1574-6941.12283
Jones, AW, Cameron, SJS, Thatcher, R, Beecroft, MS, Mur, LAJ & Davison, G 2014, 'Effects of bovine colostrum supplementation on upper respiratory illness in active males' Brain, Behavior, and Immunity, vol 39, pp. 194-203. DOI: 10.1016/j.bbi.2013.10.032
Gupta, KJ, Mur, LAJ & Ratcliffe, RG 2014, 'Guarding the guard cells?' New Phytologist, vol 203, no. 2, pp. 349-351. DOI: 10.1111/nph.12882
Catalan, P, Chalhoub, B, Chochois, V, Garvin, DF, Hasterok, R, Manzaneda, AJ, Mur, LAJ, Pecchioni, N, Rasmussen, SK, Vogel, JP & Voxeur, A 2014, 'Update on the genomics and basic biology of Brachypodium: International Brachypodium Initiative (IBI)' Trends in Plant Science, vol 19, no. 7, pp. 414-418. DOI: 10.1016/j.tplants.2014.05.002
Ings, J, Mur, LAJ, Clifton-Brown, JC, Bosch, M & Robson, PR 2014, 'Revealing the Molecular and Physiological Responses to Water Deficit in the Bioenergy Crop Miscanthus x giganteus' Plant Biology Europe - FESPB/EPSO 2014 Congress, Dublin, Ireland, 2014 - 2014, pp. 34.
Gupta, KJ, Mur, LAJ & Brotman, Y 2014, 'Trichoderma asperelloides suppresses nitric oxide generation elicited by Fusarium oxysporum in Arabidopsis roots.' Molecular Plant-Microbe Interactions, vol 27, no. 4, pp. 307-314. DOI: 10.1094/MPMI-06-13-0160-R
Sanchez-Martin, J, Heald, J, Kingston-Smith, A, Winters, A, Rubiales, D, Sanz, M, Mur, L & Prats, E 2014, 'A metabolomic study in oats (Avena sativa) highlights a drought tolerance mechanism based on salicylate signalling pathways and the modulation of carbon, antioxidant and photo-oxidative metabolism' Plant, Cell and Environment. DOI: 10.1111/pce.12501
Montilla-Bascón, G, Sánchez-Martín, J, Rispail, N, Rubiales, D, Mur, L, Langdon, T, Griffiths, I, Howarth, C & Prats, E 2013, 'Genetic Diversity and Population Structure Among Oat Cultivars and Landraces' Plant Molecular Biology Reporter, vol 31, no. 6, pp. 1305-1314. DOI: 10.1007/s11105-013-0598-8
Mur, LAJ, Simpson, C, Gay, A, Paveley, N, Sanchez-Martin, J & Prats, E 2013, 'Stomatal lock-up following pathogenic challenge: Source or symptom of costs of resistance in crops?' Plant Pathology, vol 62, no. S1, pp. 72-82. DOI: 10.1111/ppa.12174
Kingston-Smith, AH, Davies, T, Rees Stevens, P & Mur, LAJ 2013, 'Comparative Metabolite Fingerprinting of the Rumen System during Colonisation of Three Forage Grass (Lolium perenne L.) Varieties' PLoS One, vol 8, no. 11, e82801. DOI: 10.1371/journal.pone.0082801
Ings, J, Mur, LAJ, Robson, PRH & Bosch, M 2013, 'Physiological and growth responses to water deficit in the bioenergy crop Miscanthus x giganteus' Frontiers in Plant Science, vol 4, pp. 468. DOI: 10.3389/fpls.2013.00468
Hebelstrup, KH, Shah, JK, Simpson, C, Schjoerring, JK, Mandon, J, Cristescu, SM, Harren, FJM, Christiansen, MW, Mur, LAJ & Igamberdiev, AU 2013, 'An assessment of the biotechnological use of hemoglobin modulation in cereals' Physiologia Plantarum. DOI: 10.1111/ppl.12115
Mur, LAJ, Hebelstrup, KH & Gupta, KJ 2013, 'Striking a balance:does nitrate uptake and metabolism regulate both NO generation and scavenging?' Frontiers in Plant Science, vol 4, 288. DOI: 10.3389/fpls.2013.00288
Allison, GG, Johnson, J, Poncon, C & Mur, LAJ 2013, 'Comparison of cell wall composition across 15 ecotypes of Brachypodium distachyon originating from the eastern and western Mediterranean' 1st International Brachypodium Conference, Modena, Italy, 2013 - 2013, .
Fisher, L, Mur, LAJ, Didion, T, Nielsen, KK & Bosch, M 2013, 'Exploiting Brachypodium to Identify Cell Wall-Specific Responses to Drought' 1st International Brachypodium Conference, Modena, Italy, 2013 - 2013, pp. S4.4.
Cristescu, SM, Marchenko, D, Mandon, J, Hebelstrup, KH, Griffith, GW, Mur, LAJ & Harren, FJM 2013, 'Spectroscopic monitoring of NO traces in plants and human breath: applications and perspectives' Applied Physics B: Lasers and Optics, vol 110, no. 2, pp. 203-211.
Mur, LAJ, Mandon, J, Persijn, S, Cristescu, SM, Moshkov, IE, Novikova, GV, Hall, M, Harren, FJM, Hebelstrup, KH & Gupta, KJ 2013, 'Nitric oxide in plants an assessment of the current state of knowledge' AoB PLANTS, vol 5, pls052. DOI: 10.1093/aobpla/pls052
Gupta, KJ, Brotman, Y, Segu, S, Zeier, T, Zeier, J, Persijn, ST, Cristescu, SM, Harren, FJM, Bauwe, H, Fernie, AR, Kaiser, WM & Mur, LAJ 2013, 'The form of nitrogen nutrition affects resistance against Pseudomonas syringae pv. phaseolicola in tobacco' Journal of Experimental Botany, vol 64, no. 2, pp. 553-568. DOI: 10.1093/jxb/ers348
Mur, LAJ, Prats, E, Pierre, S, Hall, M & Hebelstrup, KH 2013, 'Integrating nitric oxide into salicylic acid and jasmonic acid/ ethylene plant defense pathways' Frontiers in Plant Science, vol 4, 215. DOI: 10.3389/fpls.2013.00215
Jones, AW, Cameron, SJ, Thatcher, R, Beecroft, MS, Mur, L & Davison, G 2013, 'Exploring the mechanisms behind the effects of chronic bovine colostrum supplementation on risk of upper respiratory tract infection' 11th International Society of Exercise and Immunology symposium, Newcastle, Australia, 2013 - 2013, .
Sánchez-Martín, J, Mur, LAJ, Rubiales, D & Prats, E 2012, 'Targeting sources of drought tolerance within an Avena spp. collection through multivariate approaches' Planta, vol 236, no. 5, pp. 1529-1545. DOI: 10.1007/s00425-012-1709-8
Jones, RJ, Causton, DR, Emmett, B, Mur, LAJ & Gwynn-Jones, D 2012, 'Latent soil effects of grazing and ammonium deposition on Deschampsia flexuosa tillers inserted and grown in heather moorland soil' Environmental and Experimental Botany, vol 81, pp. 72-78. DOI: 10.1016/j.envexpbot.2012.02.006
Mur, LAJ, Sivakumaran, A, Mandon, J, Cristescu, SM, Harren, FJM & Hebelstrup, KH 2012, 'Haemoglobin modulates salicylate and jasmonate/ethylene-mediated resistance mechanisms against pathogens' Journal of Experimental Botany, vol 63, no. 12, pp. 4375-4387. DOI: 10.1093/jxb/ers116
Gupta, KJ, Kapuganti, J, Igamberdiev, AU & Mur, LAJ 2012, 'Commentary - NO and ROS homeostasis in mitochondria: a central role for alternative oxidase' New Phytologist, vol 195, no. 1, pp. 1-3. DOI: 10.1111/j.1469-8137.2012.04189.x
Manjunatha, G, Gupta, KJ, Lokesh, V, Mur, LAJ & Neelwarne, B 2012, 'Nitric oxide counters ethylene effects on ripening fruits' Plant Signaling and Behavior, vol 7, no. 4, pp. 476-483. DOI: 10.4161/psb.19523
Kingston-Smith, AH, Davies, TE, Edwards, JE, Gay, A & Mur, LAJ 2012, 'Evidence of a role for foliar salicylic acid in regulating the rate of post-ingestive protein breakdown in ruminants and contributing to landscape pollution' Journal of Experimental Botany, vol 63, no. 8, pp. 3243-3255. DOI: 10.1093/jxb/ers048
Salleh, FM, Evans, K, Goodall, B, Machin, H, Mowla, SB, Mur, LAJ, Runions, J, Theodoulou, FL, Foyer, CH & Rogers, HJ 2012, 'A novel function for a redox-related LEA protein (SAG21/AtLEA5) in root development and biotic stress responses' Plant, Cell and Environment, vol 35, no. 2, pp. 418-429. DOI: 10.1111/j.1365-3040.2011.02394.x