Dr David Whitworth


Dr David Whitworth



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My research focuses on the myxobacterial predator Myxococcus xanthus and how it preys upon other microbes. We are studying natural myxobacterial isolates using a variety of genomic, proteomic and phenotypic techniques to identify the genes conferring antimicrobial activity. Particular topics of interest include the predatory vesicles shed by myxobacteria, and myxobacterial signalling pathways and how they alter behaviour in response to a changing environment. In particular, I am interested in the social and predatory myxobacteria, and how they use two-component signalling pathways to co-ordinate group behaviour.


Whitworth, DE & Zwarycz, A 2020, 'A genomic survey of signalling in the myxococcaceae', Microorganisms, vol. 8, no. 11, 1739. https://doi.org/10.3390/microorganisms8111739
Whitworth, DE & Swain, MT 2020, 'A survey of non-coding RNAs in the social and predatory myxobacterium Myxococcus xanthus DK1622', Molecular Omics, vol. 16, no. 5, pp. 492-502. https://doi.org/10.1039/d0mo00068j
Chambers, J, Sparks, N, Sydney, N, Livingstone, P, Cookson, A & Whitworth, D 2020, 'Comparative Genomics and Pan-Genomics of the Myxococcaceae, including a Description of Five Novel Species: Myxococcus eversor sp. nov., Myxococcus llanfairpwllgwyngyllgogerychwyrndrobwllllantysiliogogogochensis sp. nov., Myxococcus vastator sp. nov., Pyxidicoccus caerfyrddinensis sp. nov., and Pyxidicoccus trucidator sp. nov.', Genome Biology and Evolution, vol. 12, no. 12, pp. 2289-230. https://doi.org/10.1093/gbe/evaa212
Whitworth, DE, Jurkevitch, E, Pérez, J, Fuhrmann, G & Koval, SF 2020, 'Editorial: Mechanisms of Prokaryotic Predation', Frontiers in Microbiology, vol. 11, 2071. https://doi.org/10.3389/fmicb.2020.02071
Livingstone, PG, Ingleby, O, Girdwood, S, Cookson, AR, Morphew, RM & Whitworth, DE 2020, 'Predatory Organisms with Untapped Biosynthetic Potential: Descriptions of Novel Corallococcus Species C. aberystwythensis sp. nov., C. carmarthensis sp. nov., C. exercitus sp. nov., C. interemptor sp. nov., C. llansteffanensis sp. nov., C. praedator sp. nov., C. sicarius sp. nov., and C. terminator sp. nov', Applied and Environmental Microbiology, vol. 86, no. 2, e01931-19. https://doi.org/10.1128/AEM.01931-19
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