Dr Hazel Davey PhD SFHEA

Dr Hazel Davey

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I am a Reader in Biology and Director of Taught Postgraduate Studies in the Institute of Biological, Environmental and Rural Sciences at Aberystwyth University. I am scheme coordinator for Microbiology and related degree schemes (C500, C501, C502, C509 and CC35) and for the postgraduate MRes Biosciences (C190). I am also an elected member of AU Senate and Council.Graduate of Aberystwyth University with a BSc in Zoology and Microbiology and a PhD on Flow Cytometry of Microorganisms.

Teaching

Research

Member of the Microbiology Research Group in IBERS.

Current focus

Microbial physiology using the model organism Saccharomyces cerevisiae in a biotechnologically relevant setting to understand viability and vitality, stress response and heterogeneity. Methods include flow cytometry, radio-frequency impedance spectroscopy, barcode arrays and multivariate data analysis methods. Part of this work is undertaken collaboratively with AU spin-out company Aber Instruments Ltd.

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Publications

2017

Davey, H. 2017. Tracking the fate of individual cells following exposure to heat stress. Environmental Microbiology 19 (2) pp. 411-412. 10.1111/1462-2920.13430 Cadair

2016

Klionsky, D., Abdelmohesen, K., Abe, A., Abedin, M.J., Abeliovich, H., Acebedo Arozena, A., Adachi, H., Adams, C.M., Adams, P.D., Adeli, K., Adhihetty, P.J., Adler, S.G., Agam, G., Davey, H., , 2016. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12 (1) pp. 1-222. 10.1080/15548627.2015.1100356 Cadair

2015

Guyot, S., Gervais, P., Young, M., Winckler, P., Dumont, J., Davey, H. 2015. Surviving the heat: Heterogeneity of response in Saccharomyces cerevisiae provides insight into thermal damage to the membrane. Environmental Microbiology 17 (8) pp. 2982-2992. 10.1111/1462-2920.12866 Other Cadair

2012

Evans, A.G.L., Davey, H.M., Cookson, A.R., Currinn, H., Cooke-Fox, G., Stanczyk, P.J., Whitworth, D.E. 2012. Predatory activity of Myxococcus xanthus outer-membrane vesicles and properties of their hydrolase cargo. Microbiology 158 (Pt 11) pp. 2742-2752. 10.1099/mic.0.060343-0 Cadair

Davey, H.M., Cross, E.J.M., Davey, C.L., Gkargkas, K., Delneri, D., Hoyle, D.C., Oliver, S.G., Kell, D.B., Griffith, G.W. 2012. Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability. Environmental Microbiology 14 (5) pp. 1249-1260. 10.1111/j.1462-2920.2012.02705.x Cadair

2011

Davey, H.M. 2011. Life, death and in-between: meanings and methods in microbiology. Applied and Environmental Microbiology 77 (16) pp. 5571-5576. 10.1128/AEM.00744-11 Cadair

Davey, H.M., Hexley, P. 2011. Red but not dead? Membranes of stressed Saccharomyces cerevisiae are permeable to propidium iodide. Environmental Microbiology 13 (1) pp. 163-171. 10.1111/j.1462-2920.2010.02317.x Cadair

Davey, H.M., Davey, C. 2011. Multivariate data analysis methods for the interpretation of microbial flow cytometric data. Advances in Biochemical Engineering/Biotechnology 124 pp. 183-209. 10.1007/10_2010_80 Cadair Other

2010

Davey, H.M. 2010. Prospects for the automation of analysis and interpretation of flow cytometric data. Cytometry Part A 77A (1) pp. 3-5. 10.1002/cyto.a.20835 Cadair

2009

Muller, S., Davey, H.M. 2009. Recent advances in the analysis of individual microbial cells. Cytometry Part A 75A pp. 83-85. 10.1002/cyto.a.20702 Cadair Other

2008

Delneri, D., Hoyle, D.C., Gkargkas, K., Cross, E.J.M., Rash, B., Zeef, L., Leong, H., Davey, H.M., Hayes, A., Kell, D.B., Griffith, G.W., Oliver, S.G. 2008. Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures. Nature Genetics 40 (1) pp. 113-117. 10.1038/ng.2007.49 Cadair Other

2007

Assunção, P., Antunes, N.T., Rosales, R.S., Poveda, C., de la Fe, C., Poveda, J.B., Davey, H.M. 2007. Application of flow cytometry for the determination of minimal inhibitory concentration of several antibacterial agents on Mycoplasma hyopneumoniae. Journal of Applied Microbiology 102 (4) pp. 1132-1137. 10.1111/j.1365-2672.2006.03170.x Cadair

2006

Assunção, P., Antunes, N.T., Rosales, R.S., de la Fe, C., Poveda, C., Poveda, J.B., Davey, H.M. 2006. Flow cytometric method for the assessment of the minimal inhibitory concentrations of antibacterial agents to Mycoplasma agalactiae. Cytometry Part A 69A (10) pp. 1071-1076. 10.1002/cyto.a.20331 Other Cadair

Assunção, P., Antunes, N.T., Rosales, R.S., Poveda, C., Poveda, J.B., Davey, H.M. 2006. Flow cytometric determination of the effects of antibacterial agents on Mycoplasma agalactiae, Mycoplasma putrefaciens, Mycoplasma capricolum subsp capricolum, and Mycoplasma mycoides subsp mycoides large colony type. Antimicrobial Agents and Chemotherapy 50 (8) pp. 2845-2849. 10.1128/AAC.01582-05 Other Cadair

2005

Kell, D.B., Brown, M., Davey, H.M., Dunn, W.B., Spasić, I., Oliver, S.G. 2005. Metabolic footprinting and systems biology: the medium is the message. Nature Reviews Microbiology 3 pp. 557-565. 10.1038/nrmicro1177 Cadair

2004

Allen, J., Davey, H.M., Broadhurst, D.I., Rowland, J.J., Oliver, S.G., Kell, D.B. 2004. Discrimination of the mode of action of antifungal substances using metabolic footprinting. Applied and Environmental Microbiology 70 (10) pp. 6157-6165. 10.1128/AEM.70.10.6157-6165.2004 Cadair

Kaderbhai, M.A., Davey, H.M., Kaderbhai, N.N. 2004. A directed evolution strategy for optimized export of recombinant proteins reveals critical determinants for preprotein discharge. Science 13 (9) pp. 2458-2469. 10.1110/ps.04697304 Other Cadair

2003

Allen, J., Davey, H.M., Broadhurst, D.I., Heald, J.K., Rowland, J.J., Oliver, S.G., Kell, D.B. 2003. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nature Biotechnology 21 pp. 692-696. 10.1038/nbt823 Other Cadair

Davey, H.M., Winson, M.K. 2003. Using flow cytometry to quantify microbial heterogeneity. Current Issues in Molecular Biology 5 pp. 9-15. Cadair Other

2002

Davey, H.M. 2002. Flow cytometric techniques for the detection of microorganisms. Methods in Cell Science 24 (1-3) pp. 91-97. 10.1023/A:1024106317540 Cadair

1996

Davey, H.M., Davey, C.L., Woodward, A.M., Edmonds, A.N., Lee, A.W., Kell, D.B. 1996. Oscillatory, Stochastic and Chaotic Growth Rate Fluctuations in Permittistatically-Controlled Yeast Cultures. BioSystems 39 (1) pp. 43-61. 10.1016/0303-2647(95)01577-9 Cadair

1993

Davey, C.L., Davey, H.M., Kell, D.B. 1993. Introduction to the dielectric estimation of cellular biomass in real time, with special emphasis on measurements at high volume fractions. Analytica Chimica Acta 279 (1) pp. 155-161. 10.1016/0003-2670(93)85078-X Other Cadair