Proteins and Enzymes

Cod y Modiwl: BR26620
Teitl y Modiwl: Proteins and Enzymes
Blwyddyn Academaidd: 2027/2028
Semester: Semester 1
Cyd-gysylltydd y Modiwl: Dr Russ Morphew
Rhestr Ddarllen: Gweld ar Aspire
Staff Eraill sy'n Cyfrannu: Dr Marco Arkesteijn; Dr Gordon Allison; Dr Ruth Wonfor; Dr Russ Morphew; Dr Ana Winters; Dr Ifat Shah; Professor David Whitworth

Dulliau Asesu

Math o Asesiad	Manylion Asesiad	Cyfran
Asesiad Semester	Data handling Worksheets: 20 Awr Covers Protein Sequencing, Enzyme Kinetics, Thermodynamics, REDOX and Protein Purification	50%
Asesiad Semester	Protein Portfolio: A synthesis of the module material culminating in a piece of written work submitted online. The use of experimental bioinformatics tools are also suggested. 2500 Words	50%
Asesiad Ailsefyll	Protein Portfolio: A synthesis of the module material culminating in a piece of written work submitted online. The use of experimental bioinformatics tools are also suggested. 2500 Words	50%
Asesiad Ailsefyll	Data Handling Worksheets: 20 Awr	50%

Canlyniadau Dysgu

Wedi cwblhau'r modiwl dylai'r myfyrwyr fedru:

Define how the amino acid sequence contributes to other levels of protein structure and the mechanism associated with protein folding.
Recount a variety of post-translational modifications of proteins and describe the processes which govern the targeting of proteins to specific organelles within the cell.
Explain how enzymes are assayed and how they can be isolated. Students should also be able to manipulate kinetic data to infer relevant parameters of enzymatic reactions.
Perform experimental protocols for the manipulation and characterisation of proteins and to report the results of such experimental investigations clearly and concisely.
Manipulate and utilise mathematical equations to enable the extraction of common protein biochemical parameters.

Disgrifiad cryno

The module is designed to extend and reinforce aspects of proteins dealt with in the first year. It will incorporate current research into proteins, folding of nascent proteins, post-translational modifications, working with proteins and manipulating protein biochemical data. The module aims to provide students with a firm understanding of the relationship between protein structure and protein function and how to apply this knowledge.

Cynnwys

The module is delivered through lectures, data handling sessions and two practical sessions.
The content will broadly cover:
Protein Structure; Enzymes and enzyme kinetics; Metal Co-factors and prosthetic groups, Protein folding; Protein Targeting; Experimenting and handling proteins; Protein biochemical data manipulation; Protein research.

Sgiliau Modiwl

Math o Sgiliau	Manylion Sgiliau
Cyfathrebu	Effective written communication skills will be developed to produce work for a wider audience through a protein portfolio database.
Datblygu personol a chynllunio gyrfa	This skill is not developed in this module .
Datrys Problemau	This skill is a key component of the module, working out how to find, interpret, and summarise information and present it in an accessible format.
Gwaith Tim	Students will work in pairs during the practical class.
Gwella dysgu a pherfformiad ei hun	Outside the formal contact hours, students will be expected to research materials, manage time and meet deadlines. The directed study elements will provide opportunity for students to explore their own learning styles and preferences and identify their needs and barriers to learning. Students will be able to review and monitor their progress and plan for improvement of personal performance.
Rhifedd	A significant component of the module is taught through data-handling problems .
Sgiliau pwnc penodol	Subject specific concepts relating to protein biochemistry and enzymology will be developed. Students will be able to demonstrate an understanding of integrated structure and function of proteins and evaluate pertinent protein properties. Students will also solve protein biochemical problems using numerical data and mathematical equations.
Sgiliau ymchwil	This is a research based module that requires students to assimilate knowledge from academic literature.
Technoleg Gwybodaeth	Accessing the web for information sources and using databases to find primary literature, preparation of coursework. Students will also be assessed through an online test.

Nodau

Mae'r modiwl hwn yn cydymffurfio a FfCChC Lefel 5